Abstracts Archive - Page 132 of 1683 - ATC Abstracts

2022 American Transplant Congress
Survival Comparison of Simultaneous Pancreas-Kidney Transplant with Pancreas After Living-Donor Kidney Transplant by Wait Time and Organ Quality
G. R. Lyden¹, E. S. Helgeson², E. B. Finger³, A. J. Matas³, J. J. Snyder⁴, D. M. Vock²
¹Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute; Division of Biostatistics, University of Minnesota, Mpls, MN, ²Div Biostatistics U MN, Mpls, MN, ³Dept Surg U MN, Mpls, MN, ⁴Hennepin Healthcare Research Institute, Mpls, MN
*Purpose: The survival benefit of simultaneous pancreas-kidney (SPK) compared to pancreas after living-donor kidney (PALK) transplant is controversial. Wait times for SPK and donor risk…
2022 American Transplant Congress
The Impact Of Covid-19 On Pediatric Organ Donation And Transplantation
E. Lee¹, X. Zhang², G. Mazariegos³, T. Nakagawa⁴
¹Transplant Surgery, UPMC Childrens Hospital of Pittsburgh, Pittsburgh, PA, ²UPMC Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ³Children's Hospital of Pittsburgh, Pittsburgh, PA, ⁴Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Florida College of Medicine, Jacksonville, FL
*Purpose: The global COVID-19 pandemic has significantly altered delivery of healthcare. Hospital resource utilization has been impacted on multiple levels including solid organ transplantation and…
2022 American Transplant Congress
Desensitization Protocol Consisting of High-Dose Intravenous Immunoglobulin, Plasmapheresis, and Rituximab in Highly Sensitized Kidney Transplant Recipients
M. Okada, T. Hiramitsu, T. Tomosugi, K. Futamura, S. Narumi, N. Goto, Y. Watarai
Nagoya Daini Red Cross Hospital, Nagoya, Japan
*Purpose: In HLA incompatible kidney transplantation, donor-specific HLA antibody often causes antibody-mediated rejection (AMR). To prevent AMR, we adopted a preoperative desensitization protocol including high-dose…
2022 American Transplant Congress
Deletion of Fibroblastic Reticular Cell Derived Laminin A4 Impairs Lymph Node Vasculature and Conduits
L. Li¹, M. Shirkey¹, W. Piao¹, A. Kensiski¹, V. Saxena¹, T. Zhang¹, X. Li², J. Zhao², S. Gavzy¹, R. Abdi², J. Bromberg¹
¹UMB, Baltimore, MD, ²Harvard University, Boston, MA
*Purpose: Fibroblastic reticular cells (FRCs) support lymph node (LN) structure by producing various functional extracellular matrix (ECM) components. We hypothesized that FRCs and their ECM…
2022 American Transplant Congress
Impaired Humoral Response to Second Dose of BNT162b2 Messenger RNA COVID-19 Vaccine in Kidney Transplant Recipients in Japan: Prospective Observational Study
H. Sasaki¹, K. Hasegawa¹, M. Miura², H. Harada¹, D. Takamoto¹, Y. Takada¹, S. Harada¹, H. Tanaka¹
¹Sapporo City General Hospital, Sapporo, Japan, ²Sapporo Hokuyu Hospital, Sapporo, Japan
*Purpose: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has a major impact on solid organ transplant (SOT) recipients, with mortality rate up to 22%. The…
2022 American Transplant Congress
Identification of a Human B Cell State with Allogeneic Antigen Cross-Presenting Potential
U. Bhatia, E. C. Guinan
Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA
*Purpose: B cells are known to play a significant role in allograft tolerance or rejection, largely determined by production of cytokines and antibodies that suppress…
2022 American Transplant Congress
An Updated Estimate of Post-Transplant Survival After Implementation of the New Donor Heart Allocation Policy
K. A. Lazenby¹, N. Narang², K. M. Pelzer³, G. Ran¹, W. F. Parker³
¹Pritzker School of Medicine, University of Chicago, Chicago, IL, ²Advocate Heart Institute, Advocate Christ Medical Center, Chicago, IL, ³Department of Medicine, University of Chicago, Chicago, IL
*Purpose: Published estimates showing lower post-transplant survival after implementation of the new heart allocation policy may be biased downward due to incomplete follow-up on surviving…
2022 American Transplant Congress
Impact of Glecaprevir/Pibrentasvir on Tacrolimus Concentration in Solid Organ Transplant Recipients with or without Triazole Antifungal Therapy
D. Abraham¹, A. Feist², N. Law¹, S. Aslam¹, V. Nguyen¹
¹University of California San Diego Health, San Diego, CA, ²University of California San Diego, San Diego, CA
*Purpose: Provide guidance on tacrolimus (TAC) dose adjustments during glecaprevir/pibrentasvir (GLE/PIB) initiation and discontinuation in patients on triazole antifungals by comparing changes in TAC concentration-dose…
2022 American Transplant Congress
Sars-cov-2 Antibodies Transitions After Vaccination In Solid Organ Transplant Recipients: Multicenter Study In Japan
K. Unagami¹, M. Yoshikawa², Y. Natori³, K. Omoto¹, H. Ishida¹, H. Date⁴, R. Imamura⁵, T. Ito⁴, K. Miyaji⁶, S. Takahara⁷, K. Yuzawa⁸, O. Satoko⁹, Y. Hirota¹⁰, H. Egawa¹
¹Tokyo Women's Medical University, Tokyo, Japan, ²Kyoto Prefectural University of Medicine, Kyoto, Japan, ³University of Miami, Pinecrest, FL, ⁴Kyoto University, Kyoto, Japan, ⁵Dept. of Urology, Osaka Univ. Graduate School of Medicine, Suita, Japan, ⁶Renal Transplantation, Takatsuki General Hospital, Takatsuki, Japan, ⁷Kansai Medical Hospital, Toyonaka, Japan, ⁸Tranplantation Surgery, National Hospital Organization Mito Medical Center, Mito, Japan, ⁹Public Health, Osaka City University Graduate School of Medicine and Research Center for Infectious, Osaka City University Graduate School of Medicine, Osaka, Japan, ¹⁰Clinical Epidemiology Research Center, Miyama, Japan
*Purpose: For purpose of SARS-CoV-2 infection control, vaccination was started in worldwide, however, low reactivity of antibody production after vaccination is a concern for solid…
2022 American Transplant Congress
Incidence of De Novo Donor Specific Antibodies After Early Steroid Withdrawal in Kidney Transplant Recipients
D. Majmundar, S. Karhadkar, A. Diamond, J. Au, C. Ruggia-Check
Temple University Hospital, Philadelphia, PA
*Purpose: Early steroid withdrawal (ESW) regimens may lead to the formation of de novo donor-specific antibodies (dnDSA) post-kidney transplant, which increases the risk of antibody-mediated…