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  • 2016 American Transplant Congress

    Plasma Alemtuzumab Levels Show Great Interpatient Variability, but Are Not Associated with Late Acute Rejection in Simultaneous Pancreas-Kidney Recipients.

    J. Bank,1 M. Mallat,1 C. Jol-van der Zijde,2 R. Bredius,2 P. van der Boog,1 A. Braat,3 J. Ringers,3 M. Reinders,1 J. de Fijter.1

    1Nephrology, LUMC, Leiden, Netherlands; 2Pediatrics, LUMC, Leiden, Netherlands; 3Surgery, LUMC, Leiden, Netherlands.

    Introduction: Alemtuzumab induction followed by a steroid-free, tacrolimus (Tac) and mycophenolate mofetil (MMF) based regimen effectively prevented acute rejection after simultaneous pancreas-kidney transplantation (SPKT). Acute…
  • 2016 American Transplant Congress

    Outcomes with Steroids Alone for Biopsy-Proven Pancreas Transplant Rejection.

    S. Salahuddin,1 B. Astor,1 S. Parajuli,1 A. Djamali,1 J. Odorico,2 D. Mandelbrot.1

    1Department of Nephrology, University of Wisconsin, Madison, WI; 2Department of Surgery, University of Wisconsin, Madison, WI.

    There is little published data on the response of pancreas rejection to steroids alone. We reviewed 42 pancreas transplant recipients between 01/1997 and 12/2013 at…
  • 2016 American Transplant Congress

    Utilization of Plasmapheresis and High Dose of Immunoglobulins in the Treatment of the High Level of De Novo Donor Specific Antibodies for the Successful Islet Allotransplantation.

    J. Solomina,1 Z. Tekin,1 S. Matosz,1 K. Golab,1 C. Thomas,2 J. Golebiewska,3 S. Ramachandran,1 L. Schenck,1 W. Chon,1 M. Tibudan,1 N. Marek-Trzonkowska,4 J. Millis,1 P. Witkowski.1

    1Surgery, University of Chicago, Chicago, IL; 2Medicine, University of Chicago, Chicago, IL; 3Internal Medicine, Medical University of Gdansk, Gdansk, Poland; 4Family Medicine, Medical University of Gdansk, Gdansk, Poland.

    Background.Development of donor specific antibodies (DSA) after islet transplantation has been a poor prognostic factor for graft survival, while no intervention is implemented. Here, we…
  • 2016 American Transplant Congress

    Graft Versus Host Disease (GVHD) in Patients with Pancreas Transplant Alone (PTA).

    M. Mujtaba,1 A. Sharfuddin,2 A. Khalil,2 T. Taber,2 M. Goble,2 J. Powelson,2 J. Fridell.2

    1Division of Nephrology, University of Texas Medical Branch, Galveston, TX; 2Transplant, Indiana University School of Medicine, Indianapolis, IN.

    GVHD is rare after kidney-pancreas transplant with 18 case reports to date and never been described in the setting of PTA.We share our experience.Patient A:…
  • 2016 American Transplant Congress

    An Analysis of Factors Associated with Pancreas Allograft Thrombosis.

    J. Steggerda, K. Bornhurst, A. Annamalai, A. Peng, J. Mirocha, D. Dafoe.

    Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.

    A successful simultaneous pancreas-kidney (SPK) transplant in recipients with end-stage diabetic nephropathy will provide normoglycemia and exert a salutary effect on neurovascular complications. Early, non-technical…
  • 2016 American Transplant Congress

    Injurious Procoagulant Pathways During Prolonged Cold Storage of the Donor Pancreas.

    B. Sandhu, S. Charitidou, N. Vallant, A. McLean, D. Taube, P. DiCocco, P. Herbert, J. Crane, V. Papalois.

    West London Renal and Transplant Centre, London, United Kingdom.

    Background: Analyses of pancreas transplant outcomes have revealed that pancreatic grafts exhibit an enhanced intolerance to prolonged cold ischaemia time (CIT), however the underlying pathophysiology…
  • 2016 American Transplant Congress

    Mechanical Thrombectomy for the Treatment of Pancreas Transplant Venous Thrombosis: A Single Center Experience.

    S. Shin,1 H. Ko,2 K. Ko,2 Y. Kim,1 J. Choi,1 J. Jung,1 D. Han.1

    1General Surgery, Asan Medical Centere, Seoul, Republic of Korea; 2Radiology, Asan Medical Center, Seoul, Republic of Korea.

    The aim of this study is to investigate the safety and efficacy of mechanical thrombectomy used as a tool for graft rescue in patients with…
  • 2016 American Transplant Congress

    Detection of Venous Thrombi by Microdialysis Catheters and Angiographic Guided Thrombus Extraction in Two Solitary Pancreas Transplants.

    G. Kjosen,1 R. Horneland,2 E. Aandahl,2 O. Oyen,2 T. Tonnessen,1,3 H. Hakon.1

    1Anesthesiology, Oslo University Hospital, Oslo, Norway; 2Transplantation Surgery, Oslo University Hospital, Oslo, Norway; 3Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

    Introduction: The complication rate after pancreas transplantation (PTx) is very high, with venous thrombosis being the most commonly occurring complication that leads to early graft…
  • 2016 American Transplant Congress

    Duodenal Graft Complications After Pancreas Transplant: Evolving Management.

    D. Al-Adra,1 J. Laurence,2 A. Norgate,1 N. Goldaracena,1 M. Marquez,1 A. Barbas,1 M. Dib,1 M. Selzner,1 M. Cattral.1

    1Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, ON, Canada; 2Royal Prince Alfred Institute of Academic Surgery, University of Sydney, Sydney, New South Wales, Australia.

    Introduction Pancreas transplantation is an established treatment for insulin-dependent-diabetes-mellitus with renal failure. However, complications relating to the transplant duodenum remain a significant cause of morbidity…
  • 2016 American Transplant Congress

    What Is the Decline Rate of Pancreata Attributed to Donation After Cardiac Death When the Accompanied Kidney Is Transplanted?

    T. Alhamad,1 K. Lentine,2 A. Taha,2 J. Wellen,1 D. Brennan.1

    1Washington University in St. Louis, St. Louis; 2Saint Louis University, St. Louis.

    Background:Pancreas transplantation in the U.S. has declined steadily in the U.S. over the past decade despite international growth of the practice. Reasons for this decline…
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