Abstracts Archive - Page 117 of 1683 - ATC Abstracts

2022 American Transplant Congress
Serological Response To Three, Four And Five Doses Of Sars-cov-2 Vaccine In Kidney Transplant Recipients
S. Ronicke¹, B. Osmanodja¹, K. Budde¹, A. Jens¹, C. Hammett¹, K. Nadine¹, J. Waiser¹, B. Zukunft¹, F. Bachmann¹, M. Choi¹, W. Ulrike¹, B. Eberspächer², J. Hofmann², F. Grunow¹, M. Mikhailov¹, L. Liefeldt¹, K. Eckardt¹, F. Halleck¹, E. Schrezenmeier¹
¹Department of Nephrology and Medical Intensive Care, Charité – Universitätsmedizin Berlin, Berlin, Germany, ²Labor Berlin - Charité Vivantes GmbH, Berlin, Germany
*Purpose: Mortality from COVID-19 among kidney transplant recipients (KTR) is unacceptably high, and their response to up to three vaccinations against SARS-CoV-2 is strongly impaired.…
2022 American Transplant Congress
Dual Therapy with Esculin and Erythropoietin Attenuates Renal Ischemia-Reperfusion Injury via P2x7 Receptor and Nlrp3 Inflammasome Inhibition, and Pi3k/akt Activation
E. Hafiz¹, W. H. El-Maadawy², M. Hassan³, M. H. Badawy⁴, S. Eldahshan⁴, A. AbuSeada⁵
¹Clinical Research Laboratory Department, Theodor Bilharz Research Institute, Giza, Egypt, ²Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt, ³Immunology Department, Theodor Bilharz Research Institute, Giza, Egypt, ⁴Urology Department, Theodor Bilharz Research Institute, Giza, Egypt, ⁵Anesthesia Department, Theodor Bilharz Research Institute, Giza, Egypt
*Purpose: Renal ischemia/reperfusion (RI/R) is an inevitable condition during renal transplantation with critical clinical outcomes. Accordingly, effective therapies are crucially required.*Methods: In this study, the…
2022 American Transplant Congress
The Role Of Ferroptosis In Modulating Ischemia Reperfusion Injury(IRI) Gene Expression In Marginal Donor Livers(MDLS) Using The Novel Protect Normothermic Perfusion Pump
M. D. Nazzal¹, K. Kurashima², J. Bettag², A. Chen², S. Bruno², A. Nagarapu², J. Van Nispen¹, J. Krebs², J. Teckman², D. Carpenter³, D. Hermelin³, C. Varma¹, A. Jain²
¹Surgery, Saint Louis University, Saint Louis, MO, ²Pediatrics, Saint Louis University, Saint Louis, MO, ³Pathology, Saint Louis University, Saint Louis, MO
*Purpose: Severe IRI can impair liver allograft when using MDLs and accounts for high discard rates. We tested iron chelators to reduce ferroptosis and IRI.…
2022 American Transplant Congress
Lung Transplantation For COVID Acute Respiratory Distress Syndrome: A Pediatric And Adult Case Series
C. Arendale¹, D. Kumar², P. S. Garcha³, C. Kutac⁴, G. Loor¹, A. Rana¹, J. Goss¹, N. Galvan¹
¹Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, ²Department of Biochemistry, Baylor College of Medicine, Houston, TX, ³Department of Medicine, Baylor College of Medicine, Houston, TX, ⁴Baylor St. Luke’s Medical Center, Houston, TX
*Purpose: Lung transplantation (LTx) has been shown to be a viable treatment for irreversible lung disease caused by COVID-19. Given the limited data on the…
2022 American Transplant Congress
Incidence of Delayed Graft Function in Kidneys Recovered After Normothermic Regional Perfusion
L. James¹, M. D'Angelo¹, J. Carillo¹, J. C. Berger¹, D. E. Smith¹, N. Moazami¹, B. Lonze²
¹NYU Langone Health, New York, NY, ²NYU Langone Transplant Institute, New York, NY
*Purpose: The use of normothermic reperfusion (NRP) following donation after circulatory death (DCD) is an emerging strategy for organ procurement. NRP technique reestablishes circulatory blood…
2022 American Transplant Congress
The Impact Of Monoclonal Antibody Against Sars-CoV2 And Vaccination On Outcomes In Kidney Transplant Recipients With Covid-19
N. M. Ali, V. Tatapudi, R. Chand, k. Sureau, S. Mehta, R. Montgomery
NYU Langone Transplant Institute, New York, NY
*Purpose: Solid organ transplant recipients are at high risk of morbidity and mortality from coronavirus disease 2019 (COVID-19) with mortality rates as high as 30%…
2022 American Transplant Congress
Covid-19 Vaccination Response In Tacrolimus Treated Kidney Transplant Recipients With And Without Mycophenolate Mofetil: Follow-up Of A Randomized Controlled Trial
Z. Al Fatly¹, M. G. Betjes¹, A. L. Messchendorp², J. S. Sanders², M. E. Reinders¹, M. M. Kho¹, A. E. de Weerd¹
¹Department of Internal Medicine, Erasmus MC Transplant Institute University Medical Center, Rotterdam, Netherlands, ²Department of Internal Medicine, Groningen Medical Center, Groningen, Netherlands
*Purpose: To investigate the effect of mycophenolate mofetil (MMF) on SARS-CoV-2 vaccination response in kidney transplant recipients using the standard immunosuppressive regimen of tacrolimus (TAC)…
2022 American Transplant Congress
Case Times For Brain Dead Donors: Longer Is Not Better, No Impact Of Longer Case Time On Organ Yield Or OPO Performance Tier
M. J. Moritz¹, R. Hasz¹, H. Nathan¹, E. Hunt², S. Noreen³, A. Toll⁴
¹Gift of Life Donor Program, Philadelphia, PA, ²Surgery, Lehigh Valley Health Network, Allentown, PA, ³United Network for Organ Sharing, Richmond, VA, ⁴Research, United Network for Organ Sharing, Silverdale, WA
*Purpose: Having observed the steady increase in case times, we wished to examine if this has impacted organ yield*Methods: We conducted a retrospective cohort study…
2022 American Transplant Congress
Donor Terminal Creatinine – Does It Matter?
V. G. Menon, Y. Wert, W. Hoffman, D. Ladie, M. Singh, M. Waybill, H. Yang
UPMC, Harrisburg, PA
*Purpose: When assessing deceased donor kidneys, the transplantation team studies several donor variables including creatinine. A creatinine that is elevated immediately prior to procurement can…
2022 American Transplant Congress
Early Post-Operative Thrombotic Microangiopathy in Deceased Donor Kidney Transplant: A Retrospective Case Series
R. Seneriz¹, A. Mattiazzi¹, G. Guerra¹, T. Harrington², M. Velasquez³
¹Miami Transplant Institute, Miami, FL, ²University of Miami, Miami, FL, ³Jackson Memorial Hospital, Miami, FL
*Purpose: Transplant associated thrombotic microangiopathy (TA-TMA) is characterized by endothelial injury along with thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and kidney graft dysfunction. It can be…