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American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Simultaneous Pancreas and Kidney Transplant (SPK) – The New Standard of Care for Uremic Patients with Type 2 Diabetes Mellitus (T2DM).

    A. Gruessner, M. Laftavi, V. Whittaker, Z. Acun, O. Pankowycz, R. Gruessner.

    Surgery, SUNY Upstate Medical University, Syracuse, NY

    Introduction: While a SPK is now considered standard of care for uremic T1 DM patients, it is not for T2DM (despite similar medical issues). The…
  • 2017 American Transplant Congress

    Simultaneous Pancreas-Kidney Transplantation and Center Volume: Bigger Is Not Necessarily Better.

    T. Alhamad,1 A. Malone,1 D. Brennan,1 R. Stratta,3 J. Wellen,1 K. Lentine.2

    1Washington University in St. Louis, St. Louis; 2Saint Louis University, St. Louis; 3Wake Forest University, Winston-Salem

    Successful simultaneous pancreas-kidney (SPK) transplantation requires surgical expertise and multidisciplinary medical management. The impact of transplant center volume on pancreas allograft survival after SPK is…
  • 2017 American Transplant Congress

    Utility of Concomitant Biopsy in Simultaneous Pancreas Kidney Transplant Recipients in the Identification of Rejection of Pancreas and Kidney.

    C. Johnson, K. Johnson, B. Kaplan, M. Temkit, R. Heilman, S. Sukumaran Nair, H. Khamash, J. Huskey, G. Mour, H. Chakkera.

    Mayo Clinic Arizona, Phoenix, AZ

    Background: In simultaneous pancreas and kidney transplant (SPKTx) recipients, animal studies suggest concordant rejection rates of 88% (ref: Gruessner et al,1994). Limited information is available…
  • 2017 American Transplant Congress

    Beta Cell-Specific Free Circulating DNA May Predict the Outcome After Clinical Islet Transplantation.

    B. Gala-Lopez,1 D. Neiman,2 T. Kin,1 D. O'Gorman,1 A. Pepper,1 A. Malcolm,1 B. Glaser,3 R. Shemer,2 Y. Dor,2 J. Shapiro.1

    1Department of Surgery, Clinical Islet Transplant Program, University of Alberta, Edmonton, AB, Canada; 2Department of Developmental Biology and Cancer Research, The Hebrew University-Hadassah Medical School, Jerusalem, Israel; 3Endocrinology and Metabolism Service, Department of Internal Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

    Optimizing engraftment and early survival of human beta cells after clinical islet transplantation is critical to long-term function, but there are no reliable, quantifiable measures…
  • 2017 American Transplant Congress

    Post-Transplant Lymphoproliferative Disorder: Risk Analysis for Pancreas Transplant Patients.

    E. Minja, T. Dunn, A. Matas, T. Pruett, R. Kandaswamy, E. Finger.

    Dept of Surgery, University of Minnesota, Minneapolis, MN

    Objective: Determine incidence, risk factors, and impact of PTLD in pancreas transplantation (PTx).Methods: Retrospective review of all PTx performed between 7/25/1978 and 12/17/2015 at a…
  • 2017 American Transplant Congress

    Impact of Intensive Dosing of Mycophenolate on Pancreas Allograft Survival.

    J. Fose,1 K. Rolling,1 N. Menninga,1 G. Leverson,2 M. Jorgenson,1 J. Odorico,2 R. Robert.2

    1Pharmacy, UW Health, Madison, WI; 2Transplant Surgery, UW Health, Madison, WI

    Purpose: The primary objective was to evaluate the effect of mycophenolate (MPA) dicharge (DC) dose on pancreas allograft (PTX) survival. Secondary endpoints included patient survival…
  • 2017 American Transplant Congress

    Neurogenic Orthostatic Hypotension: An Iatrogenic Complication of Successful Pancreas Transplantation?

    S. Kuten,1 E. Simpson,1 A. Gaber,1 D. Nguyen,1 E. Graviss,1 S. Patel,2 R. Knight.1

    1Houston Methodist Hospital, Houston, TX; 2Veloxis Pharmaceuticals, Cary, NC

    Abrupt improvement in glycemic control is known to cause treatment-induced neuoropathies in poorly-controlled diabetes (DM).1 Similarly, neurogenic orthostatic hypotension (OH) is a well-known complication of…
  • 2017 American Transplant Congress

    Patterns and Associated Risk Factors for Early Readmissions Post Total Pancreatectomy and Islet Auto-Transplantation(TP-IAT).

    V. Kirchner, A. Bagdiwala, D. Vock, M. Bellin, G. Beilman, L. Berry, S. Chinnakotla, T. Dunn, M. Freeman, D. Sutherland, T. Pruett.

    University of Minnesota, Minneapolis

    Introduction: For four decades, TP-IAT has been performed to provide pain relief and preserve insulin function in patients(pts) with chronic/acute relapsing pancreatitis. Despite advances in…
  • 2017 American Transplant Congress

    Impact of Early Pancreas Graft Failure on Patient and Kidney Graft Survival After Simultaneous Pancreas and Kidney Transplantation (SPK).

    A. Gruessner, M. Laftavi, V. Whittaker, Z. Acun, O. Pankowycz, R. Gruessner.

    SUNY Upstate Medical University, Syracuse, NY

    Introduction: In SPK transplants, the major risk factors for poor patient survival are early pancreas and/or kidney graft loss. In this study, we specifically examined…
  • 2017 American Transplant Congress

    Association of BK and CMV Viremia with Pancreas Allograft Survival Among Adults Receiving Simultaneous Pancreas and Kidney Transplant: The Wisconsin Allograft Recipient Database (WisARD).

    F. Aziz, B. Astor, S. Parajuli, N. Garg, B. Muth, D. Mandelbrot, A. Djamali, D. Kaufman, J. Odorico, H. Sollinger, M. Mohamed.

    Department of Medicine, University of Wisconsin, Madison, WI

    Knowing impact of BKV viremia and CMV infection on pancreas allograft outcome post Simultaneous Pancreas and Kidney transplant (SPK) may improve allograft long-term survival and…
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