Abstracts Archive - Page 115 of 1683 - ATC Abstracts

2022 American Transplant Congress
The Impact of Frailty Syndrome on Humoral Response to SARS-CoV-2 mRNA Vaccines in Older Kidney Transplant Recipients
M. Schmalz¹, H. Vankova², S. Rajnochova-Bloudickova¹, P. Hruba³, M. Fialova⁴, J. Gurka⁵, M. Magicova¹, I. Striz⁴, I. Zahradka¹, O. Viklicky¹
¹Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ²The Third Faculty of Medicine, Charles University, Prague, Czech Republic, ³Transplantation Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁴Department of Immunology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁵Department of Information Technology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Advanced age is associated with impaired humoral immune response to SARS-CoV-2 mRNA vaccines in kidney transplant recipients (KTR), however mechanisms are poorly understood. Frailty…
2022 American Transplant Congress
Dual Therapy with Esculin and Erythropoietin Attenuates Renal Ischemia-Reperfusion Injury via P2x7 Receptor and Nlrp3 Inflammasome Inhibition, and Pi3k/akt Activation
E. Hafiz¹, W. H. El-Maadawy², M. Hassan³, M. H. Badawy⁴, S. Eldahshan⁴, A. AbuSeada⁵
¹Clinical Research Laboratory Department, Theodor Bilharz Research Institute, Giza, Egypt, ²Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt, ³Immunology Department, Theodor Bilharz Research Institute, Giza, Egypt, ⁴Urology Department, Theodor Bilharz Research Institute, Giza, Egypt, ⁵Anesthesia Department, Theodor Bilharz Research Institute, Giza, Egypt
*Purpose: Renal ischemia/reperfusion (RI/R) is an inevitable condition during renal transplantation with critical clinical outcomes. Accordingly, effective therapies are crucially required.*Methods: In this study, the…
2022 American Transplant Congress
The Impact of Donor Nephrectomy on the Living Donors Aged 75 Years and Older
T. Hiramitsu, T. Tomosugi, K. Futamura, M. Okada, N. Goto, T. Ichimori, S. Narumi, Y. Watarai
Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan
*Purpose: Due to the profound organ shortage, number of living donor kidney transplantation (LDKT) from elder living donor (LD) is increasing. However, there has been…
2022 American Transplant Congress
Sensitization and BK Viremia; Risk Following Sub-Clinical COVID-19 Infection in Pediatric Kidney Transplant Recipients
E. Benz¹, M. Chandran², J. Chuita¹, K. McKinnon¹, A. Sikora¹, M. Bock¹, E. Blanchette¹
¹Children's Hospital Colorado, Aurora, CO, ²University of North Carolina, Chapel Hill, NC
*Purpose: In contrast to high morbidity and mortality of COVID-19 infection (COVIDi) in adult kidney transplant (KT) recipients, these sequelae appear to be muted in…
2022 American Transplant Congress
Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients: Practice Patterns, Report from the Paramour “Pediatric Renal AMR Outcomes” Study
N. Hayde¹, K. Twombley², I. Ashoor³, R. Engen⁴, L. Harshman⁵, R. Zahr⁶, C. Peterson⁷, S. McEwen⁸, A. Jain⁹, R. Garro¹⁰, M. Kallash¹¹, A. Mansuri¹², D. Puliyanda¹³
¹Montefiore Medical Center, Bronx, NY, ²Medical University of South Carolina, Charleston, SC, ³LCMCHealth, New Orleans, LA, ⁴Pediatrics, University of Wisconsin Madison, Madison, WI, ⁵University of Iowa Children's Hospital, Iowa City, IA, ⁶Le Bonheur Children's Hospital, Nashville, TN, ⁷University of Utah, Salt Lake City, UT, ⁸University of Minnesota, Minneapolis, MN, ⁹Wayne State, Troy, MI, ¹⁰Emory Universtiy, Atlanta, GA, ¹¹The Ohio State, Columbus, OH, ¹²Augusta University Medical Center, Augusta, GA, ¹³Cedars-Sinai Med Ctr, West Hollywood, CA
*Purpose: There is insufficient data on children with AMR in the literature, and the optimal therapy for AMR is not well defined. We aim to…
2022 American Transplant Congress
Early Outcomes of Kidney Transplant Recipients from Donors with Severe Sars-cov-2 Pneumonia
M. Rosenzweig, M. Finotti, A. Gupta, S. Lee, N. Onaca, G. J. McKenna, J. Bayer, H. Fernandez, R. Ruiz, E. Martinez, A. Yango, T. Sam, C. Spak, B. Fischbach, G. Testa, A. Wall
Baylor University Medical Center, Dallas, TX
*Purpose: Transplantation of kidneys from donors with active SARS-CoV-2 infection is uncommon due to concerns about the risk of viral transmission and kidney quality. To…
2022 American Transplant Congress
Type 1 Natural Killer T-cells: Key Mediators of Ischemia- Reperfusion Injury in Hepatic Steatosis
J. R. Liggett¹, J. Kang¹, K. Loh¹, K. Oza¹, Y. Cui¹, D. Kwon², H. Li³, B. Kallakury², T. Fishbein¹, W. Cui¹, K. Khalid¹, A. H. Kroemer¹
¹MedStar Georgetown Transplant Institute, Washington, DC, ²Pathology, MedStar Georgetown University Hospital, Washington, DC, ³Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC
*Purpose: Hepatic ischemia-reperfusion injury (IRI) poses a significant risk in liver transplantation and hepatic resection and is further exacerbated by hepatic steatosis. Type 1 Natural…
2022 American Transplant Congress
Donor Exercise Preconditioning Protects Murine Orthotopic Liver Grafts During Ischemia Reperfusion Injury
H. O. Yazdani, C. Kaltenmeier, R. Nakano, R. L. Simmons, D. A. Geller, S. Tohme
Surgery, University of Pittsburgh Medical Center, Pissburgh, PA
*Purpose: Orthotopic liver transplantation (LTx) serves as the gold standard of care in patients with end-stage liver disease. However, a major obstacle to the immediate…
2022 American Transplant Congress
Selective Vascular Decellularization and Endothelial Cells Replacement as a Strategy to Reduce Reperfusion Injury in Bioartificial Organs
G. Haeublein¹, G. Lombardi¹, F. Caro¹, R. Carla¹, D. Guerrieri¹, C. Incardona², D. Casadei³, E. Chuluyan¹
¹CEFYBO, Buenos Aires, Argentina, ²GADOR S.A., Buenos Aires, Argentina, ³Fundación Argentina de Trasplante, Tercer Milenio, Buenos Aires, Argentina
*Purpose: The number of kidney transplants performed each year cannot meet the increasing demand of these organs. Several strategies aim to increasing the offer of…
2022 American Transplant Congress
Early Post-Operative Thrombotic Microangiopathy in Deceased Donor Kidney Transplant: A Retrospective Case Series
R. Seneriz¹, A. Mattiazzi¹, G. Guerra¹, T. Harrington², M. Velasquez³
¹Miami Transplant Institute, Miami, FL, ²University of Miami, Miami, FL, ³Jackson Memorial Hospital, Miami, FL
*Purpose: Transplant associated thrombotic microangiopathy (TA-TMA) is characterized by endothelial injury along with thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and kidney graft dysfunction. It can be…