ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Patient-Reported Physical Function Correlates with Liver Frailty Index and 4-Meter Gait Speed in Patients with Cirrhosis

    A. J. Thuluvath, J. Peipert, K. Belfanti, S. Morrissey, O. Siddiqui, J. Levitsky, Z. Dietch, A. Flores, D. P. Ladner

    Northwestern University Feinberg School of Medicine, Chicago, IL

    *Purpose: Frailty is highly prevalent in patients with end-stage liver disease and strongly predicts waitlist and post-transplant mortality. The Liver Frailty Index (LFI) and 4-meter…
  • 2022 American Transplant Congress

    Evaluation of Diabetes-Free Life Expectancy Among Living Kidney Donors and Non-Donors with Obesity: A Longitudinal Cohort Study

    C. Killian1, R. Reed1, M. McLeod1, P. MacLennan1, V. Kumar1, S. Brooks1, A. Maynor1, L. Stanford1, G. Baker1, C. Schinstock2, J. Silkensen3, G. Roll4, D. Segev5, B. Orandi1, C. Lewis1, J. Locke1

    1University of Alabama at Birmingham, Birmingham, AL, 2Mayo Clinic, Rochester, MN, 3Hennepin County Medical Center, Minneapolis, MN, 4UCSF Medical Center, San Francisco, CA, 5Johns Hopkins University, Baltimore, MD

    *Purpose: The growing end stage kidney disease burden paired with substantial rates of obesity in the United States (US) has prompted increased approval of obese…
  • 2022 American Transplant Congress

    Transjugular Intrahepatic Portosystemic Shunt Placement is Associated with Increased All-Cause and Cardiac Mortality in Those Undergoing Liver Transplant for Nonalcoholic Steatohepatitis

    D. U. Lee1, J. Han2, J. Kwon2, K. Chang2, G. Fan2, K. Lee1, N. Urrunaga3, C. Bhati1, D. Maluf3, K. Shetty3

    1Department of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, 2Tufts Medical Center, Boston, MA, 3University of Maryland, Baltimore, MD

    *Purpose: Since the effect of transjugular intrahepatic portosystemic shunt (TIPS) on post LT outcomes is not well understood, we undertook this analysis of a large…
  • 2022 American Transplant Congress

    Creating a Workflow for the Electronic Medical Record Allows Living Donor Liver Transplantation Programs to Track Candidates and Identify Areas for Optimization

    A. Liapakis1, R. Batra1, E. Cohen2, D. Haakinson1, M. Schilsky1, K. Ventura2, D. Mulligan1

    1Yale University School of Medicine, New Haven, CT, 2Yale New Haven Hospital, New Haven, CT

    *Purpose: To provide a pathway to increase living donor liver transplantation (LDLT) opportunities through creation of a simple workflow algorithm embedded within the EPIC electronic…
  • 2022 American Transplant Congress

    Comparison of Immediate-Release Tacrolimus to Envarsus XR on the Development of Donor Specific Antibodies in Kidney Transplant Recipients

    R. A. Arora, C. Kane, K. Lang, M. Kapugi, C. D'Agostino, K. Cunningham, S. H. Park

    Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Major causes of de novo development of donor specific antibodies (DSA) after kidney transplant include medication noncompliance and immunosuppression minimization or elimination that may…
  • 2022 American Transplant Congress

    Focal Distribution of TCMR Causes False Negative Results in Spatially Resolved Molecular Diagnostic Assays

    P. Randhawa, Y. Huang

    University of Pittsburgh, Pittsburgh, PA

    *Purpose: Molecular assays on ~3mm biopsy (BX) fragments of cannot confirm histologic T-cell mediated rejection (TCMR) in ~50% of routine biopsies, and fail to detect…
  • 2022 American Transplant Congress

    Long-Term Outcomes of Crossmatch Positive Simultaneous Liver Kidney Transplants in the United States

    S. Riad1, E. Aby1, S. Jackson2, P. Nguyen3, N. Lim1, J. Lake1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Mhealth-Fairview, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: The long-term results of crossmatch positive (XM+) simultaneous liver-kidney (SLK) transplants are conflicting. We examined the association between crossmatch (XM) status and SLK outcomes…
  • 2022 American Transplant Congress

    Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)

    D. J. Reich1, A. Schlegel2, M. Rizzari3, D. Foley4, M. DeVera5, W. Chapman6, G. Roll7, A. Saharia8, C. Quintini9, S. Florman10, S. Merani11, S. Mao12, A. Pinna13, M. Akoad14, C. Kubal15, S. Alexopoulos16, H. Bohorquez17

    1Drexel University, Philadelphia, PA, 2Careggi U, Florence, Italy, 3Henry Ford, Detroit, MI, 4U Wisconsin, Madison, WI, 5Loma Linda, Loma Linda, CA, 6Washington U, Saint Louis, MO, 7UCSF, SF, CA, 8Methodist, Houston, TX, 9Cleveland Clinic, Cleveland, OH, 10Mount Sinai, NY, NY, 11U Nebraska, Omaha, NE, 12Mayo, Jacksonville, FL, 13Cleveland Clinic, Weston, FL, 14Lahey, Burlington, MA, 15Indiana U, Indianapolis, IN, 16Vanderbilt, Nashville, TN, 17Ochsner, New Orleans, LA

    *Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…
  • 2022 American Transplant Congress

    Better Antibody Response After a Dose of Ad.26.cov2.s vs MRNA Vaccines in Seronegative Transplant Recipients After 2-Dose MRNA Vaccination

    J. L. Alejo1, T. Chiang1, J. Mitchell1, A. Abedon1, L. Thomas1, A. Chang1, S. Bae1, R. Avery1, A. Tobian1, A. Massie1, M. Levan1, D. Warren1, J. Garonzik-Wang2, D. Segev1, W. Werbel1

    1JHU, Baltimore, MD, 2U of Wisconsin, Madison, WI

    *Purpose: To compare antibody response to a third dose (D3) of SARS-CoV-2 vaccine in solid organ transplant recipients (SOTRs) with negative or low-positive antibody levels…
  • 2022 American Transplant Congress

    Gender Affects the Association Between Serum Creatinine Levels and Clinical Response to Terlipressin in Patients with Hepatorenal Syndrome Type of Acute Kidney Injury

    K. Jamil1, R. Frederick2, S. Pappas3

    1Hepatology, Mallinckrodt Pharmaceuticals, Clinton, NJ, 2Liver Disease/Hepatology & Transplant Hepatology, California Pacific Medical Center, San Francisco, CA, 3Orphan Therapeutics, LLC, Longboat Key, FL

    *Purpose: Hepatorenal syndrome (HRS)-acute kidney injury (AKI) is a rare and serious complication of cirrhosis, with serum creatinine (SCr) used diagnostically. Women generally have less…
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