2016 American Transplant Congress
Evaluation of the Impact of the Implementation of a Specialty Pharmacy Program in the Treatment of Hepatitis C (HCV).
Aurora St Luke's Medical Center, Milwaukee, WI.
Background: Current guidelines recommend newer therapies over previous interferon-based treatments. The creation of a specialty pharmacy program within our institution that provides managed care for…2016 American Transplant Congress
Parameters of Uremia-Associated Premature Ageing of Peripheral T Cells Do Not Predict Infectious Complications After Renal Transplantation.
Background: End-stage renal disease (ESRD) patients have a prematurely aged T-cell system, which may contribute to the uremia-associated immune deficiency. In this study we tested…2016 American Transplant Congress
Direct Detection of T and B Memory Lymphocytes Reveals HCMV Exposure That Serum Antibodies Fail to Identify.
Research and Development, Cellular Technology Ltd, Shaker Hts, OH.
It is essential to identify donors who have not been infected with HCMV in order to avoid transmission of HCMV to human recipients of transfusion…2016 American Transplant Congress
Assessment of mRNA Gene Profiles in Plasma Exosome to Predict Risk for Antibody-Mediated Rejection (ABMR) of Renal Allografts.
Background: ABMR is a major obstacle for successful transplant in HLA-sensitized (HS) patients. Complement-mediated and antibody-dependent cellular cytotoxicity (ADCC) are primarily mechanisms for ABMR. Previously…2016 American Transplant Congress
Predicting the Ability of Anti-HLA Antibodies to Activate Complement.
Purpose: The single antigen bead (SAB) assay measures binding of antibodies (Abs) to HLA in units of mean florescence intensity (MFI). Two assays measure the…2016 American Transplant Congress
HCV, Acute Rejection, and the New Direct-Acting Antivirals in Deceased Donor Kidney Transplant Recipients.
The association between hepatitis C virus (HCV) seropositivity and acute rejection (AR) in kidney transplant donors and recipients is unclear, and may have changed with…2016 American Transplant Congress
The Phenotypic Diversity of Late Silent Antibody-Mediated Rejection.
Study purpose: ABMR is a driving force of long-term allograft loss in organ transplantation. The present study was designed to characterize the phenotypic diversity of…2016 American Transplant Congress
The Combined Effect of Acute Rejection and De Novo Donor-Specific Antibodies on Kidney Allograft Survival.
Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO.
While dnDSA is associated with graft loss in multiple studies, the clinical context in which dnDSA develops and contributes to graft loss is less well…2016 American Transplant Congress
Digital Kidney Biopsy Evaluation: Quantification of Macrophage Prevalence in a Cross Sectional Study.
Standardized markers based on quantitative and qualitative evaluation of immune cell mass and localization in kidney biopsies may help in diagnosis and prognosis in transplantation…2016 American Transplant Congress
Enhanced Natural Killer Responsiveness Is a Potent Cytotoxic Mechanism Associating to Kidney Allograft Dysfunction and Pathogenic Effects of Donor-Specific Antibodies (DSA).
While antibody mediated rejection (ABMR) is a major cause of kidney transplant loss, the role of Natural Killer cells (NK) as immune effectors of complement-independent…
American Transplant Congress abstracts