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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Mortality in Solid Organ Transplant Recipients with a Pretransplant Cancer Diagnosis

    A. Hart1, R. Pfeiffer2, B. Morawski3, C. Lynch4, Y. Zeng5, K. Pawlish6, K. Yu7, D. Hurley8, E. Engels7

    1Hennepin Healthcare, University of Minnesota, Minneapolis, MN, 2Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 3Cancer Registry of Idaho, Boise, ID, 4Epidemiology, University of Iowa, Iowa City, IA, 5North Dakota Statewide Cancer Registry, Grand Forks, ND, 6New Jersey State Cancer Registry, Trenton, NJ, 7Infections and Immunoepidemiology Branch, National Cancer Institute, Bethesda, MD, 8University of South Carolina, Columbia, SC

    *Purpose: Transplant-associated immunosuppression may cause cancer recurrence in patients with a pretransplant cancer, but little is known about outcomes among these recipients.*Methods: We used data…
  • 2022 American Transplant Congress

    Post-Kidney Transplant Valacyclovir or Valganciclovir for EBV Prophylaxis: A Randomized Controlled Trial

    P. S. Verghese1, A. Matas2, S. Chinnakotla2, M. Evans3, H. Balfour Jr4

    1Pediatric Nephrology, Northwestern University, Feinberg School of Medicine, Minneapolis, MN, 2Surgery, University of Minnesota Medical School, Minneapolis, MN, 3Biostatistics, University of Minnesota, Minneapolis, MN, 4Lab Medicine & Pathology, University of Minnesota, Minneapolis, MN

    *Purpose: EBV viremia post-kidney transplant (KTx) has no proven prophylaxis.*Methods: In this randomized, open-label trial [NCT01329185], adult and pediatric recipients were randomly assigned (1:1) to…
  • 2022 American Transplant Congress

    Safety and Efficacy of Peri-Vaccination Antimetabolite Hold to Augment Third SARS-CoV-2 Vaccine Dose Response in Lung Transplant Recipients

    S. Frey, J. Ruck, J. Alejo, L. Barker, W. Werbel, R. Avery, D. Segev, P. Shah

    Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: Lung transplant recipients (LTRs) are less likely than other solid organ transplant recipients (SOTRs) to develop an antibody response to SARS-CoV-2 vaccination. Mycophenolate has…
  • 2022 American Transplant Congress

    Efficacy and Safety of Angiotensin II Compared to Catecholamine Vasopressors as a First-Line Vasopressor for Perioperative Hypotension in Kidney Transplant Recipients

    G. Urias1, J. Benken1, A. Lichvar2, D. Pierce1, L. Andrews1, K. Dalton3, A. Datta1, H. Nishioka1, E. Benedetti1, S. Benken1

    1University of Illinois at Chicago, Chicago, IL, 2University of California San Diego Health, San Diego, CA, 3St. David's Healthcare, Austin, TX

    *Purpose: Perioperative use of catecholamine vasopressors (CV) in kidney transplantation (KT) have been associated with negative renal outcomes and the development of arrhythmias. A more…
  • 2022 American Transplant Congress

    Individual and Community-Level Social Determinants of Health in Liver Transplant

    M. Yilma1, R. Cogan2, N. Mehta3, J. Neuhaus2, J. Voelkel4, C. Light5, I. Allen2, R. Hirose2

    1General Surgery, University of California, San Francisco, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA, 3UCSF, San Francisco, CA, 4Kaiser Permanente Northern California, San Francisco, CA, 5UCSF Medical Center, San Francisco, CA

    *Purpose: To investigate the individual and census-level social determinants of health on liver transplant listing.*Methods: Retrospective review of patients referred to the University of California…
  • 2022 American Transplant Congress

    Pediatric Kidney Transplant Delays Due To Respiratory Viruses: A Provider Survey

    T. A. Heald-Sargent1, S. Manz2, T. Barton3, P. Verghese4

    1Pediatric Infectious Diseases, Lurie Children's Hospital/Northwestern University, Chicago, IL, 2Central Michigan University, Mount Pleasant, MI, 3Pediatric Infectious Diseases, UT Health San Antonoio, San Antonio, TX, 4Pediatric Nephrology, Lurie Children's Hospital/Northwestern University, Chicago, IL

    *Purpose: This study aimed to characterize the management and impact of respiratory viral infections on pediatric kidney transplantation waitlisted candidates.*Methods: An IRB-approved, anonymous REDCap survey…
  • 2022 American Transplant Congress

    Semaglutide Tolerability and Efficacy in Patients with Chronic Kidney Disease Stage 4, 5 and End Stage Renal Disease

    J. J. Long, A. Lemke, V. Sudhindran, N. Pencovici, A. Kukla, T. Diwan

    Mayo Clinic, Rochester, MN

    *Purpose: Obesity is often a barrier to kidney transplantation (KT) due to increased perioperative risks and worse outcomes with many transplant centers setting BMI cut…
  • 2022 American Transplant Congress

    Bcl6 Regulates NFκB-Controlled Endothelial Inflammation and Apoptosis

    A. Franco Acevedo, N. Valenzuela

    Pathology and Laboratory Medicine, UCLA, Los Angeles, CA

    *Purpose: Endothelial cells (EC) centrally regulate leukocyte access to peripheral tissue and immune cell activation, and exhibit remarkable tissue-specific diversity. However, the molecular mechanisms underlying…
  • 2022 American Transplant Congress

    Early Clinical Experience With Alvr109, A Partially Hla-matched Sars-cov-2 Specific T-cell Therapy, In Immunocompromised Patients With Covid-19

    G. Haidar1, J. Jacobs2, K. Hughes2, K. McCormick2, A. Naqvi2, M. Agha2, T. Bogdanovich2, B. Johnson2, J. Kozar2, E. Lendermon2, C. Marino2, A. Raptis2, F. Silveira2, W. Marshall3, M. Miller3, E. Atillasoy3, J. Mellors2

    1University of Pittsburgh, Pittsburgh, PA, 2UPitt, Pittsburgh, PA, 3Allovir, Waltham, MA

    *Purpose: Therapies for COVID-19 in immunocompromised (IC) patients (pts), including transplant (tx) pts, are limited. We describe our experience with ALVR109, an allogeneic, partially HLA-matched…
  • 2022 American Transplant Congress

    The Development of a Scientific Registry of Transplant Recipients Data Query Tool: A Human-Centered Design Process

    C. Schaffhausen1, A. Hart2, C. S. Zinner3, A. K. Israni2, J. Snyder1

    1Hennepin Healthcare Research Institute, Minneapolis, MN, 2Hennepin Healthcare (HHS) / University of Minnesota (UMN), Minneapolis, MN, 3Accenture Federal Services, Washington, DC

    *Purpose: The Scientific Registry of Transplant Recipients (SRTR) provides national transplant data in various forms, including the OPTN/SRTR Annual Data Report (ADR). The ADR includes…
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