ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Establishing a Framework for Long-Term Follow-Up: A Survey of Perspectives and Preferences of Living Kidney Donors

    S. K. Singh1, N. Caton2, O. Johnston2, C. S. Hanson3, A. Dominello3, K. Yetzer4, D. Chang2, A. Tong3, J. S. Gill2

    1Department of Medicine, University of Toronto, Toronto, ON, Canada, 2Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 3Sydney School of Public Health, University of Sydney, Sydney, Australia, 4Canadian Blood Services, Ottawa, ON, Canada

    *Purpose: There is currently no established standard for long-term follow-up of living kidney donors in Canada. To inform a new national standard, we sought to…
  • 2022 American Transplant Congress

    Renal Failure is Reversible in the Majority of Patients Transplanted for Alcohol-Associated Hepatitis: A Review of the UNOS Database

    Y. Bekki, G. Im, T. Schiano, S. Florman

    Icahn School of Medicine at Mount Sinai, RMTI, New York, NY

    *Purpose: The simultaneous liver-kidney (SLK) allocation policy in 2017 created Safety Net kidney allocation priority for liver transplant (LT) recipients with renal failure. Renal failure…
  • 2022 American Transplant Congress

    Long-Term Outcomes for Living Kidney Donors with Early Guideline-Concordant Follow-Up Care

    A. Dhalla1, A. Lloyd2, K. L. Lentine3, A. X. Garg4, R. R. Quinn1, P. Ravani1, S. W. Klarenbach2, B. R. Hemmelgarn2, U. Ibelo1, N. N. Lam1

    1Department of Medicine, Division of Nephrology, University of Calgary, Calgary, AB, Canada, 2Department of Medicine, Division of Nephrology, University of Alberta, Edmonton, AB, Canada, 3Center for Abdominal Transplantation, Saint Louis University, St. Louis, MO, 4Department of Medicine, Division of Nephrology, Western University, London, ON, Canada

    *Purpose: Current guidelines recommend that living kidney donors receive annual lifelong follow-up to monitor kidney health. It is unclear whether early guideline-concordant care is associated…
  • 2022 American Transplant Congress

    Cognitive Bias in Transplant Surgery: A Qualitative Study of Transplant Clinicians in the United States

    K. Ladin1, J. Perry2, C. Eiduson3

    1REACH Lab, Tufts University, Medford, MA, 2Harvard University, Cambridge, MA, 3University of Rochester School of Medicine & Dentistry, Rochester, NY

    *Purpose: Clinicians’ judgments about patients’ social support often affect whether patients are listed for transplantation. Decision-making is thought to be based on two systems of…
  • 2022 American Transplant Congress

    Phase I/ii Car-Treg Cell Therapy Clinical Trial To Induce Long-term Tolerance In Liver Transplant Patients

    A. Sanchez-Fueyo1, A. Taylor1, D. Collin2, C. Nathalie2, S. Chris2, M. Martinez-Llordella2, N. Belmonte2, I. McGill2, D. Hartl2

    1King's College London, London, United Kingdom, 2Quell Therapeutics Ltd, London, United Kingdom

    *Purpose: Life-long pharmacological immunosuppression (IS) is considered essential to prevent rejection following liver transplantation (LT), but is associated with significant side effects such as infections,…
  • 2022 American Transplant Congress

    Pre-Emptive Rituximab to Prevent Post Transplant Lymphoproliferative Disorder (PTLD) in Pediatric Kidney Transplant Recipients with EBV DNAemia: A Case Series from the Pediatric Nephrology Research Consortium (PNRC)

    I. Ashoor1, S. Ranabothu2, S. Al-Akash3, A. Moudgil4, Y. Shi4, S. Kizilbash5, D. Puliyanda6, V. Dharnidharka7

    1LSU Health Sciences Center New Orleans, New Orleans, LA, 2Arkansas Children's Hospital, Little Rock, AR, 3Driscoll Children's Hospital, Corpus Christie, TX, 4Children's National Medical Center, Washington, DC, 5University of Minnesota Medical Center, Minneapolis, MN, 6Cedars-Sinai Medical Center, Los Angeles, CA, 7Washington University in St. Louis, St Louis, MO

    *Purpose: The use of Rituximab (RTX) to prevent PTLD in patients with EBV DNAemia is an established strategy in hematopoietic stem cell transplants, but with…
  • 2022 American Transplant Congress

    Clinical Evolution of Patients with De Novo DSA After Kidney Transplantation

    C. López del Moral1, N. Lachmann2, S. Hergovits2, D. Stauch2, A. Akifova3, M. Naik3, B. Osmanodja3, D. Schmidt3, K. Budde3

    1Nephrology department-IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Institute for Transfusion Medicine, HLA-Laboratory, Charité - Universitätsmedizin, Berlin, Germany, 3Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin, Berlin, Germany

    *Purpose: De novo donor-specific antibodies(dnDSA) are related to antibody-mediated rejection(ABMR), but the evolution of patients after dnDSA is variable and not always ABMR and graft…
  • 2022 American Transplant Congress

    Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)

    D. J. Reich1, A. Schlegel2, M. Rizzari3, D. Foley4, M. DeVera5, W. Chapman6, G. Roll7, A. Saharia8, C. Quintini9, S. Florman10, S. Merani11, S. Mao12, A. Pinna13, M. Akoad14, C. Kubal15, S. Alexopoulos16, H. Bohorquez17

    1Drexel University, Philadelphia, PA, 2Careggi U, Florence, Italy, 3Henry Ford, Detroit, MI, 4U Wisconsin, Madison, WI, 5Loma Linda, Loma Linda, CA, 6Washington U, Saint Louis, MO, 7UCSF, SF, CA, 8Methodist, Houston, TX, 9Cleveland Clinic, Cleveland, OH, 10Mount Sinai, NY, NY, 11U Nebraska, Omaha, NE, 12Mayo, Jacksonville, FL, 13Cleveland Clinic, Weston, FL, 14Lahey, Burlington, MA, 15Indiana U, Indianapolis, IN, 16Vanderbilt, Nashville, TN, 17Ochsner, New Orleans, LA

    *Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…
  • 2022 American Transplant Congress

    Donor-Derived Cell-Free DNA as a Biomarker of T Cell Mediated Rejection in Pediatric Kidney Transplant Patients

    R. Dandamudi1, S. Federman2, R. Woodward2, S. Dholakia2, L. Walther1, V. Dharnidharka1

    1Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, 2CareDx, Brisbane, CA

    *Purpose: T-cell-mediated rejection (TCMR) is a major cause of kidney allograft failure which requires kidney biopsy for a definitive diagnosis. Donor-derived cell-free DNA (dd-cfDNA) is…
  • 2022 American Transplant Congress

    The Renin Angiotensin System (RAS) After Pig-to-Baboon Kidney Transplantation

    C. Hansen-Estruch1, M. H. Bikhet1, M. Javed1, D. Ayares2, A. Katsurada3, R. Satou3, W. Shao3, D. K. Cooper1, L. G. Navar3, E. Judd4

    1Surgery, University of Alabama at Birmingham, Birmingham, AL, 2Revivicor, Blacksburg, VA, 3Department of Physiology and Hypertension and Renal Center, Tulane University, New Orleans, LA, 4Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Relatively long-term survival after life-supporting pig-to-baboon kidney transplantation has been achieved. However, there are documented episodes of hypovolemia during the post-transplant period from an…
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