Abstracts Archive - Page 103 of 1683 - ATC Abstracts

2022 American Transplant Congress
Does Machine Perfusion of Heart for Donation After Cardiac Death (DCD) Transplantation Affect Other Organ Outcomes?
R. Misawa¹, K. Okumura², H. Sogawa¹, G. Veillette¹, A. Dhand³, R. Bodin⁴, D. C. Wolf⁴, B. Partiula⁴, D. John¹, T. Diflo⁵, S. Nishida¹
¹Department of Surgery, Transplant, Westchester Medical Center/New York Medical College, Valhalla, NY, ²Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY, ³Department of Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY, ⁴Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY, ⁵Westchester Medical Center/New York Medical College, Valhalla, NY
*Purpose: Machine perfusion of heart for donation after cardiac death (DCD) transplants is being increasingly utilized. Initial protocol of the heart machine perfusion for the…
2022 American Transplant Congress
Risk of Clostridioides Difficile Infection After Kidney Transplant
C. Thomas¹, B. Crowther², K. Schwarz², D. Chen¹, Y. Shandaliy¹, K. Johnson¹, P. Klem²
¹Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Anschutz Medical Campus, Aurora, CO, ²Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Hospital System, Aurora, CO
*Purpose: For patients undergoing kidney transplant, the risk of developing Clostridioides difficle infection (CDI) is reported to be 4.7%, likely due to risk factors such…
2022 American Transplant Congress
Can We Predict Progression of Potential Donation After Cardiac Death Donors (DCD) Using DonorNet?
Y. Bababekov¹, A. Yule¹, H. Moore¹, R. Choudhury², C. Hertert³, T. Pshak⁴, T. Nydam⁵, B. Kaplan¹, E. Pomfret¹, J. Pomposelli⁵
¹Transplant Surgery, University of Colorado, Aurora, CO, ²University of Colorado Hospital, Denver, CO, ³Donor Alliance, Denver, CO, ⁴University of Colorado, Denver, CO, ⁵University of Colorado, Aurora, CO
*Purpose: DCD utilization of livers is limited by unpredictability of progression, perceived worse outcome, and costs related to deployment of resources. We aimed to predict…
2022 American Transplant Congress
Dual Deceased Donor Kidney Transplants: Maximizing Utilization of Suboptimal Kidneys
S. Nagaraju, S. Vaishnav, K. Boggs, T. Cook, A. Jones, J. B. Africa
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: To demonstrate that dual transplant of marginal kidneys is an underutilized strategy to minimize discard rates and mitigate organ shortage.*Methods: We compared dual kidney…
2022 American Transplant Congress
Superoxide in Cardiac Allografts from Donors After Circulatory Death
M. Urban¹, T. Bruett², K. F. Duncan¹, N. W. Markin³, M. M. Chacon³, M. C. Zimmerman⁴
¹Department of Surgery. Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE, ²College of Medicine. Department of Cellular and Integtrative Physiology., University of Nebraska Medical Center, Omaha, NE, ³Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, ⁴Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE
*Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…
2022 American Transplant Congress
Size to Fit: A Simple Formula to Predict Donor Liver Weight in Deceased Donor Liver Transplant
A. Mohamed¹, J. Cui², T. Kitajima¹, T. Shamaa¹, T. Ivanics¹, I. Godana³, A. Yorks², S. Shimada¹, B. Madek¹, M. Rizzari¹, A. Yoshida¹, M. Abouljoud¹, S. Nagai¹, K. Collins¹
¹Henry Ford Transplant Institute, Detroit, MI, ²Wayne State University School of Medicine, Detroit, MI, ³General Surgery, McLaren, Lansing, MI
*Purpose: Estimated donor liver volume (DLV) prediction equations are widely published. However, they often are complex and underpredict DLV, particularly in non-ideal body weight donors.…
2022 American Transplant Congress
Sirolimus Regimens After Kidney Transplantation: Role of Pre-Transplant Risk Factors in Modifying the Risk of Mortality in Adult Recipients
A. Santos¹, H. Ibrahim¹, M. A. Leghrouz¹, X. Wen²
¹University of Florida, Gainesville, FL, ²University of Rhode Island, Kinston, RI
*Purpose: We aimed to investigate the role of risk factors in modifying the association of sirolimus with mortality in kidney transplant (KT) recipients (KTRs).*Methods: Using…
2022 American Transplant Congress
Single Cell RNAseq Analysis of Liver Transplant Rejection Reveals Highly Restricted TCR Clonal Expansion of Tissue-Resident Memory CD8⁺ T Cells That Persist Despite Corticosteroids and ATG Therapy
A. L. Peters¹, G. Begum¹, K. Roskin², E. Woodle³, D. Hildeman⁴
¹Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Department of Bioinformatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Department of Surgery, University of Cincinnati, Cincinnati, OH, ⁴Department of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: Conventional therapy for liver transplant rejection (corticosteroids and ATG) has remained unchanged for six decades, and is not infrequently met with treatment failure. Here,…
2022 American Transplant Congress
Chronic Ethanol Exposure Prolongs Murine Allograft Survival
D. Swift, M. Ford, W. Kitchens
Department of Surgery, Emory University, Atlanta, GA
*Purpose: Alcoholic liver disease is the leading indication for liver transplantation in the United States, and patients are increasingly transplanted without the traditional six month…
2022 American Transplant Congress
Waitlisted and Transplant Patient Perspectives on Expanding Access to Deceased Donor Kidney Transplants
C. Rosaasen¹, N. Rosaasen², R. Mainra³, A. Trachtenberg⁴, J. Ho⁵, C. Parsons⁶, S. Delaney⁶, H. Mansell⁷
¹Johnson Shoyama School of Public Policy, University of Saskatchewan, Saskatoon, SK, Canada, ²Saskatchewan Transplant Program, Saskatchewan Health Authority, Saskatoon, SK, Canada, ³Division of Nephrology, Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada, ⁴, Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada, ⁵Department of Internal Medicine and Department of Immunology, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada, ⁶Canadian Blood Services, Edmonton, AB, Canada, ⁷University of Saskatchewan, Saskatoon, SK, Canada
*Purpose: A concerning number of kidneys (expanded donor criteria, extended criteria, or marginal kidneys) are discarded yearly, and novel solutions are needed to solve the…