ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Impact of Graft Type, Presence and Type of Inflammatory Bowel Disease on Outcomes Following Liver Transplantation for Primary Sclerosing Cholangitis

    S. Kumar1, S. Lin2, J. D. Schold3

    1Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, 2Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, 3Center for Populations Health Research, Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: In Primary sclerosing cholangitis (PSC), concerns exist regarding outcomes following donation after circulatory death (DCD) liver transplantation (LT) due to risk of ischemic cholangiopathy…
  • 2022 American Transplant Congress

    Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)

    D. J. Reich1, A. Schlegel2, M. Rizzari3, D. Foley4, M. DeVera5, W. Chapman6, G. Roll7, A. Saharia8, C. Quintini9, S. Florman10, S. Merani11, S. Mao12, A. Pinna13, M. Akoad14, C. Kubal15, S. Alexopoulos16, H. Bohorquez17

    1Drexel University, Philadelphia, PA, 2Careggi U, Florence, Italy, 3Henry Ford, Detroit, MI, 4U Wisconsin, Madison, WI, 5Loma Linda, Loma Linda, CA, 6Washington U, Saint Louis, MO, 7UCSF, SF, CA, 8Methodist, Houston, TX, 9Cleveland Clinic, Cleveland, OH, 10Mount Sinai, NY, NY, 11U Nebraska, Omaha, NE, 12Mayo, Jacksonville, FL, 13Cleveland Clinic, Weston, FL, 14Lahey, Burlington, MA, 15Indiana U, Indianapolis, IN, 16Vanderbilt, Nashville, TN, 17Ochsner, New Orleans, LA

    *Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…
  • 2022 American Transplant Congress

    Single Nuclei RNA-Sequencing Identifies Distinct Immune Cell Profile in Kidney Allograft Fibrosis

    J. McDaniels1, A. Shetty1, C. Kuscu2, C. Kuscu2, T. Rousselle1, E. Bardhi1, C. Drachenberg1, M. Talwar2, J. Eason2, T. Muthukumar3, D. Maluf1, V. Mas1

    1University of Maryland Baltimore, Baltimore, MD, 2UTHSC, Memphis, TN, 3Weill Cornell Medicine, New York, NY

    *Purpose: A major obstacle after kidney transplantation (KT) is chronic allograft dysfunction characterized by interstitial fibrosis and tubular atrophy (IFTA). Despite extensive research, the cellular…
  • 2022 American Transplant Congress

    Cold Ischemic Time and Kidney Graft Failure; Mediation Through Delayed Graft Function

    J. Miller1, W. Irish2, D. Sawinski3, A. Massie4, J. Snyder1

    1Scientific Registry of Transplant Recipients, Minneapolis, MN, 2Department of Surgery, East Carolina University, Greenville, NC, 3Division of Nephrology and Hypertension, Weill Cornell Medical College, New York, NY, 4Division of Surgery, Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Delayed graft function (DGF) has been associated with decreased graft survival and prolonged cold ischemia time (CIT) has been proposed as a modifiable DGF…
  • 2022 American Transplant Congress

    Chronic Ethanol Exposure Prolongs Murine Allograft Survival

    D. Swift, M. Ford, W. Kitchens

    Department of Surgery, Emory University, Atlanta, GA

    *Purpose: Alcoholic liver disease is the leading indication for liver transplantation in the United States, and patients are increasingly transplanted without the traditional six month…
  • 2022 American Transplant Congress

    Health Care Transition of Adolescents After Kidney Transplantation in Germany and Austria – The Randomized Controlled Transnephro Trial

    L. Pape1, M. Kreuzer1, A. Großhenig2, J. Prüfe1, S. Group3

    1Pediatrics II, University Hospital of Essen, Essen, Germany, 2Biostatistics, Hannover Medical School, Hannover, Germany, 3German Society of Pediatric Nephrology, Berlin, Germany

    *Purpose: Adolescence is the age with the highest rate of graft losses because of non-adherence and the transfer from pediatric to adult care. Health care…
  • 2022 American Transplant Congress

    Decellularized Human Pancreatic Extracellular Matrix-Based Physiomimetic Microenvironment for Human Islet Culture

    A. Asthana1, D. Chaimov1, R. Tamburrini2, S. J. Walker3, G. Orlando1

    1Wake Forest Baptist Medical Center, Winston-Salem, NC, 2University of Wisconsin Hospital and Clinics, Madison, WI, 3Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC

    *Purpose: Maintenance of human islet viability and function ex vivo can be a significant bottleneck for both regenerative medicine as well as tissue engineering applications.…
  • 2022 American Transplant Congress

    Stem Cell Donor-Derived CPRA Better Reflects Sensitization Than Current CPRA

    K. Lindblad1, C. Murphey2, P. Lalli3, J. Lunz4, L. Gragert5

    1UNOS, Richmnd, VA, 2Southwest Immunodiagnostics, Inc., San Antonio, TX, 3Carolinas Medical Center, Charlotte, NC, 4LifeLink Foundation Transplant Immunology Lab, Tampa, FL, 5Tulane University School of Medicine, New Orleans, LA

    *Purpose: The OPTN Histocompatibility Committee proposes replacing the current calculated panel reactive antibody (CPRA), based on HLA haplotype frequencies from ~14,000 deceased kidney donors, with…
  • 2022 American Transplant Congress

    Long-Term Outcomes of Liver Transplantation (LT) Using Grafts from Donors with Active and Chronic Hepatitis B Virus (HBV) Infection; Multi-Center Cohort Study

    S. Suh1, S. Gang2, Y. Choi2, S. Hong2, N. Yi2, K. Lee2, K. Suh2

    1Chung-Ang University, Seoul, Korea, Republic of, 2Seoul National University, Seoul, Korea, Republic of

    *Purpose: Liver grafts from donors with hepatitis B infection contributed to expand the donor pool under the Hepatitis B immunoglobulin (HBIG) and antiviral agents (NA:…
  • 2022 American Transplant Congress

    Resource Utilization in Liver Transplant Patients Based on Psychological Evaluation of High Risk vs. Non-High Risk

    K. Barber1, D. Chism2, R. Sauls3, R. Shargo3, M. Gosselin4, S. Mohammed3, K. Robichaux3, A. Kumar5, J. Buggs1

    1Transplant Surgery, Tampa General Hospital, Tampa, FL, 2Lake Erie College of Osteopathic Medicine, Bradenton, FL, 3University of South Florida, Tampa, FL, 4University of Tampa, Tampa, FL, 5Morsani College of Medicine, University of South Florida, Tampa, FL

    *Purpose: Psychological evaluation in liver transplant candidates helps to determine suitability. The psychological risk assessment results in the characterization of either low, medium, or high…
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