Increasing Obesity and Diabetes Prevalence in the United States End-Stage Renal Disease Population
1Surgery, University of Alabama at Birmingham, Birmingham, AL
2Medicine, University of Pennsylvania, Philadelphia, PA.
Meeting: 2018 American Transplant Congress
Abstract number: B326
Session Information
Session Name: Poster Session B: Non-Organ Specific: Economics, Public Policy, Allocation, Ethics
Session Type: Poster Session
Date: Sunday, June 3, 2018
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall 4EF
Background: Obesity and diabetes have both become national epidemics in the United States, and are associated with increased risk for comorbid diseases including end-stage renal disease (ESRD). Among ESRD patients, obesity may improve dialysis-survival but decreases likelihood of transplantation, and as such, obesity prevalence may directly impact growth of the incident dialysis population.
Methods: Incident adult ESRD patients with complete body mass index (BMI, kg/m2) data were identified from the United States Renal Data System from 01/01/1995-12/31/2010 (n=1,822,598). Data from the Behavioral Risk Factor Surveillance System of the Centers for Disease Control and Prevention (n=4,303,471) represented the US population when weighted. Trends in BMI, obesity classes I (BMI of 30-34.9), II (BMI of 35-39.9), and diabetes prevalence were examined by year of dialysis initiation. Trends in mean BMI slope and diabetes prevalence were compared between the ESRD and US populations using linear regression.
Results: Median BMI of ESRD patients in 1995 was 25.2 as compared to 29.4 in 2010, a 16.7% increase, while the US population's mean BMI increased from 25.3 in 1995 to 27.2 in 2010, a 7.5% increase. Comparable trends were noted with respect to prevalence of obesity classes I and II. Diabetes prevalence increased from 43% in 1995 to 55% in 2012, a 27.9% increase (Table). BMI increase among the ESRD population was significantly more rapid than among the US population (β: 0.15, 95% CI: 0.14-0.17, p<0.001) as was the increase of diabetes prevalence (β: 0.40, 95% CI: 0.29-0.50, p<0.001) (Figures).
Conclusion: The mean BMI of ESRD patients and the prevalence of diabetes among the ESRD population are increasing more rapidly than the US population. Given decreased access to kidney transplantation among obese ESRD patients, future research should be directed at controlling healthcare expenditures by identifying strategies to address the growing obesity epidemic in the United States.
CITATION INFORMATION: Shelton B., McWilliams D., MacLennan P., Reed R., Mustian M., Sawinski D., Locke J. Increasing Obesity and Diabetes Prevalence in the United States End-Stage Renal Disease Population Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Shelton B, McWilliams D, MacLennan P, Reed R, Mustian M, Sawinski D, Locke J. Increasing Obesity and Diabetes Prevalence in the United States End-Stage Renal Disease Population [abstract]. https://atcmeetingabstracts.com/abstract/increasing-obesity-and-diabetes-prevalence-in-the-united-states-end-stage-renal-disease-population/. Accessed May 8, 2025.« Back to 2018 American Transplant Congress