ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Effect of Donor-Recipient Gender Mismatch in Liver Transplant Recipients: A Post-Hoc Analysis of the H2304 Study.

    L. Fischer, P. de Simone, G. Dong, P. Lopez, P. Bernhardt, F. Saliba.

    H2304 study group, Hamburg, Germany.

    Purpose: Donor-recipient gender mismatch may play a role in liver transplant (LTx) outcomes. Here we present the 24-month results from the post-hoc analysis of the…
  • 2016 American Transplant Congress

    Evaluating the Influence of Liver Donor and Recipient Race on Tacrolimus Dose Requirements.

    J. Knorr, J. Vidal, V. Navarro, R. Zaki.

    Einstein Medical Center, Philadelphia, PA.

    Background: The majority of liver transplant recipients (LTR) receive tacrolimus (TAC) to prevent allograft rejection. Early establishment of therapeutic levels is imperative to efficacy. Several…
  • 2016 American Transplant Congress

    Pre-Transplant Risk Factors: Predicting Nonadherence and Rejection in Adult Liver Transplant Recipients.

    S. Lieber,1 J. Helcer,1 E. Leven,1 C. Knight,2 C. Wlodarkiewicz,2 A. Shenoy,1 E. Shemesh,1 S. Florman,3 T. Schiano,3 R. Annunziato.1

    1Icahn School of Medicine Mount Sinai Hospital, NY; 2Fordham University, NY; 3Recanati/Miller Transplant Institute Mount Sinai Hospital, NY.

    Purpose: The pre-liver transplant (LT) psychosocial evaluation aims to identify risk factors for immunosuppression nonadherence (NA) and poor post-LT outcomes. Despite broad support for these…
  • 2016 American Transplant Congress

    Adding an Antimetabolite to a Calcineurin-Inhibitor-Based Immunosuppression Regimen Leads to Improved Native Renal Function After Liver Transplantation.

    A. Karim, D. Conway, G. Leverson, J. Mezrich, L. Fernandez, A. D'Alessandro, D. Foley.

    Surgery, University of Wisconsin, Madison, WI.

    Background: Nephrotoxic side effects of calcineurin inhibitors (CNI) have been well established. The addition of anti-metabolites (AM) to CNI-based immunosuppression (IS) regimens has been proposed…
  • 2016 American Transplant Congress

    Preoperative Cytokine Storm in High MELD Patients Accentuates Incidence of Rejection Following Liver Transplantation.

    A. Mathur, E. Presbyskowski, E. Zorn, K. Rogers, J. Guarrera, B. Samstein, A. Griesemer, K. Halazun, T. Kato, J. Emond.

    Abdominal Transplant Surgery, Columbia University, NY, NY.

    IntroductionAcute Cellular Rejection (ACR) affects 30 percent of all liver transplants. Histologically it is characterized by cellular inflammation in the veins, bile ducts and portal…
  • 2016 American Transplant Congress

    Early Tacrolimus Exposure in Patients Treated De Novo with Once-Daily Tacrolimus After Liver Transplantation: Relationship with Acute Rejection and Long-Term Outcome.

    M. Gastaca, A. Valdivieso, J. Bustamante, P. Ruiz, J. Fernandez, A. Ventoso, M. Testillano, I. Palomares, M. Prieto, P. Salvador, A. Matarranz, M. Suarez, J. Ortiz de Urbina.

    Liver Transplantation Unit, Cruces University Hospital, Bilbao, Vizcaya, Spain.

    AIM: The aim of our study was to define the possible influence of early tacrolimus exposure on long-term outcomes in patients treated with de novo…
  • 2016 American Transplant Congress

    Sublingual Tacrolimus in Liver Transplantation: A Valid Option?

    M. Moreno Gonzales,1 L. Myhre,2 T. Taner.1

    1Division of Transplantation Surgery, Mayo Clinic, Rochester, MN; 2Department of Pharmacy, Mayo Clinic, Rochester, MN.

    Introduction. Oral tacrolimus (Tac) is currently the pilar of maintenance immunosuppression following solid organ transplantation and the most common route of drug delivery. Recent studies…
  • 2016 American Transplant Congress

    Deceased Non-A2 Donor ABO-Incompatible Liver Transplantation – Promising Results with Anti-A/B Antibody Reduction Both Pre- and Post-Transplant.

    U. Dahlgren,1 G. Herlenius,1 J. Mölne,2 L. Rydberg,3 O. Samuelsson,4 W. Bennet.1

    1Transplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden; 2Department of Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden; 3Department of Clinical Chemistry and Transfusion Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden; 4Department of Nephrology, Sahlgrenska University Hospital, Gothenburg, Sweden.

    IntroductionOne way to expand the donor pool for patients with acute liver failure could be to use deceased donor (DD) ABO-incompatible (ABOi) liver grafts. However,…
  • 2016 American Transplant Congress

    Association of Smoking Habits with Comorbidity 15 Years After Liver Transplantation.

    S. Pischke,3 M. Lege,1 L. Fischer,2 U. Herden,2 A. Lohse,3 B. Nashan,2 M. Sterneck.1

    1University Transplant Center, University Hospital Hamburg Eppendorf, Hamburg, Germany; 2Department of Hepatobiliary Surgery and Transplantation, University Hospital Hamburg Eppendorf, Hamburg, Germany; 3Department of Medicine, University Hospital Hamburg Eppendorf, Hamburg, Germany.

    Background and aimsThe survival rate of liver transplant (OLT) recipients has strongly improved over the last years. Here we investigate the association between long term…
  • 2016 American Transplant Congress

    Experience of Short-Term Preemptive Treatment for Cytomegalovirus Infection in Seropositive Patients After Liver Transplantation – Ten Years Result of a Single Institution.

    T.-J. Wu, Y.-C. Wang, C.-H. Cheng, T.-H. Wu, R.-S. Soong, C.-F. Lee, H.-S. Chou, K.-M. Chan, W.-C. Lee.

    Division of Liver and Transplantation Surgery, Department of General Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.

    Background/purpose Cytomegalovirus (CMV) infection remains a challenge following liver transplantation. Preemptive treatment is an effective strategy for CMV infection. This report shares the ten years'…
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