2017 American Transplant Congress
Post-Transplant Sensitization: Does it Make a Difference in the Development of First-Year Intimal Thickening?
Cedars-Sinai Heart Institute, Los Angeles
Background: The development of donor specific antibody (DSA) after heart transplantation has been reported to be associated with the development of cardiac allograft vasculopathy (CAV).…2017 American Transplant Congress
Retrospective Review of Early versus Late Initiation of Oral Sildenafil for Right Ventricular Dysfunction in Post-Cardiac Transplant Surgery Patients.
University Health Network, Toronto, Canada
Background: Right ventricular (RV) dysfunction is a serious complication that may occur after cardiac transplant and result in graft failure or death. Inotropes (i.e., epinephrine,…2017 American Transplant Congress
Severe Tricuspid Regurgitation After Heart Transplantation: Does It Require Surgical Repair?
Cedars-Sinai Heart Institute, Los Angeles
Background: Tricuspid regurgitation (TR) after heart transplantation is common. Causes for TR may be due to volume overload, flail tricuspid leaflet from endomyocardial biopsy, pulmonary…2017 American Transplant Congress
Improvement of Cyclosporine A Dosing Strategy to Enhance Medication Adherence.
Background: It is known that the number of daily pills is crucial for medical adherence of patients after heart transplantation (HTx). For cyclosporine A (CsA)…2017 American Transplant Congress
Timing, Frequency, and Precipitating Factors of Early Readmission After Heart Transplant.
University of Chicago Medicine, Chicago, IL
Purpose: Early hospital readmission after organ transplantation, defined as readmission within 30 days of discharge, has been found to be associated with increased morbidity and…2017 American Transplant Congress
NK Cells Respond to CMV Lysate by Inducing IFNγ and CD107a Surface Expression in an Antibody-Dependent Manner: This Represents a Cytokine Flow Cytometry (CFC) Assay That Could Assess Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) as a Marker of CMV Immunity in Transplant Recipients.
Background: Viral infections represent significant morbidity factors for transplant recipients. Tools to assess the efficacy of viral-specific responses are lacking. ADCC is the major antibody-mediated…2017 American Transplant Congress
CD40/CD40 Ligand Signal Controls Cytotoxic Ability of Natural Killer Cells After Invariant Natural Killer T Cell Stimulation.
Because iNKT cells have powerful immune-regulatory function, an administration of iNKT cell ligand; α-galactosylceramide (aGC) is one of the potent strategies for induction of transplant…2017 American Transplant Congress
Patterns of Monocyte Differentiation and Activation in a Non-Human Primate Model of Brain Death.
Surgery - Division of Transplantation, University of Wisconsin-Madison, Madison, WI
Brain-death (BD) induces a systemic inflammatory response known to impair tissue perfusion and promote graft immunogenicity. Monocytes play a significant role in the regulation of…2017 American Transplant Congress
A Novel Role for MyD88 Signaling Downstream from Toll-Like Receptors in B Cells Responding to Blood Group Antigens.
Hiroshima University, Hiroshima, Japan
[Introduction]Although there is some empirical evidence that severe infectious complications provoke refractory AMR following ABO-incompatible transplantations (ABOi-Tx), its mechanism remains unclear. Here, we investigated a…2017 American Transplant Congress
Reduced Expression of Membrane Complement Regulatory Protein CD59 on Leukocytes Following Lung Transplantation.
BackgroundCellular protection against unwanted complement activation is provided by expression of membrane-bound complement regulatory proteins including CD59. This protein prevents membrane attack complex formation and…
American Transplant Congress abstracts