2016 American Transplant Congress
Role of Preformed IgM Donor Human Leucocyte Antigen (HLA) Specific Antibodies in HLA Incompatible Renal Transplantation.
Introduction: Pre-transplant IgG antibody screening is common due to its established role of predicting rejection and graft survival; the role of pre-formed IgM human leukocyte…2016 American Transplant Congress
Type of Sensitization Does Not Impact Kidney Graft Outcome in Weakly Sensitized Patients.
Introduction: The impact of low level sensitization on kidney transplant (KTx) outcomes is unclear. While limited data suggest that KTx outcomes are comparable between weakly…2016 American Transplant Congress
Diffuse Extent of Peritubular Capillaritis in Late Antibody Mediated Rejection Is Associated with More Severe Chronic Allograft Damage.
Peritubular capillaritis (ptc) is a widely accepted histologic criterion of antibody-mediated rejection (ABMR), and while the ptc score is incorporated in current diagnostic recommendations, the…2016 American Transplant Congress
The Impact of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx) Is Independent of Time Post-Transplant.
Detection of MVI in a KTxBx, often associated with antibody mediated rejection, is associated with a poor prognosis for kidney graft survival. However most information…2016 American Transplant Congress
Presence of Highly Immunogenic Mismatch Eplets Is Associated with Development of Chronic Active Antibody-Mediated Rejection: A First Report from Japan.
Urology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
Backgrounds: De novo donor specific antibody (dnDSA) correlates with chronic active antibody-mediated rejection (CAAMR), a major leading cause of graft loss. It will be a…2016 American Transplant Congress
Factors Mediating Kidney Rejection in Patients of Simultaneous Liver-Kidney Transplants.
BACKGROUND & AIM: Kidney grafts in simultaneous liver-kidney (SLK) recipients are considered to be immunologically protected due to hepatic tolerance, although recent studies have alternatively…2016 American Transplant Congress
Kidney Transplantation with Strong Preformed Donor-Specific Antibodies: Impact of C1q-Binding Ability.
1Nephrology, CHP, Porto, Portugal; 2CSTP, Porto, Portugal.
HLA-incompatible kidney transplantation is associated with worse outcomes given the presence of donor-specific anti-HLA antibodies (DSA). Our aim was to investigate the association between preformed…2016 American Transplant Congress
The Prediction of Molecular ABMR by Anti-HLA Donor-Specific Antibody Properties.
Study purpose: Besides HLA antibody characterization and workup of biopsies (Bx) molecular assessment of gene expression may considerably improve ABMR diagnosis. The objective of the…2016 American Transplant Congress
Expansion of Anti-HLA Antibodies After Renal Transplantation and Prognosis in Those Which Fix C1q.
Introduction. Antibody-mediated rejection (ABMR) is the major cause of allograft failure. We studied the evolution and prognostic effect of pre-formed and de novo anti-HLA antibodies…2016 American Transplant Congress
The Effect of Tocilizmab Treatment (TCZ-Rx) on Total IgG and Anti-CMV-IgG Levels in HLA-Sensitized (HS) Kidney Transplant Patients.
Background: TCZ has anti-B cell and anti-inflammatory properties. We have reported its successful use for pre-transplant (Tx) desensitization (DES) and treatment of ABMR. We also…
American Transplant Congress abstracts