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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    The Role Of Ferroptosis In Modulating Ischemia Reperfusion Injury(IRI) Gene Expression In Marginal Donor Livers(MDLS) Using The Novel Protect Normothermic Perfusion Pump

    M. D. Nazzal1, K. Kurashima2, J. Bettag2, A. Chen2, S. Bruno2, A. Nagarapu2, J. Van Nispen1, J. Krebs2, J. Teckman2, D. Carpenter3, D. Hermelin3, C. Varma1, A. Jain2

    1Surgery, Saint Louis University, Saint Louis, MO, 2Pediatrics, Saint Louis University, Saint Louis, MO, 3Pathology, Saint Louis University, Saint Louis, MO

    *Purpose: Severe IRI can impair liver allograft when using MDLs and accounts for high discard rates. We tested iron chelators to reduce ferroptosis and IRI.…
  • 2022 American Transplant Congress

    Cardiovascular Assessment After Kidney Transplantation in Children and Adolescents

    J. Liu, L. Zhang, X. Li, L. Zhu, Y. Lin, X. He, L. Liu, J. Li, C. Wang, S. Li

    The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    *Purpose: End-stage renal disease is often accompanied by cardiovascular events, and cardiovascular events still exist after kidney transplantation. Cardiovascular disease is the main cause of…
  • 2022 American Transplant Congress

    Degree of Pre-Liver Transplant Immune Dysfunction Correlates with Post-Transplant Cancer Recurrence

    G. S. Prakash1, G. G. Panayotova1, S. Simonishvili1, Y. Qin1, L. Jin1, T. Ayorinde1, L. J. Minze2, F. Paterno1, L. Brown1, A. Amin1, D. Liu1, R. Ghobrial2, J. V. Guarrera1, K. E. Lunsford1

    1Rutgers New Jersey Medical School, Newark, NJ, 2Houston Methodist Hospital, Houston, TX

    *Purpose: Despite stringent selection criteria for liver transplant (LT) in patients with liver-limited malignancy, post-transplant cancer recurrence remains problematic. We have previously identified a pre-LT…
  • 2022 American Transplant Congress

    Longevity Matching for Living Donor Renal Transplantation

    S. Karhadkar1, J. Dawes1, K. Wirshup1, J. Kolansky1, A. Gregor1, A. Diamond2, A. DiCarlo1

    1Temple University Hospital, Philadelphia, PA, 2-, Garnet Valley, PA

    *Purpose: Living donor kidney transplantation (LDKT) continues to become a more prevalent treatment method for ESRD and is known to increase both organ availability and…
  • 2022 American Transplant Congress

    Avoiding Cytomegalovirus Mismatching in Deceased Donor Kidney Allocation System in the US

    B. Tanriover1, B. Sandikci2, Y. Ulukus3, M. A. Ergun2, V. K. Ariyamuthu1, M. Al-Obaidi4, T. Zangeneh4

    1Division of Nephrology, The University of Arizona, Tucson, AZ, 2Department of Industrial Engineering, Istanbul Technical University, Istanbul, Turkey, 3Department of industrial Engineering, Istanbul Technical University, Istanbul, Turkey, 4Division of Infectious Disease, The University of Arizona, Tucson, AZ

    *Purpose: Cytomegalovirus (CMV) mismatch, donor-positive/recipient-negative serostatus (D+/R-), carries a high risk of developing CMV infection, graft failure mortality. The current kidney allocation system (KAS) does…
  • 2022 American Transplant Congress

    Organs from Donors with Positive SARS-CoV-2 NAT+ Testing: A Report from the Ad Hoc Disease Transmission Advisory Committee

    L. Danziger-Isakov1, J. D. Goldman1, A. Wooley1, S. Pouch1, A. Agarwal1, G. Berry1, K. Dunn1, S. Ho1, M. Kittleson1, D. H. Lee1, D. Levine1, C. Marboe1, G. Marklin1, R. Razonable1, S. Taimur1, H. Te1, C. Fox2, C. Jett2, S. Booker2, D. Klassen2, R. LaHoz1

    1OPTN, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: Decision to transplant organs from SARS-CoV-2 NAT+ donors(N+D) balances risk of donor-derived infection with the scarcity of available organs to meet the needs of…
  • 2022 American Transplant Congress

    Donor Terminal Creatinine – Does It Matter?

    V. G. Menon, Y. Wert, W. Hoffman, D. Ladie, M. Singh, M. Waybill, H. Yang

    UPMC, Harrisburg, PA

    *Purpose: When assessing deceased donor kidneys, the transplantation team studies several donor variables including creatinine. A creatinine that is elevated immediately prior to procurement can…
  • 2022 American Transplant Congress

    BiomarkeR Initiative to Advance Transplantation OutcomEs in Children (BRITE-c) Analysis

    M. E. Seifert1, L. Sheward2, A. Kho2, N. Rodig2, V. Dharnidharka3, M. Diehl2, R. B. Mannon4, O. Bestard5, T. Blydt-Hansen6, D. M. Briscoe2

    1University of Alabama, Birmingham, AL, 2Boston Children's Hospital, Boston, MA, 3St Louis Children's Hospital, St Louis, MO, 4University of Nebraska, Omaha, NE, 5Bellvitge University Hospital, Barcelona, Spain, 6BC Childrens, Vancouver, BC, Canada

    *Purpose: Recent studies indicate that 25-36% of clinically stable pediatric renal transplant recipients will have subclinical rejection detected on surveillance biopsy. These findings highlight a…
  • 2022 American Transplant Congress

    ESRD is Increasing Faster After Living Kidney Donation Than it Does in the Unselected US Population: A New Risk Metric?

    R. W. Steiner

    UCSD School of Medicine, San Diego, San Diego, CA

    *Purpose: ESRD rates increase exponentially both after kidney donation and as the US population ages. Increases in ESRD rates from the first to the second…
  • 2022 American Transplant Congress

    Early Outcomes Since Implementation of New Kidney Allocation System

    K. Shah, F. Siddiqui, P. N. Chotai, A. Logan, A. Schenk, K. Washburn, A. Limkemann

    Comprehensive Transplant Center, The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: The new Kidney allocation system (nKAS) implemented for optimization of organ placement. Like other organ allocation systems, kidney has been redefined from donation service…
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