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American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Pediatric Kidney Transplantation and Mortality: Distance to Transplant Center Matters.

    J. Adler, Y. Bababekov, J. Markmann, D. Chang, H. Yeh.

    Surgery, Massachusetts General Hospital, Boston, MA.

    INTRODUCTION: The distance traveled by adults to kidney transplant centers contributes to disparities in access and outcomes. We hypothesized that distance would adversely affect the…
  • 2016 American Transplant Congress

    Low Pretransplant BMI/Weight and Changes in Posttransplant T Cell Exhaustion Levels Are Associated with Viremia/Viral Infection in Pediatric Kidney Transplantation in the First Post-Transplant Year – A Report from the IMPACT Study Consortium.

    R. Ettenger,1 H. Chin,2 P. Grimm,3 K. Kesler,2 E. Reed,4 M. Sarwal,5 B. Warshaw,6 E. Tsai,1 A. Kirk.7

    1Pediatrics, UCLA, LA, CA; 2Rho, Chappel Hill, NC; 3Pediatrics, Stanford Univ, Palo Alto, CA; 4Pathology, UCLA, LA, CA; 5Surgery, UCSF School of Medicien, SF, CA; 6Pediatric Nephrolgoy, Children's Healthcare of Atlanta, Atlanta, GA; 7Surgery, Duke University, Durham, NC.

    Viral consequences of immunosuppression (IS) in pediatric(ped)kidney(kid)transplantation(Tx)patients(pts) are not fully known. We prospectively examined the immunologic and infectious (inf) history of 106 ped Tx pts…
  • 2016 American Transplant Congress

    The Effect of Bortezomib on DSA Reduction During the Treatment of AMR in Pediatric Kidney Transplant Patients.

    O. Moussa, S. Self, K. Twombley.

    Medical University of South Carolina, Charleston, SC.

    Introduction: The optimal therapy for AMR is not well defined in children or adults. AMR carries a worse prognosis than ACR and can lead to…
  • 2016 American Transplant Congress

    Differences in Reported Barriers to Immunosuppression Adherence Among a Cohort of Pediatric Renal Transplant Recipients from the United States and Canada.

    O. Bignall II,1,2 A. Pai,2 S. Amaral,3 S. Furth,3 N. Bergman,2 J. Goebel,4 The TAKE-IT Study Investigators, B. Foster.5

    1Nephrology and Hypertension, Cincinnati Children's Hospital, Cincinnati, OH; 2Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital, Cincinnati, OH; 3Nephrology, The Children's Hospital of Philadelphia, Philadelphia, PA; 4Nephrology, Children's Hospital of Colorado, Aurora, CO; 5Nephrology, Montreal Children's Hospital, Montreal, QC, Canada.

    Aim: The purpose of this study was to examine differences in reported barriers to immunosuppressant adherence (IA) between a cohort of pediatric renal transplant recipients…
  • 2016 American Transplant Congress

    Donor-Specific Antibodies in a Single-Center Pediatric Kidney Transplant Population – Incidence and Risk Factors.

    M. Bock,1 L. Starkey,1 C. Buchanan,2 E. Steinberg,2 A. Sikora,2 K. McKinnon,2 M. Wachs,2 J. Goebel.1

    1Transplant Surgery, Children's Hospital Colorado, Aurora, CO; 2Pediatric Nephrology, Children's Hospital Colorado, Aurora, CO.

    In mid-2015, we implemented donor-specific antibody (DSA) monitoring in our pediatric kidney transplant recipient (pKTR) population as recommended (Transplantation 2013;95:19-). We now cross-sectionally analyzed our…
  • 2016 American Transplant Congress

    Geographic Variability in Access to Transplant Centers for Children with End-Stage Renal Disease.

    C. Toro,1 M. Ross,1,2 D. Wiebe,2 S. Amaral.1,2

    1Pediatrics, The Children's Hospital of Phila, Philadelphia, PA; 2Biostatistics and Epidemiology, The University of Pennsylvania, Philadelphia, PA.

    Background: Kidney transplantation is the optimal treatment for pediatric end-stage renal disease (ESRD); yet, there is substantial variability in waiting times for deceased donor kidneys…
  • 2016 American Transplant Congress

    Incidence of Post-Transplant Cardiovascular Disease After Pediatric Kidney Transplantation.

    O. Serrano,1 A. Bangdiwala,2 D. Vock,2 W. Payne,1 T. Dunn,1 S. Chinnakotla,1 E. Finger,1 R. Kandaswamy,1 T. Pruett,1 A. Matas,1 B. Chavers.3

    1Surgery, Univ. of Minnesota, Minneapolis, MN; 2Biostatistics, Univ. of Minnesota, Minneapolis, MN; 3Pediatrics, Univ. of Minnesota, Minneapolis, MN.

    PURPOSE: Kidney transplant (KTx) recipients have increased risk of cardiovascular disease (CVD), related to time on dialysis and post-KTx immunosuppression. To date, the incidence of…
  • 2016 American Transplant Congress

    Barriers to Living Donor Kidney Transplant in the Pediatric Population.

    S. Taormina,1 M. Galloway,2 A. Jain.3

    1Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI; 2Department of Psychiatry and Behavioral Neurosciences and Department of Anesthesiology, Wayne State University School of Medicine, Detroit, MI; 3Division of Pediatric Nephrology and Hypertension, Wayne State University School of Medicine, Detroit, MI.

    Objective:A shift from living donor transplants to deceased donor transplants has been noted nationwide and is more prominent at some centers than others. Our objective…
  • 2016 American Transplant Congress

    Benefit of Protocol Biopsies in Pediatric Kidney Transplant Patients.

    M. Nazario, O. Moussa, S. Self, K. Twombley.

    Medical University of South Carolina, Charleston.

    BackgroundMuch debate exists over the utility of protocol biopsies for pediatric kidney transplant recipients. While there is a growing amount of literature on the utility…
  • 2016 American Transplant Congress

    Influence of Donor and Recipient CYP3A4, CYP3A5 and ABCB1 Genotypes on Outcomes in Liver Transplants.

    M. Debette-Gratien,1 J. Woillard,2 N. Picard,2 M. Sebbagh,4 D. Sautereau,5 V. Loustaud-Ratti,1 D. Samuel,3 P. Marquet.2

    1Hepatology, INSERM UMR 850, Univ Limoges, CHU Limoges, Limoges, France; 2Pharmacology and Toxicology, INSERM UMR 850, Univ Limoges, CHU Limoges, Limoges, France; 3Hepatology, INSERM U785, Centre hépatobiliaire, Villejuif, France; 4Hepatology, Centre Hépatobiliaire, Villejuif, France; 5Hepatology, CHU Limoges, Limoges, France.

    Liver transplantation is a life-saving technique for patients with end-stage liver disease. Pharmacogenetics is promising to explain a part of variability of calcineurin inhibitors efficacy…
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