2016 American Transplant Congress
In Vitro Induction of T Regulatory Cells by Multipotent Adult Progenitor Cells.
Regenerative Medicine, Athersys, Inc, Cleveland, OH.
There is increasing evidence that transplanted adult stemcells remain undifferentiated and often are cleared after a short time.However, these short-lived stem cells still promote recovery…2016 American Transplant Congress
CoCl2 Induced ER Stress Protein Mediated Cytotoxicity in FK506 Treated Hepatoma HepG2 Cells.
Background; The effects of FK506 on the endoplasmic reticulum (ER) mediated stress pathway accelerates CoCl2 - induced cytotoxicity in human hepatoma HepG2 cell line were…2016 American Transplant Congress
Calcineurin Inhibitors Promote Metastasis in Post-Transplant Colorectal Cancer Through Cancer Related- Exosomes Released from Cancer Cells in TGF Beta Independent Epitheilal to Mesenquimal Transition.
Introduction: Cancer is one of the major causes of death in kidney transplantation. Despite more mortality in colon cancer (CRC), similar incidence than general population…2016 American Transplant Congress
Bortezomib Impacts Tenascin mRNA in PBMNCs.
Medical University of South Carolina, Charleston.
Tenascin (TNC) is a gene thought to play a role in the binding of receptors and syndecan binding. Syndecans are signal transmembrane proteins that act…2016 American Transplant Congress
Effect of Isolated Intraperitoneal Sirolimus Treatment on the Kidneys of C57BL/6 Mice.
Sirolimus, a mammalian target of rapamycin inhibitor, is widely used in transplantation. However, the mechanism by which sirolimus induces adverse effects such as proteinuria and…2016 American Transplant Congress
Mechanism of FK506 Induced TNF Related Apoptosis in Jurkat T Cells.
Department of Surgery, Chonnam National University Hospital, Gwangju, Korea.
Purpose: To elucidate the mechanism of FK506 induced TRAIL(TNF related apoptosis inducing ligand) –R1(DR4) and TRAIL-R2(DR5) in FK506-treated Jurkat T cells. And signal transduction pathway…2016 American Transplant Congress
Kidney Allotransplantation Induces the Differentiation of Antigen-Experienced CD8 T Cells with Enhanced Metabolic Profiles.
Background. Naïve and memory CD8 T cells have been shown to exhibit different metabolic profiles, especially upon antigen stimulation. However, it is unknown whether the…2016 American Transplant Congress
Eliminating Xenoantigen Expression on Swine Red Blood Cells.
Background:The rapidly improving tools of genetic engineering may make it possible to overcome humoral immune barrier that prevents xenotransplantation. We hypothesize that levels of human…2016 American Transplant Congress
Indirect Allo-Antigen Stimulation Identifies the Presence of Either Regulatory IL-10 or of Effector Cytokines IFN-g, IL-21, IL-17a Production by Human Blood Allo-Reactive Memory TFH and TCONV CD4+ T Cells.
Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA.
Background: It is well accepted that human CD4+ T cell allo-immunity plays pivotal roles during cellular and humoral allograft rejection. While our previous analysis showed…2016 American Transplant Congress
Adiponectin Is Produced by Leukocytes Infiltrating Renal Transplants.
Immunology, Cleveland Clinic, Cleveland, OH.
Fat is now recognized as a source of immunologically significant cytokines. Adiponectin, the most abundant adipokine, is usually classified as an anti-inflammatory cytokine because decreased…
American Transplant Congress abstracts