ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Impact of Low Dose Tacrolimus with Everolimus Regimen on Renal Pathology and T-Regulatory Cells in Kidney Transplant.

    A. Shetty,1 T. Opas,1 J. Mathew,1 V. Mas,2 J. Leventhal,1 N. Sustento-Reodica,1 L. Gallon.1

    1Northwestern University, Feinberg School of Medicine, Chicago, IL; 2University of Virginia, Charlottesville, VA.

    Calcineurin inhibitors (CNI) serve as the cornerstone of immunosuppression (IS) after kidney transplant. However chronic CNI nephrotoxicity has been implicated in allograft dysfunction. We hypothesize…
  • 2016 American Transplant Congress

    Prospective Randomized OPEN Trial Designed to Reduce the Incidence of Cytomegalovirus (CMV) Infection in DE NOVO Kidney Transplant Recipients Two-Year Results.

    R. Esmeraldo, M. Oliveira, P. Pinheiro, C. Girao, T. Freitas.

    Transplant, Hospital Geral de Fortaleza, Fortaleza, CE, Brazil.

    Introduction: CMV infection is a frequent complication following organ transplantation, and is associated with inferior long-term patient and graft survival. Here we report the results…
  • 2016 American Transplant Congress

    Better Long-Term Renal Function with Lower Incidence of Acute Rejection and Lower CMV Infection in Renal Transplant Patients Treated with a Combination of Tacrolimus and Everolimus.

    G. Spagnoletti, M. Salerno, V. Bianchi, N. Silvestrini, F. Apponi, J. Romagnoli, F. Citterio.

    Surgery - Renal Transplant Unit, Università Cattolica del Sacro Cuore, Rome, Italy.

    Introduction. Recent clinical trials have shown that the combination of CNIs with Everolimus (EVE) allows CNIs minimization, which may positively impact on chronic nephrotoxicity. Aim…
  • 2016 American Transplant Congress

    Factors and Outcomes Associated with Daptomycin Non-Susceptible Enterococcal Infections in Solid Organ Transplant Recipients.

    K. Younan,1 R. Lee,1 T. McCarty,1 D. Kunz,2 J. Locke,3 B. Camins,1 P. Pappas,1 J. Baddley,1 A. Nellore.1

    1Medicine, University of Alabama at Birmingham, Birmingham, AL; 2Pharmacy, University of Alabama at Birmingham, Birmingham, AL; 3Surgery, University of Alabama at Birmingham, Birmingham, AL.

    Background: Daptomycin non-susceptible enterococcal (DNSE) infections are associated with poor outcomes. Information regarding factors and outcomes of DNSE in solid organ transplant (SOT) recipients (SOTR)…
  • 2016 American Transplant Congress

    Prior Infection or Colonization with Carbapenem-Resistant Enterobacteriaceae Is Not an Absolute Contraindication for Solid Organ Transplantation.

    S. Huprikar,1 L. Casner,1 S. Pouch,2 M. Pinheiro Freire,3 R. Madan,4 E. Kwak,5 M. Satlin,6 P. Hartman,7 L. Pisney,8 P. Henrique Mourão,9 R. La Hoz,10 G. Patel.1

    1Mount Sinai, New York; 2Ohio State, Columbus; 3Sao Paulo University, Sao Paulo, Brazil; 4Albert Einstein, Bronx; 5University of Pittsburgh, Pittsburgh; 6Cornell, New York; 7Henry Ford Health System, Detroit; 8University of Colorado, Denver; 9Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; 10UT Southwestern, Dallas.

    BackgroundCarbapenem-resistant Enterobacteriaceae (CRE) infection is associated with poor outcomes after solid organ transplantation (SOT). The significance of CRE colonization or infection prior to SOT is…
  • 2016 American Transplant Congress

    Characteristics and Outcomes of Vancomycin Resistant Enterococcus Bacteremia After Liver Transplant.

    R. Odrobina,1 C. Kovacs,1 R. Butler,2 C. Koval.1

    1Department of Infectious Diseases, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    Vancomycin Resistant Enterococcus (VRE) infection is reported in 5-20% of liver transplant (LT) recipients and is associated with decreased survival. Published data includes infections of…
  • 2016 American Transplant Congress

    Colonization and Risk of Bacteremia by Multi-Drug Resistant Organisms in Intestinal Transplant Recipients.

    J. Simkins,1 J. Camargo,1 M. Morris,1 R. Vianna,2 T. Beduschi,2 L. Abbo.1

    1Medicine/Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL; 2Surgery, Miami Transplant Institute/University of Miami, Miami, FL.

    Background: This study is the first to evaluate colonization rates and subsequent bacteremia with multi-drug resistant organisms (MDRO) in intestinal transplant (ITx) recipients.Methods: Retrospective study…
  • 2016 American Transplant Congress

    The Impact of Pre-Transplant Infections on Post-Liver Transplant Outcomes.

    S. Ngo, J. Levitsky, M. Ison.

    Divisions of Infectious Diseases, Hematology and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL.

    Background: Pre- and Post-liver transplant infections are a common cause of morbidity and mortality in orthotopic liver transplant (OLT) patients. How pre-transplant infections affect early…
  • 2016 American Transplant Congress

    Clinical Impact of the Verigene® Blood Culture System on Rapid Diagnosis and Antibiotic Optimization in Bacteremic Solid Organ Transplant (SOT) Recipients.

    N. Law,1 G. Malat,3,4 D. Lee,1 A. Doyle,2 C. Emery,1,5 K. Kyle,5 K. Ranganna,2 M. Harhay,2 T. Bias.1,4

    1Division of Infectious Diseases and HIV Medicine, Drexel University College of Medicine, Philadelphia, PA; 2Division of Nephrology, Drexel University College of Medicine, Philadelphia, PA; 3Department of Surgery, Drexel University College of Medicine, Philadelphia, PA; 4Pharmacy, Hahnemann University Hospital, Philadelphia, PA; 5Microbiology, Hahnemann University Hospital, Philadelphia, PA.

    Background:Bloodstream infections are a major concern in SOT recipients and ineffective antibiotic therapy is strongly associated with poor outcomes. Rapid diagnostic tests (RDT) provide prompt…
  • 2016 American Transplant Congress

    Pediatric Access to Kidney Transplantation Under KAS.

    W. Cherikh,1 D. Stewart,1 A. Kucheryavaya,1 M. Aeder,2 E. Brewer.3

    1UNOS, Richmond, VA; 2Univ. Hosp. Case Med Ctr, Cleveland, OH; 3Texas Children's Hosp/Baylor College Medicine, Houston, TX.

    Background. Under the kidney allocation system (KAS) implemented on Dec 4, 2014, pediatric (ped) priority is now based on Kidney Donor Profile Index (KDPI) <35%…
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