2016 American Transplant Congress
Development of a Vascularized Thymus-Sternum Composite Tissue Allograft Model in Non-Human Primates.
Surgery, University of Maryland, Baltimore, MD.
Purpose: Vascularized composite allotransplantation (VCA) has demonstrated clinical success with standard immunosuppressive strategies in face, hand, and forearm transplantations. We developed a non-human primate model…2016 American Transplant Congress
Vascularized Composite Allograft Tolerance with Transient High-Dose Tacrolimus Across a Full MHC Mismatch in a Large Animal Model.
Department of Plastic Surgery, Johns Hopkins University, Baltimore, MD.
PURPOSE: Vascularized composite allografts (VCA) can enhance the quality of life of patients with severe facial or extremity injuries, and the induction of tolerance would…2016 American Transplant Congress
Systematic Pathological Component Scores for Skin-Containing Vascularized Composite Allografts.
Successful application of skin-containing vascularized composite allografts (VCA) depends on accurate assessment of the graft status typically based on skin biopsies. A working classification (Banff…2016 American Transplant Congress
Latest VCA Statistics in the U.S.
Background. On July 3, 2014, the Organ Procurement and Transplantation Network/United Network for Organ Sharing (OPTN/UNOS) was charged with the oversight of Vascularized Composite Allograft…2016 American Transplant Congress
Ex Situ Perfusion of a Human Limb for 24 Hours.
Background: Vascularized composite tissue (limb) allografts are procured and cold stored (4[deg]C) until surgery. This process is time limited as the tissue has to be…2016 American Transplant Congress
Intestinal Retransplantation in Children: Single Center Experience.
Aim: To analyze the patient and graft characteristics and improvement in patient outcomes for intestinal retransplantation (Re-ITx) in the era of induction immunosuppression with the…2016 American Transplant Congress
Normothermic Ex-Vivo Perfusion of the Intestine: The Introduction of an Innovative Physiologic Model with Novel Biomarkers.
General Surgery, Transplant Center, Cleveland Clinic Foundation, Cleveland, OH.
Purpose: Ischemia reperfusion injury is a major risk factor for short and long-term functional survival after intestinal transplantation. Normothermic machine perfusion is an emerging biotechnology…2016 American Transplant Congress
IL-17-Producing CCR6+CD4+ Th17 Cells Drive Intestinal Allograft Rejection in Humans.
MedStar Georgetown Transplant Institute, Washington DC.
A. Allograft rejection remains a significant source of mortality and morbidity in intestinal transplant (ITx) recipients. However, the underlying mechanisms remain unclear. The purpose of…2016 American Transplant Congress
Conditional Long Term Intestine Patient and Graft Survival Is Improving Under rATG Immunosuppression in Pediatric Intestine Transplantation.
Aim: We reviewed conditional graft survival and short and long term improvements in children receiving rATG (rabbit anti-thymocyte globulin) immunosuppression for intestine transplantation at a…2016 American Transplant Congress
Innate Lymphoid Cells Play a Key Role in Controlling Antimicrobial Defense in Intestinal Transplant Recipients.
MedStar Georgetown Transplant Institute, Washington DC.
A. Infectious complications are the leading cause of death early after intestinal transplantation (ITx). Etiologies underlying this remain unclear. Innate lymphoid cells (ILCs) have very…
American Transplant Congress abstracts