Abstracts Archive - Page 106 of 1683 - ATC Abstracts

2022 American Transplant Congress
The Impact of Maintenance Immunosuppressive Regimen on COVID-19 Outcomes Among Kidney Transplant Patients
T. V. Sandes-Freitas¹, L. Modelli de Andrade², L. Requião-Moura³, J. Medina-Pestana³, H. Tedesco-Silva³, A. on behalf of Covid-19 KT Brazil Study Group¹
¹Universidade Federal do Ceará / Unidade Pesquisa Clínica CH-UFC/EBSERH, Fortaleza, Brazil, ²Universidade Estadual Paulista - UNESP, Botucatu, Brazil, ³Universidade Federal de São Paulo / Hospital do Rim, São Paulo, Brazil
*Purpose: Compared to azathioprine (AZA), mycophenolate (MPA) is implicated in an increased risk of several viral infections. Contrariwise, mTOR inhibitors (mTORi) are protective. Therefore, the…
2022 American Transplant Congress
Leveraging Single-Cell Signatures in Kidney Transplant Biopsies Uncovers Immunological Heterogeneity Within Rejection Phenotypes
J. Callemeyn¹, B. Lamarthée¹, P. Koshy², T. Debyser³, E. Van Loon¹, A. Franken⁴, T. Van Brussel⁴, I. Arijs⁴, D. Lambrechts⁴, M. Rabant⁵, A. Senev¹, T. Vaulet⁶, C. Tinel¹, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²Department of Morphology and Molecular Pathology, University Hospitals Leuven, Leuven, Belgium, ³Faculty of Medicine, KU Leuven, Leuven, Belgium, ⁴Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium, ⁵Necker-Enfants Malades Institute, Institut national de la santé et de la recherche médicale (Inserm), Université de Paris, Paris, France, ⁶ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
*Purpose: Rejection of the kidney allograft is hallmarked by the accumulation of inflammatory cells within the renal architecture, leading to microvascular or tubulointerstitial inflammation. However,…
2022 American Transplant Congress
Axl and MerTK Regulate the Activation of Liver Ischemia Reperfusion Injury by Upregulating Il-13 in Kupffer Cells
J. Zhang¹, M. Ni¹, H. Zhang¹, R. Busuttil¹, J. Kupiec-Weglinski¹, X. Wang², J. Jin³, Y. Zhai¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, ³Guilin Medical University, Guilin, China
*Purpose: Ischemia reperfusion injury (IRI) remains an unresolved clinical problem. A sterile inflammatory response drives the disease pathogenesis. Although mechanisms of liver innate immune activation…
2022 American Transplant Congress
Renal Transplantation and Statins Effects on Dyslipidemia in Renal Transplant Recipients
Z. Arabi, A. Alghamdi, A. Alnasrullah, A. R. Altheaby, M. Tawhari, N. Alnazari
KAMC, Riyadh, Saudi Arabia
*Purpose: to review the effect of renal transplantation and adding of statins on dyslipidemia in renal transplant recipients.*Methods: A single center experience retrospective study of…
2022 American Transplant Congress
The US Kidney Allocation System Should Not Allocate En Bloc Kidneys from Deceased Donors < 18 Kg as Equivalent to Top 20% KDPI Single Kidneys
W. F. Parker¹, A. Gallo², L. Ross¹
¹University of Chicago, Chicago, IL, ²Stanford University, Palo Alto, CA
*Purpose: In December 2020, the US Kidney Allocation System (KAS) revised the allocation rules for deceased donors under 18 kg, stating that both kidneys must…
2022 American Transplant Congress
Impact of Recipient Obesity on Kidney Transplantation Outcome: A Retrospective Cohort Study with a Matched Comparison
A. Buemi
Surgery, Cliniques Universitaires Saint Luc, Bruxelles, Belgium
*Purpose: The aim of this study was to evaluate the effect of recipient obesity on posttransplant complications and patient and graft survival.*Methods: A single-institution, retrospective…
2022 American Transplant Congress
Poor Prognosis of Proliferative Glomerulonephritis with Monoclonal IgG Deposits in Renal Allografts: A Retrospective Multicenter Study from China
Q. Wu¹, D. Liang¹, X. Ni¹, T. Song², X. Wu³, M. Zhang¹, J. Chen¹, D. Cheng¹, W. Jiqiu¹
¹National Clinical Research Center of Kidney Diseases, Jinling Hospital,Nanjing University Jinling School of Medicine, Nanjing, China, ²Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China, ³Department of Urology, Henan Provincial People's Hospital; Zhengzhou University People's Hospital, Zhengzhou, China
*Purpose: To analyze the clinicopathological characteristics, treatment efficacy and prognosis of proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) in renal allografts from multi-centers in China.*Methods:…
2022 American Transplant Congress
Variation in Donor Liver Rejection Rates for Donor Quality Among US Transplant Centers
M. Anderson¹, T. Gilbert², M. Englesbe¹, S. Waits¹
¹Michigan Medicine Transplant Center, Ann Arbor, MI, ²University of Michigan Medical School, Ann Arbor, MI
*Purpose: Optimal utilization of all viable donor livers is a public health imperative. As no standardized criteria exist for assessment of donor quality, differential utilization…
2022 American Transplant Congress
A Model for Medical Device Innovation in Transplantation: Using the Biodesign Process to Address the Impact of Warm Ischemic Injury
K. Hansen¹, J. Wall²
¹University of California San Francisco, San Francisco, CA, ²Stanford University, Palo Alto, CA
*Purpose: The impact of warming during second warm-ischemia (anastomosis) of kidney transplantation has been increasingly recognized in the literature. The outsized effect on delayed graft…
2022 American Transplant Congress
Bioink Based on the DECM for 3D-Bioprinting of Bionic Pancreas – First Results of Animal
M. Klak¹, K. Kosowska¹, T. Bryniarski¹, I. Lojszczyk¹, T. Dobrzanski², G. Tymicki¹, A. Filip¹, A. A. Szczepankiewicz³, R. Olkowski⁴, A. Kosowska⁴, A. Berman¹, A. Kaminski⁴, M. Wszola¹
¹Foundation of Research and Science Development, Warsaw, Poland, ²Polbionica LTD, Warsaw, Poland, ³Institute of Experimental Biology M. Nencki PAN, Warsaw, Poland, ⁴Medical University of Warsaw, Warsaw, Poland
*Purpose: Tissue engineering is an interdisciplinary field involving activities based on two interrelated areas: developing new methods to repair, regenerate and replace damaged tissues and…