2016 American Transplant Congress
Outcomes of Isolated Pediatric Small Intestine Transplants Using Vascular Homografts.
MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC.
Background/aim: Pediatric intestinal transplantation has changed recently with more isolated small intestine transplants being performed in small children instead of combined liver-intestine transplants. Consequently, surgical…2016 American Transplant Congress
Generation of Naïve Donor-Derived Lymphocytes from Graft-Resident Lymphoid Progenitors After Human Intestinal Transplantation.
Columbia University, New York.
Multivisceral transplantation (MVTx) is associated with a lower rate of severe graft rejection than isolated intestinal transplantation (iITx). We recently demonstrated that mixed T cell…2016 American Transplant Congress
Increased Waitlist Death and Removal in Pediatric Liver Transplant Recipients Denied Exception Requests.
Purpose: Over 30% of children listed for liver transplant (LT) have exceptions filed to increase their PELD/MELD. Non-standard exception requests (NSER) are granted by regional…2016 American Transplant Congress
Long-Term Outcomes After Pediatric Liver Transplantation for Malignant Liver Tumors: Effects of Era and Age.
Background: Hepatoblastoma (HB), hepatocellular carcinoma (HCC), along with hemangioendothelioma, hemangiosarcoma, and angiosarcoma (HHA) are rare tumors in children that are treated with orthotopic liver transplantation…2016 American Transplant Congress
Sudden Increase in Allocation Score for Pediatric Liver Transplant Candidates Predicts Waitlist Mortality.
Allocation for deceased donor livers is prioritized in the U.S. by waitlist mortality, as predicted by PELD for children<12 years, and MELD for individuals>12 years.…2016 American Transplant Congress
Long Term Outcome of De-Novo Autoimmune Hepatitis in Pediatric Recipients of Liver Transplantation.
Background: De-novo autoimmune hepatitis (DAIH) is a chronic immune mediated graft disorder seen following liver transplantation (LT). The long-term course and outcome of DAIH is…2016 American Transplant Congress
The Medication Level Variability Index (MLVI), a Behavioral Biomarker, Predicts Late Allograft Rejection in Pediatric Liver Transplant Recipients – A Prospective Multisite Study.
Objective: The MALT [Medication Adherence in children who had a Liver Transplant (LT), NCT-01154075, R01DK080740 (NIDDK)] multisite study prospectively evaluated a biomarker for erratic medication…2016 American Transplant Congress
Utility of a Routine Bench Cholangiogram for Deceased Split Liver Procedure.
Background: Biliary complications can result in a significant morbidity for split liver graft recipients. The segmental biliary anatomy, particularly the left biliary system is poorly…2016 American Transplant Congress
Identification of MicroRNAs in EBV+ B Cell Lymphomas and Secreted Exosomes.
Division of Abdominal Transplantation, Dept. of Surgery, Stanford University, Stanford.
Introduction Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of organ transplantation commonly associated with Epstein Barr virus (EBV) infection. EBV viral loads are…2016 American Transplant Congress
Examining the Risk for Post-Transplant Viral Infections and Lymphoproliferative Disorder (PTLD) in Kidney Transplant Patients (Pts) Receiving Calcineurin Inhibitor-Based Immunosuppression (CNI-IS) Compared to Belatacept (CTLA4Ig).
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Introduction: CTLA4Ig is a novel IS agent that acts through costimulatory blockade of T-cells and obviates the need for CNI. Despite benefits in improving renal…