ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    10 Years of DTAC Experience with Kaposi's Sarcoma – Not Just Another PTLD!

    M. Nalesnik,1 M. Clark,2 S. Tlusty,2 M. Michaels,1 C. Wolfe.1

    1DTAC, Richmond; 2United Network for Organ Sharing, Richmond

    Background:Kaposi's Sarcoma (KS), a tumor derived from the oncogenic virus human herpesvirus-8 (HHV8) is strongly associated with immunodeficiencies. Classically seen with AIDS, it can also…
  • 2017 American Transplant Congress

    In Depth Characterization of the Innate Immune Response in Transplant Recipients with EBV Viremia.

    V. Ferreira, J. Batist, D. Kumar, S. Husain, A. Humar.

    UHN, Toronto, Canada

    Background:Infection with Epstein-Barr virus (EBV) manifests as a spectrum of disease ranging from asymptomatic viremia to PTLD. Innate immune cells such as monocytes/macrophages, dendritic cells…
  • 2017 American Transplant Congress

    The Effiency and Safety of Chemotherapy for Urothelial Carcinoma in Post-Kidney Transplanted Patients.

    Y. Zhu, J. Lin.

    Urology, Capital Medical University Beijing Friendship Hospital, Beijing, China

    Objective: According to our published data, upper tract urothelial carcinoma (UTUC) is the predominant malignancy among Chinese renal transplanted patients. This is quite different from…
  • 2017 American Transplant Congress

    Long-Term Malignancy Risk in Kidney Transplant Recipients Treated with Cyclophosphamide Pre-Transplant for Native Glomerular Disease.

    J. Mills,1 M. Jorgenson,1 J. Fose,1 B. Astor,2 S. Panzer.2

    1Pharmacy, UW Health, Madison, WI; 2Nephrology, UW Health, Madison, WI

    Purpose: To evaluate the incidence of malignancy in kidney transplant recipients who previously received cyclophosphamide for treatment of native glomerular disease.Methods: Single center study of…
  • 2017 American Transplant Congress

    Lymphoproliferative Disorders After Renal Transplantation Along Two Decades: A Large Longitudinal Study.

    A. Franco,1 D. Hernandez,2 N. Maruri,3 A. Alonso,4 M. Crespo,5 A. Mazuecos,6 C. Diaz-Corte,7 M. Gentil.8

    1Nephrology, Hospital General, Alicante, Spain; 2Nephrology, Hospital Carlos Haya, Málaga, Spain; 3Nephrology, Hospital Cruces, Bilbao, Spain; 4Nephrology, Hospital Universitario, A Coruña, Spain; 5Nephrology, Hospital del Mar, Barcelona, Spain; 6Nephrology, Hospital Puerta del Mar, Cadiz, Spain; 7Nephrology, Hospital General, Oviedo, Spain; 8Nephrology, Hospital Virgen del Rocío, Sevilla, Spain

    In a longuitudinal study,we evaluated the cumulative incidence of Posttransplant limphoproliferative disorders(PTLD),its relationship with Epstein Barr Virus (EBV),classical risk factors and outcome in 21546 single…
  • 2017 American Transplant Congress

    Significance of Atypical Cytology in the Evaluation of Patients with End Stage Renal Disease for Transplantation.

    J. Law, O. Ali, H. Brar, P. Luke, A. Sener.

    Urology, Western University, London, ON, Canada

    INTRODUCTION AND OBJECTIVES: Renal transplantation is the most optimal method of treating patients with end-stage renal disease (ESRD). As part of their routine malignancy screening,…
  • 2017 American Transplant Congress

    Incidence, Recurrence and Long Term Survival Post Chemotherapy in Renal Transplant Recipients with Post Transplant Lymphoproliferative Disorder: Single Center Study.

    R. Rathore, K. Tomlinson, H. Dukka, D. Farrugia, M. Lambie.

    Department of Renal Medicine, University Hospitals of North Midlands, Stoke-on-Trent, United Kingdom

    Background: Majority of Post transplant lymphoproliferative disorders(PTLD) occur in the first year post solid organ transplant. The risk factors for development of PTLD include degree…
  • 2017 American Transplant Congress

    Chimerism-Related Allotolerance Is Induced by Exosome Acquisition and Reprogramming of Host Dendritic Cells.

    D. Lema,1 W. Bracamonte-Baran,2 E. Jankowska-Gan,1 F. Claas,3 J. van Rood,3 A. Mulder,3 W. Burlingham.1

    1Surgery - Transplant Division, University of Wisconsin-Madison, Madison, WI; 2Pathology, Division of Immunology, Johns Hopkins University, Baltimore, MD; 3Immunohaematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands

    Maternal microchimerism (MMc) has been associated with allo-specific graft tolerance in mice and humans. This tolerance is associated with membrane allo-antigen acquisition (mAAQ), which is…
  • 2017 American Transplant Congress

    Operational Tolerance in Intestinal Transplantation: A Proven Possibility.

    B. Houlihan,1 P. Cha,1,2 C. Cosentino,1,2 J. Kaiser,1,2 A. Shukla,1 J. Hawksworth,1,2 C. Matsumoto,1 T. Fishbein,1 A. Kroemer.1

    1Transplant Department, Medstar Georgetown University Hospital, Washington, DC; 2Surgery, Walter Reed National Military Medical Center, Bethesda, MD

    A The purpose of this study is to immunologically characterize the first operationally tolerant intestinal transplant (ITx) patient known to date.B Flow cytometry and rtPCR…
  • 2017 American Transplant Congress

    A-Antigen (Ag)-Specific Tolerance Following A-Ag Administration to Infant Mice.

    B. Motyka,1 Y. Wang,1 B. Lamarche,1 I. Adam,1 J. Pearcey,1 K. Tao,1 C. Cairo,2 P. Cowan,3 L. West.1

    1Dept Pediatrics, Alberta Transplant Institute, Canadian National Transplant Research Program, University of Alberta, Edmonton, Canada; 2Dept Chemistry, Alberta Glycomics Centre, University of Alberta, Edmonton, Canada; 3Immunology Research Centre, St Vincent's Hospital, University of Melbourne, Melbourne, Australia

    Purpose: In contrast to adults, ABO-incompatible heart transplantation (ABOi HTx) can safely be performed in infants due to absent/low levels of anti-A/B antibodies (Ab). Tolerance…
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