ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Living and Deceased Donor Uterus Transplantation – The 2-Arm Czech Uterus Transplant Trial: The First Year Report with Four Cases Done so Far.

J. Fronek,1 R. Chmel,2 L. Janousek,1 M. Novackova,2 J. Matecha,2 M. Olausson.3

1Transplant Surgery Department, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic
2Gynecology Department, University Motol Hospital, Prague, Czech Republic
3Department of Surgery, Sahlgrenska University, Goteborg, Sweden

Meeting: 2017 American Transplant Congress

Abstract number: 98

Keywords: Donation, Donors, unrelated

Session Information

Session Name: Concurrent Session: VCA

Session Type: Concurrent Session

Date: Sunday, April 30, 2017

Session Time: 2:30pm-4:00pm

 Presentation Time: 2:54pm-3:06pm

Location: E270

Introduction: Uterus transplantation (UTx) may become another organ transplantation. There is very limited worldwide experience so far. The Czech uterus transplant trial started in 2015. The first UTx case we performed on 30th April 2016.

Method: The plan is for 20 uterus transplant procedures in total, of those 10 from life and 10 from deceased donors.

Sample cases: Case one: The live donor was the recipients mother, age of 53, history of two deliveries, underwent open hysterectomy via low midline incision, surgery took 5:23, the postoperative course was uneventful. The recipient with MRKG syndrome, age of 30, was transplanted in sequence, orthotropic transplantation via low midline incision took 3:29, uterine arteries and ovarian veins were anastomosed to iliac vessels. After protocol cervix biopsy on day 9 the patient was discharged from the hospital. Now the patient is already on Tacrolimus monotherapy, early next year we plan the first embryo transfer.

Sample case two: Deceased-donor uterus transplantation: The recipient did not have the compatible live donor, so was activated on deceased donor waiting list. On 31st August 2016 she received uterus from deceased donor. The postoperative course was same uneventful as in the live donor case. Both recipients are having regular follow up including cervix biopsies.

Results: The first transplant case was from live donor, performed on 30th April 2016. Second case in the study and first one from deceased donor followed shortly, graft thrombosed and removed on 7th postoperative day. Third case was from deceased donor, first ever in world from nulipara deceased donor, this case is fine, currently the only one out of four performed in world from deceased donor, which is still in place and awaiting emryostransfer. Last case was on 19th November, from live donor, doing well. Two more cases will follow shortly.

Conclusions: The UTx is still very novel method. From each case we keep learning. Uterus is the organ, where we cannot measure any function after the transplant. Also, visualizing the perfusion with Doppler ultrasound is not easy. Immunosuppression is based on induction, early steroid withdrawal, MMF withdrawal at 6 months and long-term Tacrolimus monotherapy maintenance.

CITATION INFORMATION: Fronek J, Chmel R, Janousek L, Novackova M, Matecha J, Olausson M. Living and Deceased Donor Uterus Transplantation – The 2-Arm Czech Uterus Transplant Trial: The First Year Report with Four Cases Done so Far. Am J Transplant. 2017;17 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Fronek J, Chmel R, Janousek L, Novackova M, Matecha J, Olausson M. Living and Deceased Donor Uterus Transplantation – The 2-Arm Czech Uterus Transplant Trial: The First Year Report with Four Cases Done so Far. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/living-and-deceased-donor-uterus-transplantation-the-2-arm-czech-uterus-transplant-trial-the-first-year-report-with-four-cases-done-so-far/. Accessed May 10, 2025.

« Back to 2017 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences