ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Pediatric Split Liver Transplantation: Single Center Experience.

    A. Elsabbagh,1,2 C. Williams,1 R. Girlanda,1 C. Desai,1 J. Hawksworth,1 A. Kroemer,1 C. Matsumoto,1 T. Fishbein.1

    1MedStar Georgetown Transplant Institute, Georgetown University Hospital, Washington, DC; 2Gastroenterology Surgical Center, Mansoura University, Mansoura, Egypt.

    Background: Split liver transplantation allows for expansion of the pool of organs for pediatric liver transplantation.Objectives: To assess overall outcomes in pediatric split liver transplantation…
  • 2016 American Transplant Congress

    Combined Liver-Kidney Transplantation in Children: Long-Term Follow-Up in 27 Children.

    M. Kemper,1 B. Nashan,2 L. Fischer,2 F. Brinkert.1

    1Pediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Hepatobiliary and Transplantation Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

    Combined liver and kidney transplantation (CLKT) is an important treatment option for patients suffering from diseases like autosomal recessive polycystic kidney disease (ARPKD) or primary…
  • 2016 American Transplant Congress

    Biopsy-Proven Rejection in Children After Liver Transplantation Is Associated by an IL-12p40-Mediated Innate Immune Response Followed by Th1 T Cell Activation.

    C. Falk,1 I. Goldschmidt,2 F. Mutschler,2 E. Pfister,2 F. Lehner,3 J. Keil,1 C. Neudörfl,1 A. Karch,4 R. Mikolajczyk,4 U. Baumann.2

    1Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Bitte Wählen, Germany; 2Department of Pediatric Hepatology, Hannover Medical School, Hannover, Bitte Wählen, Germany; 3Department of Abdominal and Transplantation Surgery, Hannover Medical School, Hannover, Bitte Wählen, Germany; 4Department of Epidemiology, Helmholtz Center for Infection Research, HZI, Braunschweig, Germany.

    Sustained by adaptive immune cells and their soluble mediators is well established for infection but it has not been demonstrated for solid organ transplantation in…
  • 2016 American Transplant Congress

    Incidence and Factors Associated with De Novo DSA After BK Viremia in Renal Transplant Recipients.

    S. Patel, S. Kuten, R. Knight, D. Nguyen, E. Graviss, A. Gaber.

    Houston Methodist Hospital, Houston, TX.

    Recent literature indicates an elevated rate of de novo DSA (dnDSA) following BK viremia (BKV) in renal transplant recipients (RTR). We sought to review our…
  • 2016 American Transplant Congress

    Identification of Donor HLA-Specific Antibodies as a Risk Factor for Graft Dysfunction and Failure Following BK Virus Associated Nephropathy.

    E. Abuhelaiqa, S. Salvatore, J. Lee, J. Lee, V. Sharma, T. Muthukumar, S. Seshan, M. Suthanthiran, D. Dadhania.

    Transplantation Medicine, Weill Cornell Medicine, New York, NY.

    Background: BK virus associated nephropathy (BKVN) has emerged as a significant cause of graft dysfunction and graft failure. Identification of risk factors for graft dysfunction…
  • 2016 American Transplant Congress

    Slipping Through the Cracks: Late Onset BK Viremia.

    J. Gandhi,1 M. Mackenzie,1 D. DeWolfe,2 F. Cardarelli,3 M. Pavlakis,3 C. Tan.1,4

    1Center for Virology & Vaccine Research, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA; 2Division of Nephrology, BIDMC, Boston, MA; 3The Transplant Institute, BIDMC, Boston, MA; 4Division of Infectious Disease, BIDMC, Boston, MA.

    Introduction: Most studies indicate that viremia caused by BK virus (BKV), the step preceding BKV associated nephropathy (BKVN) in kidney transplant recipients (KTRs), occurs within…
  • 2016 American Transplant Congress

    Neutrophil-to-Lymphocyte Ratio as a Predictor of Polyomavirus BK Nephropathy in Kidney Transplant Patients.

    K. Masutani,1 A. Tsuchimoto,1 Y. Matsukuma,1 K. Kaku,2 K. Kurihara,2 Y. Okabe,2 K. Tsuruya,1 M. Nakamura,2 T. Kitazono.1

    1Department of Medicine and Clinical Science, Kyushu University, Fukuoka, Japan; 2Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan.

    Background: Neutrophil-to-lymphocyte ratio (NLR) is an index for systemic inflammatory response, and has been reported to be a prognostic marker in the patients with malignancies…
  • 2016 American Transplant Congress

    Impact of BKV Subtype Distribution on BKV Nephropathy, Viremia, and Renal Outcome in Patients After Renal Transplantation.

    S. Anke,1 L. Silvia,1 H. Hermann,1 H. Albert,2 S. Corinna.2

    1Nephrology, Hannover Medical School, Hannover, Germany; 2Virology, Hannover Medical School, Hannover, Germany.

    Factors determining the course of BK viral (BKV) infection remain uncertain. We studied the role of BKV subtype distribution in BKV-infected patients after renal transplantation.-We…
  • 2016 American Transplant Congress

    Increased Gene Expression of TGF-β in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Polyomavirus BK Viremi.

    W. Yin,1 M. Lu.2

    1Surgery, School of Medicine, Tzu Chi University, Hualien, Taiwan, Division of General Surgery, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia-I, Dalin, Taiwan; 2Allergy, Immunology and Rheumatology, School of Medicine, Tzu Chi University, Hualien, Taiwan, Division of Allergy, Immunology and Rheumatology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia-I, Dalin, Taiwan.

    We aimed to investigate the roles of cytokines during polyomavirus BK (BKV) reactivation in renal transplant patients. Forty-eight renal allograft recipients were enrolled in this…
  • 2016 American Transplant Congress

    Simultaneous Pancreas/Kidney Transplantation Increases the Risk of Late-Onset BKV-Associated Nephropathy.

    T. Schachtner,1,2 M. Zaks,1 A. Kahl,1 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany.

    Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with BKV-associated nephropathy (BKVN) being the most important infectious cause of allograft loss. Comparisons of BKVN…
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