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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    BMI Trajectory and Attributable Risk of New Onset Hypertension Among Obese Living Kidney Donors

    R. D. Reed1, M. C. McLeod1, P. A. MacLennan1, V. Kumar1, S. E. Brooks1, A. G. Maynor1, L. A. Stanford1, G. A. Baker1, C. A. Schinstock2, J. R. Silkensen3, G. R. Roll4, D. L. Segev5, B. J. Orandi1, C. E. Lewis6, J. E. Locke1

    1Surgery, University of Alabama at Birmingham, Birmingham, AL, 2Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 3Medicine, Hennepin County Medical Center, Minneapolis, MN, 4Surgery, University of California San Francisco, San Francisco, CA, 5Surgery, Johns Hopkins University, Baltimore, MD, 6Epidemiology, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Obesity increases hypertension risk in general and living kidney donor populations. Risk attributable to donation in the context of obesity and whether that risk…
  • 2022 American Transplant Congress

    Kidney Transplant Alone Recipients with Advanced Liver Disease Have Similar Outcomes to Those without Advanced Liver Disease

    R. R. Nathani, S. M. Rutledge, C. Villarroel, R. Shapiro, G. Y. Im

    Icahn School of Medicine at Mount Sinai, New York, NY

    *Purpose: The prevalence of concomitant liver disease (CLD) in patients with ESRD is reported to be 7-40%. Safety of kidney transplant alone (KTA) in those…
  • 2022 American Transplant Congress

    Digital Spatial Profiling of Kidney Allograft Biopsies with Chronic Allograft Dysfunction in African American Transplant Recipients

    C. R. Dorr1, S. A. Elmer1, B. Wu2, B. Guo2, J. Czyzyk2, G. Crary3, G. Onyeaghala1, W. Oetting2, P. Jacobson2, R. B. Mannon4, G. Agarwal5, J. Maltzman6, A. Matas2, A. Israni3

    1Hennepin Healthcare Research Institute, Minneapolis, MN, 2University of Minnesota, Minneapolis, MN, 3Hennepin County Medical Center, Minneapolis, MN, 4Medicine, University of Nebraska Medical Center, Omaha, NE, 5University of Alabama at Birmingham, Birmingham, AL, 6Stanford University, Palo Alto, CA

    *Purpose: Understanding tissue heterogeneity is important to identify the molecular and cellular mechanisms of kidney allograft loss in African American (AA) transplant recipients. Our aim…
  • 2022 American Transplant Congress

    A Novel Application of SRTR Data to Interrogate the Effects of HLA-DQ Mismatches in Kidney Transplantation

    D. Isaacson1, M. W. Gmeiner2, V. Kosmoliaptsis3, H. C. Copley3, J. D. Schold4, A. R. Tambur1

    1Northwestern University, Chicago, IL, 2London School of Economics, London, United Kingdom, 3Cambridge University, Cambridge, United Kingdom, 4Cleveland Clinic, Cleveland, OH

    *Purpose: Single-center studies demonstrate de-novo HLA-DQ donor-specific antibodies (DSA) are the most common and pathogenic DSA. However, HLA-DQ is not accounted for in many kidney…
  • 2022 American Transplant Congress

    Social Determinants of Health Impact Successful Listing for Liver and Kidney Transplant

    J. B. Henson, D. Mohottige, J. M. Wilder, A. J. Muir, L. M. McElroy

    Duke University, Durham, NC

    *Purpose: To evaluate the association between community socioeconomic disadvantage and structural social determinants of health (SDOH) on successful listing for liver (LT) and kidney transplantation…
  • 2022 American Transplant Congress

    Cmv-Specific Cell-Mediated Immune Reconstitution in High-Risk Hematopoietic Cell Transplant Recipients Receiving Letermovir Prophylaxis

    M. Z. Abidi1, K. Garth1, J. Gutman2, A. Weinberg1

    1Medicine, Infectious Disease, University of Colorado, Aurora, CO, 2Medicine, Hematology and Oncology, University of Colorado, Aurora, CO

    *Purpose: In the absence of antiviral prophylaxis following Hematopoietic Cell Transplant (HCT), the incidence of clinically significant cytomegalovirus reactivation (cCMV) is 30% in CMV seropositive…
  • 2022 American Transplant Congress

    Characterizing the Landscape of Cancer Risk Following HLA-Incompatible Living Donor Kidney Transplantation

    J. D. Motter1, K. Jackson1, K. Yu2, R. M. Pfeiffer2, A. Massie1, J. Garonzik-Wang3, D. Segev1, E. A. Engels2

    1Johns Hopkins University, Baltimore, MD, 2National Cancer Institute, Bethesda, MD, 3University of Wisconsin-Madison, Madison, WI

    *Purpose: Incompatible living donor kidney transplant recipients (ILDKTr) require desensitization to facilitate transplantation across donor-specific antibody (DSA); however, this substantial upfront immunosuppression may result in…
  • 2022 American Transplant Congress

    Individual and Community-Level Social Determinants of Health in Liver Transplant

    M. Yilma1, R. Cogan2, N. Mehta3, J. Neuhaus2, J. Voelkel4, C. Light5, I. Allen2, R. Hirose2

    1General Surgery, University of California, San Francisco, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA, 3UCSF, San Francisco, CA, 4Kaiser Permanente Northern California, San Francisco, CA, 5UCSF Medical Center, San Francisco, CA

    *Purpose: To investigate the individual and census-level social determinants of health on liver transplant listing.*Methods: Retrospective review of patients referred to the University of California…
  • 2022 American Transplant Congress

    Liver Transplant Outcomes Using Grafts with Early Allograft Dysfunction

    S. Y. Ohara1, E. Macdonough2, G. Mahdi3, L. Egbert3, B. Lizaola-Mayo2, W. Hewitt4, A. Mathur4, A. Moss4, K. Reddy4, B. Aqel4, C. Jadlowiec4

    1Division of Surgery, Valleywise Health Medical Center, Creighton University, Phoenix, AZ, 2Division of Gastroenterology and Hepatology, Mayo Clinic Arizona, Phoenix, AZ, 3Mayo Clinic Alix School of Medicine, Phoenix, AZ, 4Division of Transplant Surgery, Mayo Clinic Arizona, Phoenix, AZ

    *Purpose: The significance of early allograft dysfunction (EAD) and its impact on liver transplant (LT) outcomes remains debated. Our study aimed to assess LT outcomes…
  • 2022 American Transplant Congress

    Is a Single Dose of Steroids in Adult Living Donor Liver Transplant Safe? – A Cohort Analysis

    M. Nunez, C. Praglin, A. M. Torres, E. Agudelo, H. Braun, C. Huang, S. Syed, J. Roberts, G. Roll

    University of California San Francisco, San Francisco, CA

    *Purpose: Steroids increase morbidity, and steroid avoidance (SA) has been studied in deceased donor liver transplant but, little is known about SA in living donor…
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