2016 American Transplant Congress
HLA Antibody Clonality and Epitopes Dictate Complement Activation.
Background: Alloimmunization results in production of polyclonal donor specific antibodies (DSA) against human leukocyte antigens (HLA), which mediate endothelial cell activation, leukocyte recruitment, and complement…2016 American Transplant Congress
The Role and Mechanism of CD40/CD40L Expression on Different T-Cell Subsets.
Background: Several T-cell costimulatory pathways (i.e. CD28:B7 and CD40:CD40L) play a critical role in modulating alloreactivity, but their function on distinct T cell subsets remains…2016 American Transplant Congress
Prospective Long-Term Analysis of B- and Plasma Cell Subsets in Renal Transplant Patients After Combined Treatment with Rituximab and Bortezomib in Antibody Mediated Rejection.
Nephrology, Charité Berlin, Berlin, Germany.
Treatment of antibody-mediated rejection (AMR) in renal transplant (Tx) patients (pts) is still challenging and long-term outcome remain poor. Our present treatment strategy with bortezomib…2016 American Transplant Congress
Early De Novo DSA with T Cell Mediated Rejection (TCMR) Is Associated with Allograft Dysfunction with Chronic Injury.
De novo anti-donor HLA specific antibody (DSA) detected post-renal transplantation is associated with adverse outcomes. However, the relationship between early de novo DSA and subsequent…2016 American Transplant Congress
Center Volume Is Associated with Outcome Following Pancreas Transplantation within the Eurotransplant Region.
Introduction Outcome following all kinds of surgery depends on several factors, amongst these the annual volume-outcome relationship. This might also be the case in a…2016 American Transplant Congress
Long Term Results on Pancreas Transplant Beyond the Standard Indications, at a Single Center.
Introduction: Simultaneous kidney-pancreas (SKP) transplantation has become the best treatment option for patients with end stage renal disease (ESRD) and type 1 diabetes (T1D). In…2016 American Transplant Congress
Use of Integrated National Registry and Pharmacy Claims Data to Identify Diabetes Mellitus After Live Pancreas Donation.
Living donor pancreas transplant is a potential treatment for diabetic patients with end-organ complications. Early post-donation surgical risks of living pancreas donation have been reported,…2016 American Transplant Congress
Widespread Weight Gain After Pancreas Transplantation May Worsen Metabolic Graft Function.
Department of Surgery, SUNY Upstate Medical University, Syracuse, NY.
Introduction: Outcome after pancreas transplantation (tx) has improved over time and an increasing number of recipients remain insulin independent and enjoy a better quality of…2016 American Transplant Congress
Pancreatic Allograft Failure in Latino Recipients: Diabetes Mellitus Type 2 Conversion?
Baylor University Medical Center, Dallas, TX.
Introduction:Pancreas transplantation is the definitive treatment for diabetes mellitus (DM). The advantages of simultaneous kidney pancreas transplant in Latinos have been demonstrated previously, but there…2016 American Transplant Congress
Impact of Simultaneous Pancreas-Kidney Transplantation versus Kidney Transplant Alone on Patient and Graft Survival in Type 2 Diabetics with Elevated BMI.
Background: Simultaneous Pancreas-Kidney transplantation (SPKT) is becoming increasingly common in patients with Type 2 diabetes (T2DM). The BMI threshold for listing for SPKT in this…
American Transplant Congress abstracts