2016 American Transplant Congress
The Early Outcomes of Bortezomib Therapy in Patients with Late Antibody Mediated Rejection in Renal Transplantation.
Although several strategies for treating antibody mediated rejection (AMR) in renal transplants have been investigated, the formation of donor-specific antibodies (DSA) and ongoing AMR contribute…2016 American Transplant Congress
Graft Survival in Sensitized and Non-Sensitized Patients: Role of the Combination of Donor-Specific Antibodies and Acute Rejection.
Background: Sensitized (S) patients have higher risk for acute rejection (AR), especially ABMR. DSA is a risk fator for ABMR, however, its impact on AR…2016 American Transplant Congress
Alloimmunity Through Non-HLA Epitopes in Kidney Transplantation.
Introduction: An unexpected diversity in the human genome has been identified including more than 2,500 nonsynonymous single nucleotide polymorphisms (nsSNP) and up to 20 homozygous…2016 American Transplant Congress
Long Term Outcomes Following Antibody Mediated Rejection (AMR) in Renal Transplant Recipients.
Columbia University, New York.
INTRO: Progress in AMR treatment has improved early graft survival. Since the new kidney allocation system results in more sensitized patients getting transplanted, we expect…2016 American Transplant Congress
Elevation of Peripheral IL-6 in Kidney Transplant Recipients with Antibody Mediated Rejection.
University of Wisconsin, Madison.
Background: Despite current therapy, antibody mediated rejection (AMR) remains a major cause of kidney allograft loss. IL-6 is a known survival factor of antibody secreting…2016 American Transplant Congress
The Function of CD8+TCR– Facilitating Cells and Regulatory T Cells Is Impaired in Flt3-Ligand Knockout Mice.
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY.
Graft CD8+TCR- facilitating cells (FC) enhance engraftment of hematopoietic stem cells (HSC) in allogeneic mouse recipients without causing graft-versus-host disease. FC induce antigen-specific CD4+CD25+FoxP3+ regulatory…2016 American Transplant Congress
c-Kit+ Cells Are Kidney-Specific Progenitor/Stem Cells with Regenerative Potential.
Introduction: Identification of progenitor/stem cell populations in mammalian tissues is important for therapeutic applications and for understanding biological processes. We recently reported that c-Kit+ cells…2016 American Transplant Congress
CD8+TCR– Facilitating Cells in Mobilized Peripheral Blood Mononuclear Cells Are Enriched with IL-10 Producing B Cells.
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY.
We recently reported that facilitating cell (FC) enriched hematopoietic progenitor stem cell (HSPC) allografts (FCRx) induced tolerance without graft-versus-host disease (GVHD) or engraftment syndrome in…2016 American Transplant Congress
iNKT Cell Ligands Administered with Bone Marrow Cells Expand Allo-Specific Regulatory T Cells In Vivo and Establish Transplant Tolerance.
Invariant natural killer T(iNKT) cells have the powerful potential to expand regulatory T cells(Tregs), especially when they are presented α-galactosylceramide(aGC) by B cells. We previously…2016 American Transplant Congress
Improved Regeneration of the Remnant Liver After Extended Hepatectomy or Partial Liver Transplantation by Pharmacologic Mobilization of Endogenous Stem Cells in Rats.
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
BackgroundRapid regeneration of the remnant liver after extended partial hepatectomy or reduced size liver transplantation is essential to prevent small-for-size syndrome (SFSS). We hypothesize that…
American Transplant Congress abstracts