Abstracts Archive - Page 1138 of 1683 - ATC Abstracts

2017 American Transplant Congress
The IL6/Th17 Pathway May Play Different Roles in Cell-Mediated and Antibody-Mediated Alloimmune Injury in Renal Allografts.
D. Dobi,¹ Q. Tang,² S. Chandran,³ F. Vincenti,³ Z. Laszik.¹
¹Department of Pathology, University of California, San Francisco, San Francisco, CA; ²Department of Surgery, Division of Transplant Surgery, University of California, San Francisco, San Francisco, CA; ³Department of Medicine, Division of Nephrology, University of California, San Francisco, San Francisco, CA
Purpose. IL6 has been shown to contribute to shifting the balance between tolerogenic regulatory T cells and proinflammatory Th17 cells towards the latter. Our study…
2017 American Transplant Congress
Pre-Transplant Panel Reactive T Cells (PRT) with IL-15 as a Risk-Stratifier of Acute Rejection in Kidney Transplant Patients on Belatacept Therapy.
P. Cravedi,¹ I. Gandolfini,¹ C. Donadei,¹ R. Fairchild,² K. Newell,³ R. Mannon,⁴ P. Heeger,¹ CTOT16 Consortium.
¹Dept of Medicine, Icahn School of Medicine at Mount Sinai, New York; ²Dept of Immunology, Cleveland Clinic, Cleveland; ³Dept of Surgery, Emory University, Atlanta; ⁴Renal Division, UAB, Birmingham
While kidney transplant recipients treated with bela without calcineurin inhibitors (CNI) have better 5-10y eGFR versus those on CNI, Belatacept (bela) use is associated with…
2017 American Transplant Congress
Prediction of Renal Allograft Acute Rejection Using a Novel Non-Invasive Model Based on Acoustic Radiation Force Impulse.
C. Yang,¹ Y. Jin,² S. Wu,³ T. Zhu,¹ W. He.²
¹Urology, Zhongshan Hospital, Fudan University, Shanghai, China; ²Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China; ³Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China
Point shear wave elastography (p-SWE) based on acoustic radiation force impulse (ARFI) is a novel technology to quantify tissue stiffness by measuring shear wave speed…
2017 American Transplant Congress
The Effect of Histological Isolated Endarteritis and Solid Endoarteritis Combined with CD20 Positive B Cell Infiltration Appeared in Acute Cellular Rejection on Kidney Allograft Survival.
R. Wang, Y. Jiang, J. Wu, W. Peng, H. Huang, J. Chen.
Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hanghzou, Zhejiang, China
BackgroundEndarteritis post renal transplantation is regarded as T-cell mediated acute rejection by Banff classification. Recently, results from DNA microarrays suggested that endovasculitis did not represent…
2017 American Transplant Congress
Persistence/Progression of Early Banff Borderline Changes (BBC) Is Associated with Chronic Renal Allograft Damage and Can Be Predicted by B Cell Cytokine Profile.
A. Cherukuri, A. Sharma, R. Mehta, S. Hariharan, D. Rothstein.
UPMC, Pittsburgh
The clinical significance of early histological BBC in kidney transplant recipients (KTR) is unclear. It is also unknown if biomarkers predict progression to acute rejection…
2017 American Transplant Congress
The Impact of Early Clinical and Subclinical T Cell Rejection After Kidney Transplantation.
W. Hoffman, P. Sood, R. Mehta, A. Cherukuri, C. Wu, C. Puttarajappa, N. Shah, P. Randhawa, A. Tevar, S. Hariharan.
Medicine and Surgery, University of Pittsburgh, Pittsburgh, PA
Purpose: To evaluate the impact of early Clinical(C-TCMR) and Sub-Clinical(SC-TCMR) T Cell Mediated Rejection on short-term allograft histology and function.Methods: We examined adult kidney alone…
2017 American Transplant Congress
Clinic-Based Medication Education Pilot Program.
N. Sulejmani,¹ H. Albanna,¹ T. Rendulic,² B. Summers,¹ A. Jantz.¹
¹Henry Ford Hospital, Detroit, MI; ²University of Kentucky, Lexington, KY
Purpose: Adherence to medications is crucial for transplant patients as missing medications can result in increased risk of rejection and graft loss. Augmented education may…
2017 American Transplant Congress
Lipid Abnormalities and Cardiovascular Events After Early Conversion to Everolimus in Kidney Transplant Recipients with Pretransplant Diabetes: 24-Month Analysis from Elevate Study.
M. van der Giet,¹ J. de Fijter,¹ F. Oppenheimer,¹ G. Russ,¹ P. Lopez,² G. Bader,² J. Cruzado,¹ H. Holdaas.¹
¹ELEVATE Study Group, Berlin, Germany; ²Novartis Pharma AG, Basel, Switzerland
PURPOSE: Pretransplant (preTx) diabetes is an independent risk factor for cardiovascular (CV) events, and posttransplant (post-Tx) hyperlipidemia further increases CV risk. To analyze the influence…
2017 American Transplant Congress
Post-Transplant Graft Function Is Associated with Major Cardiovascular Events in Kidney Transplant Recipients: A Multicenter Cohort Study.
J. Park,¹ Y. Kim,² S. Yang,³ S. Park,² S.-K. Park,⁴ D. Han,⁵ Y. Kim,² Y. Kim,⁵ J. Lee.⁶
¹Department of Internal Medicine, Dongguk University Ilsan Hospital, Gyeonggi-do, Korea; ²Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ³Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea; ⁴Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁵Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁶Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea
Background: Reduced kidney function is an independent risk factor for cardiovascular disease in the general population. However, the association between post-transplantation graft function and subsequent…
2017 American Transplant Congress
Myocardial Improvement Six Months After Kidney Transplantation: Non-Contrast Cardiac Resonance Study.
M. Contti, L. Morales-Buenrostro, H. Nga, P. Garcia, M. Barbosa, H. Takase, M. da Silva, A. Moyses.
Internal Medicine, Botucatu School of Medicine, Botucatu, Sao Paulo, Brazil
INTRODUCTION: Patients with stage 5 chronic kidney disease (CKD) are at increased risk of cardiovascular disease, considering left ventricular hypertrophy (LVH) an independent risk for…