ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Final Report of the Use of α-Lipoic Acid in Liver Transplantation to Prevent Ischemia Reperfusion Injury

    P. C. Casciato1, N. Ambrosi2, F. Caro2, L. Oliveira1, F. Zalazar1, A. Garmendia1, M. Bonifacio1, M. Padilla1, J. Paladini1, J. Di Menno1, J. Pekjol1, E. de Santibañes1, M. de Santibañes1, G. Adrian1, C. Incardona1, E. Chuluyan2

    1Hospital Italiano, Buenos Aires, Argentina, 2CEFYBO, Buenos Aires, Argentina

    *Purpose: The ischemia and reperfusion injury contributs to grafts deterioration and adverse post-transplant outcomes. The aim of the present study was to evaluate the safety…
  • 2022 American Transplant Congress

    Escalating Waitlist Mortality Above MELD 40: A Rationale to Uncap MELD 3.0?

    A. Kwong, A. Mannalithara, W. Kim

    Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA

    *Purpose: MELD 3.0 is a recently proposed model that improves upon MELD-Na, incorporating sex and albumin as additional variables, updating existing coefficients and adding relevant…
  • 2022 American Transplant Congress

    Impact of Target Tacrolimus Levels on BK Polyomavirus DNAemia and Allograft Rejection Among Pediatric Kidney Transplant Recipients

    H. Huang1, P. Winterberg1, R. George1, A. Serluco2, R. Liverman2, I. Yildirim3, R. Garro1

    1Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, 3Yale University School of Medicine, New Haven, CT

    *Purpose: BK Polyomavirus (BK) DNAemia is a serious and common infectious complication after kidney transplant (KT). We evaluated the impact of targeting lower tacrolimus levels…
  • 2022 American Transplant Congress

    Sirolimus Regimens After Kidney Transplantation: Role of Pre-Transplant Risk Factors in Modifying the Risk of Mortality in Adult Recipients

    A. Santos1, H. Ibrahim1, M. A. Leghrouz1, X. Wen2

    1University of Florida, Gainesville, FL, 2University of Rhode Island, Kinston, RI

    *Purpose: We aimed to investigate the role of risk factors in modifying the association of sirolimus with mortality in kidney transplant (KT) recipients (KTRs).*Methods: Using…
  • 2022 American Transplant Congress

    Timing of Hypotension Post Kidney Transplant Impacts the Risk of Subsequent Delayed Graft Function

    S. A. Morrison1, A. Thanamayooran2, K. Tennankore1, A. J. Vinson1

    1Dalhousie University, Halifax, NS, Canada, 2Nova Scotia Health Authority, Halifax, NS, Canada

    *Purpose: Hypotension is common post-kidney transplant and is associated with delayed graft function (DGF; a need for dialysis in the first week post-transplant) and prolonged…
  • 2022 American Transplant Congress

    ESRD is Increasing Faster After Living Kidney Donation Than it Does in the Unselected US Population: A New Risk Metric?

    R. W. Steiner

    UCSD School of Medicine, San Diego, San Diego, CA

    *Purpose: ESRD rates increase exponentially both after kidney donation and as the US population ages. Increases in ESRD rates from the first to the second…
  • 2022 American Transplant Congress

    Functional Recellularized Patient Derived Endothelium; A Human Vascular Graft Approach

    H. Tejeda Mora1, J. Willemse2, Y. den Hartog1, I. Schurink2, M. M. Verstegen2, J. de Jonge2, R. C. Minnee2, M. W. van den Hoogen2, C. C. Baan1, L. J. van der Laan2, M. J. Hoogduijn1

    1Transplant Institute - Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands, 2Transplant Institute - Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: In transplantation, the endothelial lining is the first barrier between the donor organ and recipient immune system. Damaged endothelium exposes extracellular matrix (ECM) molecules…
  • 2022 American Transplant Congress

    Superoxide in Cardiac Allografts from Donors After Circulatory Death

    M. Urban1, T. Bruett2, K. F. Duncan1, N. W. Markin3, M. M. Chacon3, M. C. Zimmerman4

    1Department of Surgery. Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE, 2College of Medicine. Department of Cellular and Integtrative Physiology., University of Nebraska Medical Center, Omaha, NE, 3Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, 4Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE

    *Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…
  • 2022 American Transplant Congress

    Dual Deceased Donor Kidney Transplants: Maximizing Utilization of Suboptimal Kidneys

    S. Nagaraju, S. Vaishnav, K. Boggs, T. Cook, A. Jones, J. B. Africa

    Renal Transplant, Charleston Area Medical Center, Charleston, WV

    *Purpose: To demonstrate that dual transplant of marginal kidneys is an underutilized strategy to minimize discard rates and mitigate organ shortage.*Methods: We compared dual kidney…
  • 2022 American Transplant Congress

    Can We Predict Progression of Potential Donation After Cardiac Death Donors (DCD) Using DonorNet?

    Y. Bababekov1, A. Yule1, H. Moore1, R. Choudhury2, C. Hertert3, T. Pshak4, T. Nydam5, B. Kaplan1, E. Pomfret1, J. Pomposelli5

    1Transplant Surgery, University of Colorado, Aurora, CO, 2University of Colorado Hospital, Denver, CO, 3Donor Alliance, Denver, CO, 4University of Colorado, Denver, CO, 5University of Colorado, Aurora, CO

    *Purpose: DCD utilization of livers is limited by unpredictability of progression, perceived worse outcome, and costs related to deployment of resources. We aimed to predict…
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