ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Transplant Coordinator Time Saved (TCTS) Through a Hybrid On Call Team for Deceased Donor Kidney and Pancreas Transplant Organ Offers

    K. Ko, C. Gregory, J. Le, A. Lutrick, U. Reddy

    Division of Kidney and Pancreas Transplantation, UC Irvine, Orange, CA

    *Purpose: The purpose of this analysis was to estimate transplant coordinator time saved (TCTS) through the implementation of a hybrid on call team. Historically, transplant…
  • 2022 American Transplant Congress

    An Acceptable Challenge for Specialized Transplant Centres: Small Kidney Donors for Small Recipients

    R. Büscher, M. Cetiner, P. F. Hoyer, A. K. Büscher

    Department of Pediatrics II, University Hospital Essen, Essen, Germany

    *Purpose: Kidneys from small donors (SDK, donor weight
  • 2022 American Transplant Congress

    Single Kidney Transplantation Using Pediatric Donor Kidneys: Satisfactory Outcomes but Specific Attentions Needed

    M. Huang, W. Wu, X. Su, J. Li, C. Wu, H. Zhang, Q. Fu, J. Li, S. Wu, Y. Chen, Q. Zhang, L. Liu, C. Wang

    The First Affiliated Hospital Of Sun Yat-sen University, Guangzhou, China

    *Purpose: Utilization of pediatric donor in single kidney transplantation (SKT) are popular and can greatly expand the scarce donor pool, whereas potential risk factors remain…
  • 2022 American Transplant Congress

    COVID-19 Vaccination Induces a Poor Interleukin-21 Memory T-cell Response in Kidney Transplant Recipients

    S. R. Malahe1, Y. den Hartog1, R. de Kuiper1, D. Reijerkerk1, D. Geers2, C. H. GeurtsvanKessel2, M. M. Kho1, R. D. de Vries2, M. E. Reinders1, C. C. Baan1

    1Internal Medicine, Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands, 2Viroscience, Erasmus MC, Rotterdam, Netherlands

    *Purpose: COVID-19-related morbidity and mortality is high among kidney patients. Several studies recently suggested low humoral and cellular immune responses after two doses of mRNA-1273…
  • 2022 American Transplant Congress

    Utilization and Discard of Organs from Covid -19 Infected Donors: A Us National Registry Analysis

    A. Azhar1, I. Moinuddin1, A. B. Gungor2, M. K. Morales1, M. Z. Molnar3, B. Tanriover2, G. Gupta1

    1Virginia Commonwealth University, Richmond, VA, 2University of Arizona, Tuscon, AZ, 3University of Utah, Salt Lake City, UT

    *Purpose: Expansion of the donor pool remains a major unmet need for solid organ transplants (SOT). Early data suggests that at least some severe acute…
  • 2022 American Transplant Congress

    Pregnancy After Heart Transplant Does Not Negatively Impact Long Term Patient Survival

    M. J. Moritz1, D. Lee2, C. Madu2, S. Hossain3, L. A. Coscia4, S. Rao5, S. Constantinescu6

    1Surgery, Lehigh Valley Health Network, Allentown, PA, 2Cardiovascular Medicine, University of South Florida, Morsani College of Medicine, Tampa, FL, 3Data Analytics, University of South Florida, Muma College of Business, Tampa, FL, 4Transplant Pregnancy Registry International, Philadelphia, PA, 5Nephrology, University of Virginia Health System, Charlottesville, VA, 6Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA

    *Purpose: To evaluate the impact of pregnancy on patient survival in heart transplant recipients (HTRs), we linked the Transplant Pregnancy Registry International (TPRI) dataset with…
  • 2022 American Transplant Congress

    Validation of a Hypertension Risk Calculator for Living Kidney Donors

    E. S. Helgeson1, S. Vempati1, E. F. Palzer1, G. Mjøen2, A. J. Haugen3, A. Matas4

    1Division of Biostatistics, University of Minnesota, Minneapolis, MN, 2Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, 3Department of Internal Medicine, Bærum Hospital, Sandvika, Norway, 4Department of Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: It would be ideal if candidates considering kidney donation understood their long-term risks. Using single-center data (n=4055; median [IQR] f/u: 18 [9-28] yrs), we…
  • 2022 American Transplant Congress

    Semaglutide Tolerability and Efficacy in Patients with Chronic Kidney Disease Stage 4, 5 and End Stage Renal Disease

    J. J. Long, A. Lemke, V. Sudhindran, N. Pencovici, A. Kukla, T. Diwan

    Mayo Clinic, Rochester, MN

    *Purpose: Obesity is often a barrier to kidney transplantation (KT) due to increased perioperative risks and worse outcomes with many transplant centers setting BMI cut…
  • 2022 American Transplant Congress

    Leveraging Single-Cell Signatures in Kidney Transplant Biopsies Uncovers Immunological Heterogeneity Within Rejection Phenotypes

    J. Callemeyn1, B. Lamarthée1, P. Koshy2, T. Debyser3, E. Van Loon1, A. Franken4, T. Van Brussel4, I. Arijs4, D. Lambrechts4, M. Rabant5, A. Senev1, T. Vaulet6, C. Tinel1, M. Naesens1

    1Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 2Department of Morphology and Molecular Pathology, University Hospitals Leuven, Leuven, Belgium, 3Faculty of Medicine, KU Leuven, Leuven, Belgium, 4Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium, 5Necker-Enfants Malades Institute, Institut national de la santé et de la recherche médicale (Inserm), Université de Paris, Paris, France, 6ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium

    *Purpose: Rejection of the kidney allograft is hallmarked by the accumulation of inflammatory cells within the renal architecture, leading to microvascular or tubulointerstitial inflammation. However,…
  • 2022 American Transplant Congress

    Rhesus-Primatized Mouse Model Generated Using Transgenic Immunodeficient Mice

    C. Little1, W. J. Haynes1, L. Huang1, C. Daffada1, K. B. Wolfe2, E. Perrin2, J. A. Simpson1, J. A. Kropp Schmidt2, H. M. Hinkle2, L. T. Keding2, R. T. Behrens2, D. T. Evans2, D. Kaufman1, J. A. Thomson2, T. G. Golos2, M. Brown1

    1Surgery, University of Wisconsin, Madison, WI, 2University of Wisconsin, Madison, WI

    *Purpose: To develop a translational primatized mouse model, akin to humanized mice, that allows for high-throughput in vivo experimentation to augment non-human primate pre-clinical studies.*Methods:…
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