Outcomes in Non-A1 and Non A1 B to B Deceased Donor Renal Transplantation Are Comparable to B Donor Renal Transplants

A. Brar, L. Kwon, A. Gruessner, F. Tedla, R. Gruessner, N. Sumrani, D. John, J. Renz, M. O. Salifu

SUNY Downstate Medical Center, Brooklyn, NY

Meeting: 2019 American Transplant Congress

Abstract number: 22

Keywords: Cadaveric organs, Kidney, Outcome, Public policy

Session Information

Session Name: Concurrent Session: Kidney Donor Selection / Management Issues I

Session Type: Concurrent Session

Date: Sunday, June 2, 2019

Session Time: 2:30pm-4:00pm

Presentation Time: 3:06pm-3:18pm

Location: Ballroom C

*Purpose: Blood type B patients wait longer to get deceased donor (DD) renal transplants compared to other blood types. On December 2014, the US national kidney allocation system (KAS) began to allocate kidneys from A2 and A2B (non-A1 and non-A1B) deceased donors (DD) into blood group B candidates. The primary objective of this study was to determine the patient and graft survival in B recipients who received A2/A2B blood type DD since the institution of the new kidney allocation system.

*Methods: Using the United Network for Organ Sharing (UNOS) database, B donors during 2014 to 2017 were analyzed. Using Kaplan-Meier and Cox proportional hazards adjusting for covariates, renal allograft and patient survival rates were computed.

*Results: From 2014 to 2017, there were 6,162 adult blood group B DD transplants. Of which A2 donors were 411, A2B 114, and 5332 received B blood type DD renal transplant. One and two year renal allograft survival in A2 donor was (95.4%, 91.6%), in A2B donor (96.2%, 96.2%) and B donor (93.4% vs 89.7%) respectively (Figure 1). One and two year patient survival in A2 donor was (97.1%, 95.1%), in A2B donor (97.4%, 97.4%), and B donor (96.1% vs 93.8%) respectively. Median wait time for B blood type was reduced from 35.2 months in 2014 to 27.6 months in 2017.

*Conclusions: Blood type B recipients who receive DD renal transplants from A2 or A2B transplants have similar patient and graft survival versus B type donors. Median wait time was reduced for B blood type renal transplant recipients due to change in allocation policy.

To cite this abstract in AMA style:

Brar A, Kwon L, Gruessner A, Tedla F, Gruessner R, Sumrani N, John D, Renz J, Salifu MO. Outcomes in Non-A1 and Non A1 B to B Deceased Donor Renal Transplantation Are Comparable to B Donor Renal Transplants [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/outcomes-in-non-a1-and-non-a1-b-to-b-deceased-donor-renal-transplantation-are-comparable-to-b-donor-renal-transplants/. Accessed November 22, 2024.

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