ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    A Multicenter Randomized Controlled Trial To Compare The Efficacy Of Ex-vivo Machine Perfusion With Static Cold Storage In Human Liver Transplantation: The University Of Maryland Experience

    J. Avruch1, N. Goussous2, S. Malik1, M. Pinedo1, R. Meier1, C. Bhati1, D. Maluf1, R. Barth3, J. Alvarez-Casas1

    1Transplant Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Transplant Surgery, University of California Davis Health, Davis, CA, 3University of Chicago, Chicago, IL

    *Purpose: There is accumulating clinical evidence of the benefit of normothermic ex-vivo machine perfusion (NMP) compared with traditional static cold storage of liver allografts prior…
  • 2022 American Transplant Congress

    A Single-Center Cross-Sectional Analysis of Lipid Management in Kidney Transplant Recipients: Is It Time to Reassess KDIGO Guidelines?

    R. Saranu1, J. Pandav1, M. Balusu2, J. Azzi1, M. Y. Yeung1, M. McGrath1, E. Abdel-Basset1, S. Gabardi1, A. Chandraker1

    1Renal Division, Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA

    *Purpose: Cardiovascular disease remains the leading cause of mortality after kidney transplant, accounting for more than 30% of total deaths. Dyslipidemia is common following transplantation,…
  • 2022 American Transplant Congress

    Waitlisted and Transplant Patient Perspectives on Expanding Access to Deceased Donor Kidney Transplants

    C. Rosaasen1, N. Rosaasen2, R. Mainra3, A. Trachtenberg4, J. Ho5, C. Parsons6, S. Delaney6, H. Mansell7

    1Johnson Shoyama School of Public Policy, University of Saskatchewan, Saskatoon, SK, Canada, 2Saskatchewan Transplant Program, Saskatchewan Health Authority, Saskatoon, SK, Canada, 3Division of Nephrology, Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada, 4, Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada, 5Department of Internal Medicine and Department of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada, 6Canadian Blood Services, Edmonton, AB, Canada, 7University of Saskatchewan, Saskatoon, SK, Canada

    *Purpose: A concerning number of kidneys (expanded donor criteria, extended criteria, or marginal kidneys) are discarded yearly, and novel solutions are needed to solve the…
  • 2022 American Transplant Congress

    Evolution of the Need for Transplant Evaluations for Liver Failure Decompensation After TIPS

    N. Kemmer1, V. Sureshkumar2, L. Grater3, G. Hoots4, S. Agrawal1, K. Robichaux5, M. Gosselin3, S. Mohammed5, A. Kumar6, J. Buggs7

    1Transplant Hepatology, Tampa General Hospital, Tampa, FL, 2Lake Erie College of Osteopathic Medicine, Bradenton, FL, 3University of Tampa, Tampa, FL, 4Radiology, Tampa General Hospital, Tampa, FL, 5University of South Florida, Tampa, FL, 6Morsani College of Medicine, University of South Florida, Tampa, FL, 7Transplant Surgery, Tampa General Hospital, Tampa, FL

    *Purpose: Portal hypertension is described as an increased pressure gradient between the portal and systemic circulation which can result in severe complications. Transjugular Intrahepatic Portosystemic…
  • 2022 American Transplant Congress

    Liver and Kidney Transplantation from Donation After Circulatory Death Heart Donors in the US: Better Early Outcomes with Normothermic Regional Perfusion versus Cold Flush

    M. Rosenzweig1, R. Ruiz2, E. Martinez1, A. Gupta1, H. Fernandez1, S. Lee1, N. Onaca1, J. Bayer1, G. J. McKenna1, T. Ma1, G. Testa3, A. Wall1

    1Baylor University Medical Center, Dallas, TX, 2Baylor University Medical Center, Fort Worth, TX, 3Baylor Dallas, Dallas, TX

    *Purpose: Donation after circulatory death (DCD) heart donation is increasingly common in the US. The two methods for DCD heart donation are normothermic regional perfusion…
  • 2022 American Transplant Congress

    Additional Dose of SARS-CoV-2 Vaccine Increases Neutralization Capacity in Solid Organ Transplant Recipients

    Y. Yoo1, J. Husson2, T. Iraguha3, S. Niederhaus4, X. Wen5, A. Crane5, A. Carrier5, J. Avruch5, A. Ahuja6, M. Mathew7, S. Dahiya8, A. P. Rapoport8, D. Atanackovic8, K. K. Saharia2

    1Inst of Human Virology, Baltimore, MD, 2Div of Infect Diseases, Univ of Maryland School of Med. and Inst of Human Virology, Baltimore, MD, 3Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD, 4Dept of Surgery, Univ of Maryland School of Med., Baltimore, MD, 5Dept of Surgery, Univ of Maryland Med. Center, Baltimore, MD, 6Dept of Medicine, Univ of Maryland Med. Center, Baltimore, MD, 7Div of Infect. Diseases, Univ of Maryland Med. Center, Baltimore, MD, 8Dept of Medicine, Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD

    *Purpose: Solid organ transplant recipients (SOTR) develop weak antibody responses after SARS-CoV-2 vaccination. Published data on neutralizing activity of plasma, a better measure of protection,…
  • 2022 American Transplant Congress

    Single Nuclei RNA-Sequencing Identifies Distinct Immune Cell Profile in Kidney Allograft Fibrosis

    J. McDaniels1, A. Shetty1, C. Kuscu2, C. Kuscu2, T. Rousselle1, E. Bardhi1, C. Drachenberg1, M. Talwar2, J. Eason2, T. Muthukumar3, D. Maluf1, V. Mas1

    1University of Maryland Baltimore, Baltimore, MD, 2UTHSC, Memphis, TN, 3Weill Cornell Medicine, New York, NY

    *Purpose: A major obstacle after kidney transplantation (KT) is chronic allograft dysfunction characterized by interstitial fibrosis and tubular atrophy (IFTA). Despite extensive research, the cellular…
  • 2022 American Transplant Congress

    Time-Dependent Blood Eosinophilia Count Increases the Risk of Kidney Allograft Rejection

    L. Colas1, L. Bui2, C. Kerleau3, M. Lemdani4, K. Autain-Renaudin5, A. Magnan6, M. Giral3, S. Brouard1

    1CRT2I, Université de Nantes, Nantes, France, 2Service de Néphrologie, Centre Hospitalier de Mouscron, Mouscron, Belgium, 3Service de Néphrologie et Immunologie Clinique, CHU de Nantes, Nantes, France, 4Département de Biomathématiques, Université de Lilles, Lilles, France, 5Service d'Anatomie et Cytologie Pathologique, CHU de Nantes, Nantes, France, 6INRAe UMR 0892, Université de Versailles Saint-Quentin Paris-Saclay, Paris, France

    *Purpose: There is growing evidence that type 2 immune effectors (immunoglobulin E, eosinophils, mast cells/basophils) play a role in autoimmune disorders and solid organ transplantation.…
  • 2022 American Transplant Congress

    Characterization of Acute Kidney Injury in Fatty Liver Ischemia Reperfusion Injury

    Z. P. Rokop, W. Zhang, N. Ghosh, A. Das, N. Biswas, C. Sen, C. Kubal

    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: The association between hepatic ischemia reperfusion injury (hIRI) and acute kidney injury (AKI) has been well established. AKI is commonly observed following transplantation of…
  • 2022 American Transplant Congress

    What If Only Days After Dialysis Counted Towards Kidney Candidates’ Qualified Waiting Times?

    G. R. Vece, K. Lindblad, M. Stuart, B. Carrico, D. Stewart, D. Klassen, S. Diallo

    Research, United Network for Organ Sharing, Richmond, VA

    *Purpose: Current kidney policy allows patients who have not yet initiated dialysis to qualify for allocation priority based on the time since a recorded eGFR…
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