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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Variation in Adult Living Donor Liver Transplantation in the United States: Identifying Opportunities for Increased Utilization

    K. Lentine1, D. Axelrod2, M. Schnitzler1, R. Li1, M. Dew3, T. Bitterman4, K. Olthoff4, J. Locke5, S. Emre6, H. Hunt7, T. Tanaka2, A. Liapakis6

    1Saint Louis University, St. Louis, MO, 2U Iowa, Iowa City, IA, 3U Pittsburgh, Pittsburgh, PA, 4U Penn, Philadelphia, PA, 5UAB, Birmingham, AL, 6Yale, New Haven, CT, 7UNOS, Richmond, VA

    *Purpose: To assess barriers to living donor liver transplant (LDLT) access in light of convincing evidence of survival benefits for patients with end-stage liver disease.*Methods:…
  • 2022 American Transplant Congress

    Validation of a Hypertension Risk Calculator for Living Kidney Donors

    E. S. Helgeson1, S. Vempati1, E. F. Palzer1, G. Mjøen2, A. J. Haugen3, A. Matas4

    1Division of Biostatistics, University of Minnesota, Minneapolis, MN, 2Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, 3Department of Internal Medicine, Bærum Hospital, Sandvika, Norway, 4Department of Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: It would be ideal if candidates considering kidney donation understood their long-term risks. Using single-center data (n=4055; median [IQR] f/u: 18 [9-28] yrs), we…
  • 2022 American Transplant Congress

    Better Antibody Response After a Dose of Ad.26.cov2.s vs MRNA Vaccines in Seronegative Transplant Recipients After 2-Dose MRNA Vaccination

    J. L. Alejo1, T. Chiang1, J. Mitchell1, A. Abedon1, L. Thomas1, A. Chang1, S. Bae1, R. Avery1, A. Tobian1, A. Massie1, M. Levan1, D. Warren1, J. Garonzik-Wang2, D. Segev1, W. Werbel1

    1JHU, Baltimore, MD, 2U of Wisconsin, Madison, WI

    *Purpose: To compare antibody response to a third dose (D3) of SARS-CoV-2 vaccine in solid organ transplant recipients (SOTRs) with negative or low-positive antibody levels…
  • 2022 American Transplant Congress

    Transplant Coordinator Time Saved (TCTS) Through a Hybrid On Call Team for Deceased Donor Kidney and Pancreas Transplant Organ Offers

    K. Ko, C. Gregory, J. Le, A. Lutrick, U. Reddy

    Division of Kidney and Pancreas Transplantation, UC Irvine, Orange, CA

    *Purpose: The purpose of this analysis was to estimate transplant coordinator time saved (TCTS) through the implementation of a hybrid on call team. Historically, transplant…
  • 2022 American Transplant Congress

    Utilization and Discard of Organs from Covid -19 Infected Donors: A Us National Registry Analysis

    A. Azhar1, I. Moinuddin1, A. B. Gungor2, M. K. Morales1, M. Z. Molnar3, B. Tanriover2, G. Gupta1

    1Virginia Commonwealth University, Richmond, VA, 2University of Arizona, Tuscon, AZ, 3University of Utah, Salt Lake City, UT

    *Purpose: Expansion of the donor pool remains a major unmet need for solid organ transplants (SOT). Early data suggests that at least some severe acute…
  • 2022 American Transplant Congress

    Renal Failure is Reversible in the Majority of Patients Transplanted for Alcohol-Associated Hepatitis: A Review of the UNOS Database

    Y. Bekki, G. Im, T. Schiano, S. Florman

    Icahn School of Medicine at Mount Sinai, RMTI, New York, NY

    *Purpose: The simultaneous liver-kidney (SLK) allocation policy in 2017 created Safety Net kidney allocation priority for liver transplant (LT) recipients with renal failure. Renal failure…
  • 2022 American Transplant Congress

    Non-HLA Antibodies to G Protein-Coupled Receptors and Allograft Survival in Pediatric Kidney Transplant Recipients: Short- and Long-Term Outcomes

    M. Pearl1, L. Chen1, P. Weng1, E. T. Chambers2, E. F. Reed3

    1UCLA, Los Angeles, CA, 2Pediatrics, Duke University, Durham, NC, 3Univ of California LA, Los Angeles, CA

    *Purpose: We have recently shown that the non-HLA antibodies to angiotensin II type 1 receptor (AT1R-Ab) and endothelin-1 type A receptor (ETAR-Ab) are prevalent and…
  • 2022 American Transplant Congress

    Differentially Methylated Genes Predict Post-Transplant Relapse of Unresectable Hepatoblastoma

    M. Ningappa1, M. Muarya2, C. Ashokkumar1, H. Hakonarson3, S. Subramaniam4, R. Sindhi1

    1Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2Department of Bioengineering & San Diego Supercomputer Center, University of California, San Diego, CA, 3Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 4Department of Computer Science and Engineering, and Nanoengineering, University of California, San Diego, La Jolla, CA

    *Purpose: Hepatoblastoma (HB), a developmental liver tumor of childhood requires liver transplantation (LT) if it remains unresectable despite chemotherapy. Post-transplant relapse in up to 20%…
  • 2022 American Transplant Congress

    Leveraging Single-Cell Signatures in Kidney Transplant Biopsies Uncovers Immunological Heterogeneity Within Rejection Phenotypes

    J. Callemeyn1, B. Lamarthée1, P. Koshy2, T. Debyser3, E. Van Loon1, A. Franken4, T. Van Brussel4, I. Arijs4, D. Lambrechts4, M. Rabant5, A. Senev1, T. Vaulet6, C. Tinel1, M. Naesens1

    1Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 2Department of Morphology and Molecular Pathology, University Hospitals Leuven, Leuven, Belgium, 3Faculty of Medicine, KU Leuven, Leuven, Belgium, 4Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium, 5Necker-Enfants Malades Institute, Institut national de la santé et de la recherche médicale (Inserm), Université de Paris, Paris, France, 6ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium

    *Purpose: Rejection of the kidney allograft is hallmarked by the accumulation of inflammatory cells within the renal architecture, leading to microvascular or tubulointerstitial inflammation. However,…
  • 2022 American Transplant Congress

    Experience Using Intra-Operative Dialysis in Surgically Complex Liver Transplantation

    M. Palascak1, D. Arango1, S. Yockelson1, J. Koveleskie1, D. Ganier1, A. Cohen2, H. Bohorquez2

    1Anesthesiology, Ochsner, New Orleans, LA, 2Surgery, Ochsner, New Orleans, LA

    *Purpose: At our high-volume center, we often perform liver transplantation (LT) on surgically complex patients that includes re-transplantation, prior open liver resection, bariatric surgeries, extensive…
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