Abstracts Archive - Page 105 of 1683 - ATC Abstracts

2022 American Transplant Congress
Axl and MerTK Regulate the Activation of Liver Ischemia Reperfusion Injury by Upregulating Il-13 in Kupffer Cells
J. Zhang¹, M. Ni¹, H. Zhang¹, R. Busuttil¹, J. Kupiec-Weglinski¹, X. Wang², J. Jin³, Y. Zhai¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, ³Guilin Medical University, Guilin, China
*Purpose: Ischemia reperfusion injury (IRI) remains an unresolved clinical problem. A sterile inflammatory response drives the disease pathogenesis. Although mechanisms of liver innate immune activation…
2022 American Transplant Congress
Sirolimus Regimens After Kidney Transplantation: Role of Pre-Transplant Risk Factors in Modifying the Risk of Mortality in Adult Recipients
A. Santos¹, H. Ibrahim¹, M. A. Leghrouz¹, X. Wen²
¹University of Florida, Gainesville, FL, ²University of Rhode Island, Kinston, RI
*Purpose: We aimed to investigate the role of risk factors in modifying the association of sirolimus with mortality in kidney transplant (KT) recipients (KTRs).*Methods: Using…
2022 American Transplant Congress
Impact of Donor-to-Recipient Body Surface Area Ratio on Graft Survival and Mortality Following Deceased Donor Liver Transplants
S. Radomski, L. Zeiser, A. Massie, S. Ottmann, D. Segev, E. King
Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: The impact of size mismatch on graft survival in living donor liver transplant is well established but is not a common concern in deceased…
2022 American Transplant Congress
ESRD is Increasing Faster After Living Kidney Donation Than it Does in the Unselected US Population: A New Risk Metric?
R. W. Steiner
UCSD School of Medicine, San Diego, San Diego, CA
*Purpose: ESRD rates increase exponentially both after kidney donation and as the US population ages. Increases in ESRD rates from the first to the second…
2022 American Transplant Congress
Leveraging Single-Cell Signatures in Kidney Transplant Biopsies Uncovers Immunological Heterogeneity Within Rejection Phenotypes
J. Callemeyn¹, B. Lamarthée¹, P. Koshy², T. Debyser³, E. Van Loon¹, A. Franken⁴, T. Van Brussel⁴, I. Arijs⁴, D. Lambrechts⁴, M. Rabant⁵, A. Senev¹, T. Vaulet⁶, C. Tinel¹, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²Department of Morphology and Molecular Pathology, University Hospitals Leuven, Leuven, Belgium, ³Faculty of Medicine, KU Leuven, Leuven, Belgium, ⁴Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium, ⁵Necker-Enfants Malades Institute, Institut national de la santé et de la recherche médicale (Inserm), Université de Paris, Paris, France, ⁶ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium
*Purpose: Rejection of the kidney allograft is hallmarked by the accumulation of inflammatory cells within the renal architecture, leading to microvascular or tubulointerstitial inflammation. However,…
2022 American Transplant Congress
Donor and Recipient Age Matching for Kidney Transplantation: A Machine Learning Approach
J. Kim, J. Ahn, A. Massie, D. Segev, S. Bae
Johns Hopkins, Baltimore, MD
*Purpose: Under the concept of ‘longevity matching,’ the Kidney Allocation System favors matching younger deceased donors with younger kidney transplant (KT) candidates. However, it remains…
2022 American Transplant Congress
Evolution of the Need for Transplant Evaluations for Liver Failure Decompensation After TIPS
N. Kemmer¹, V. Sureshkumar², L. Grater³, G. Hoots⁴, S. Agrawal¹, K. Robichaux⁵, M. Gosselin³, S. Mohammed⁵, A. Kumar⁶, J. Buggs⁷
¹Transplant Hepatology, Tampa General Hospital, Tampa, FL, ²Lake Erie College of Osteopathic Medicine, Bradenton, FL, ³University of Tampa, Tampa, FL, ⁴Radiology, Tampa General Hospital, Tampa, FL, ⁵University of South Florida, Tampa, FL, ⁶Morsani College of Medicine, University of South Florida, Tampa, FL, ⁷Transplant Surgery, Tampa General Hospital, Tampa, FL
*Purpose: Portal hypertension is described as an increased pressure gradient between the portal and systemic circulation which can result in severe complications. Transjugular Intrahepatic Portosystemic…
2022 American Transplant Congress
Dietary Sodium Intake And Blood Pressure In Living Kidney Donors (SPLID): Rationale And Design Of A Pilot Single-center Crossover Single-blind Randomized Controlled Trial
E. Tantisattamo¹, U. G. Reddy¹, A. J. Ferrey¹, H. Ichii², D. C. Dafoe², H. Moradi¹, C. M. Rhee¹, K. Kalantar-Zadeh¹
¹Division of Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, University of California Irvine School of Medicine, Orange, CA, ²Division of Kidney and Pancreas Transplantation, Department of Surgery, University of California Irvine School of Medicine, Orange, CA
*Purpose: Since living kidney donors(LKD) are generally healthy and non-hypertensive individuals, non-pharmacologic interventions are likely to be an acceptable and practical approach to preventing hypertension(HTN).…
2022 American Transplant Congress
Histologic Predictors of Graft Loss in Early Clinically Indicated Biopsies After Kidney Transplantation
M. Ajaimy¹, V. Hemmige², L. E. Liriano-Ward³, Y. Azzi¹, S. Kapoor⁴, P. Loarte¹, C. Pynadath⁵, A. Colovai¹, E. Akalin⁶
¹Einstein-Montefiore Transplant Center, Bronx, NY, ²Montefiore Medical Center, Bronx, NY, ³Transplant, Montefiore Medical Center, Bronx, NY, ⁴Montefiore Medical Center, New York, NY, ⁵Einstein-Montefiore Transplant Center, Scarsdale, NY, ⁶Albert Einstein College of Medicine, Montefiore Medical Ctr, Bronx, NY
*Purpose: We aimed to investigate histopathological predictors of graft lost in patients who underwent clinically indicated biopsies for worsening kidney function and/or proteinuria within 3…
2022 American Transplant Congress
Costs Associated with Induction Therapy for Pediatric Kidney Transplantation
N. M. Rodig¹, H. Pizzo², D. Levy Erez³, T. Richardson⁴, M. Somers¹
¹Boston Children's Hospital, Boston, MA, ²Cedars-Sinai Medical Center, Los Angeles, CA, ³Children’s Hospital of Philadelphia, Philadelphia, PA, ⁴Children's Hospital Association, Lenexa, KS
*Purpose: Choice of induction agent for pediatric kidney transplantation (KTx) is often based upon patient characteristics and center practice; costs associated with this choice have…