Session Name: Poster Session A: Kidney Living Donor: Selection
Session Type: Poster Session
Date: Saturday, May 30, 2020
Session Time: 3:15pm-4:00pm
Presentation Time: 3:30pm-4:00pm
*Purpose: Although the data supporting long-term safety of nephrectomy in hypertensive donors has been reported, there is scarcity of long term data on the recipient outcomes of such donors. Furthermore the use of older (>60 year) hypertensive donors is even further rare and minimal data exists on the transplant recipient outcomes for these donors. Hence the purpose of our study was to study the demographics of older living donors and their recipient outcomes in the United States.
*Methods: The United States UNOS database was retrospectively reviewed for the purposes of our study for the period January 2000 through Decemeber 2016. We excluded pediatric and multi-organ transplant recipients and limited the time period to minimum one year follow up.
*Results: Out of 111,483 Living Donors during the study period, we identified 5,695 (5.1%) Living Donor Transplants with a donor age => 60 years that met our criteria. Median Follow up was 4.6 years. Out of these 531 (9.3%) were HTN donors.
There was no difference in all-cause unadjusted graft survival between recipients with Older HTN vs non-HTN donors (p=0.57), or death censored graft survival (p=0.79) or patient survival (p=0.52). Similarly there was no difference in graft survival between these two groups for race, gender, on dialysis, DGF, acute rejection . In the HTN Living Donor Group, there was no difference in graft survival between recipient races, genders, donor races and acute rejection. Graft Survival was inferior in donors > 65 (p=0.0005), as well as HTN vs non-HTN donors (p=0.035) as compared to donors age 60-64 years.
*Conclusions: Transplant Recipient outcomes from Older hypertensive living donors are favorable and comparable to those donors without HTN. Careful selection of such donors and matching to appropriate recipients should not be discouraged when such donors are available.
To cite this abstract in AMA style:Sharfuddin A, Taber T, Adebiyi O, Panezai M, Mishler D, Yaqub M. Kidney Transplant Recipient Outcomes from Older (60+) Hypertensive Living Donors [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/kidney-transplant-recipient-outcomes-from-older-60-hypertensive-living-donors/. Accessed May 26, 2022.
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