Abstracts Archive - Page 12 of 1683 - ATC Abstracts

2022 American Transplant Congress
Eliminating Hepatitis C Positive Status from Kidney Donor Profile Index (KDPI) Calculations Results in Improved Transplant Rates and Outcomes in an Elderly Veteran Population
R. Lopez-Soler¹, A. Thorndyke¹, C. Trotter¹, A. Abadier², M. Samra¹
¹Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, ²Surgery, Loyola University Medical School, Maywood, IL
*Purpose: Overall mortality on the kidney transplant waiting list is higher for older patients. The average age of waitlisted veteran patients is 64, with patients…
2022 American Transplant Congress
Access to Pediatric Kidney Transplant: The Impact of Mental Health Diagnoses and Social Determinants of Health
E. Blanchette¹, E. Benz¹, J. Armendariz¹, K. McKinnon¹, M. Chandran², E. S. Christofferson¹, M. Bisek¹, M. Bock¹
¹Children's Hospital Colorado, Aurora, CO, ²Pharmacy, UNC Hospitals, Chapel Hill, NC
*Purpose: Limited and delayed access to kidney transplant (KT) has been associated with characteristics of adult KT candidates, including mental health (MH) diagnoses, negative social…
2022 American Transplant Congress
Results Of The Ctot19 Trial: Infliximab (IFX) Induction Does Not Impact 2-year Outcomes In Deceased Donor Kidney Transplant Recipients
P. Heeger¹, B. Armstrong², T. Alhamad³, D. Brennan⁴, J. Bromberg⁵, S. Bunnapradist⁶, S. Chandran⁷, R. Fairchild⁸, D. Foley⁹, R. Formica¹⁰, I. W. Gibson¹¹, D. Hricik¹², K. Kesler², R. B. Mannon¹³, M. Menon¹⁰, K. Newell¹⁴, P. Nickerson¹¹, J. Odim¹⁵, E. Poggio⁸, R. Sung¹⁶, R. Shapiro¹, K. Tinckam¹⁷, F. Vincenti⁷
¹Mount Sinai, New York, NY, ²Rho, Durham, NC, ³Washington U, Saint Louis, MO, ⁴Johns Hopkins, Baltimore, MD, ⁵U Maryland, Baltimore, MD, ⁶UCLA, Los Angeles, CA, ⁷UCSF, San Francisco, CA, ⁸Cleveland Clinic, Cleveland, OH, ⁹U Wisconsin, Madison, WI, ¹⁰Yale, New Haven, CT, ¹¹U Manitoba, Winnipeg, MB, Canada, ¹²U Hosp Case, Cleveland, OH, ¹³U Nebraska, Omaha, NE, ¹⁴Emory, Atlanta, GA, ¹⁵NIAID NIH, Rockville, MD, ¹⁶U Michigan, Ann Arbor, MI, ¹⁷U Hlth Network, Toronto, ON, Canada
*Purpose: Ischemia-reperfusion (IR) of a kidney transplant (KTx) up-regulates tumor necrosis factor alpha (TNF) production within the allograft. IR-induced TNF amplifies post-KTx allograft inflammation and…
2022 American Transplant Congress
Gsk3beta Regulates the Resolution of Liver Ischemia Reperfusion Injury via MerTK
H. Zhang¹, M. Ni², J. Zhang¹, R. Busuttil¹, J. Kupiec-Weglinski¹, W. Li³, X. Wang², Y. E. Zhai¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, ³China-Japan Union Hospital of Jilin University, JiLing, China
*Purpose: We have shown previously that glycogen synthase kinase β (Gsk3β) regulates liver inflammatory activation against ischemia/reperfusion injury (IRI). The question of whether it also…
2022 American Transplant Congress
Long-Term Outcomes in Living-Donor Preemptive Kidney Transplants: Results from a Brazilian Single-Center Cohort Study
B. Beraldo, L. R. Requião-Moura, M. Gaspar, R. D. Foresto, H. Tedesco-Silva, J. Medina-Pestana
Nephrology Division - Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil
*Purpose: To evaluate predictors of long-term graft function and unfavorable outcomes in living-donor preemptive kidney transplant recipients.*Methods: A single-center cohort study enrolled 223 living-donor preemptive…
2022 American Transplant Congress
De Novo Focal Segmental Glomerulosclerosis in the Kidney Allograft: Association with Alloimmunity Leading to Poor Outcome
J. Leon¹, J. Duong Van Huyen², A. Abderrahmane¹, D. Anglicheau¹, C. Legendre¹, M. Rabant²
¹KIDNEY TRANSPLANTATION, Necker Hospital, Paris, France, ²KIDNEY PATHOLOGY, Necker Hospital, Paris, France
*Purpose: Focal Segmental Glomerulosclerosis (FSGS) can be found de novo (Dn) or as a recurrence in kidney allograft. While FSGS recurrence has been extensively described…
2022 American Transplant Congress
Leveraging Single-Cell Signatures in Kidney Transplant Biopsies Uncovers Immunological Heterogeneity Within Rejection Phenotypes
J. Callemeyn¹, B. Lamarthée¹, P. Koshy², T. Debyser³, E. Van Loon¹, A. Franken⁴, T. Van Brussel⁴, I. Arijs⁴, D. Lambrechts⁴, M. Rabant⁵, A. Senev¹, T. Vaulet⁶, C. Tinel¹, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²Department of Morphology and Molecular Pathology, University Hospitals Leuven, Leuven, Belgium, ³Faculty of Medicine, KU Leuven, Leuven, Belgium, ⁴Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium, ⁵Necker-Enfants Malades Institute, Institut national de la santé et de la recherche médicale (Inserm), Université de Paris, Paris, France, ⁶ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
*Purpose: Rejection of the kidney allograft is hallmarked by the accumulation of inflammatory cells within the renal architecture, leading to microvascular or tubulointerstitial inflammation. However,…
2022 American Transplant Congress
Evaluation of Donor Exclusion Criteria in Living Donor Liver Transplantation: A Single-Center Experience
D. Daskalaki, M. E. Akoad, J. Kim, C. J. Simon, Y. Cheah
Hepatobiliary Surgery and Liver Transplantation, Lahey Hospital and Medical Center, Burlington, MA
*Purpose: Liver donation is fundamental in increasing the pool of available grafts. Careful evaluation of each donor ensures the best outcomes for the recipient and…
2022 American Transplant Congress
Impact of Donor-to-Recipient Body Surface Area Ratio on Graft Survival and Mortality Following Deceased Donor Liver Transplants
S. Radomski, L. Zeiser, A. Massie, S. Ottmann, D. Segev, E. King
Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: The impact of size mismatch on graft survival in living donor liver transplant is well established but is not a common concern in deceased…
2022 American Transplant Congress
The Development of a Scientific Registry of Transplant Recipients Data Query Tool: A Human-Centered Design Process
C. Schaffhausen¹, A. Hart², C. S. Zinner³, A. K. Israni², J. Snyder¹
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²Hennepin Healthcare (HHS) / University of Minnesota (UMN), Minneapolis, MN, ³Accenture Federal Services, Washington, DC
*Purpose: The Scientific Registry of Transplant Recipients (SRTR) provides national transplant data in various forms, including the OPTN/SRTR Annual Data Report (ADR). The ADR includes…