ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Impact of Organ Donor Infections on Kidney Transplant Recipient Outcomes

M. Santarossa1, C. Muran2, S. Sanchez2, L. Heinrich2, J. Yoo3, F. Albarillo1, S. Akkina3, N. Clark1, G. Reid1

1Department of Medicine, Division of Infectious Diseases, Loyola University Medical Center, Maywood, IL, 2Department of Pharmacy, Loyola University Medical Center, Maywood, IL, 3Department of Medicine, Division of Transplant Nephrology, Loyola University Medical Center, Maywood, IL

Meeting: 2020 American Transplant Congress

Abstract number: B-195

Keywords: Cadaveric organs, Infection, Kidney transplantation

Session Information

Session Name: Poster Session B: Kidney Infectious Excluding Polyoma & Viral Hepatitis

Session Type: Poster Session

Date: Saturday, May 30, 2020

Session Time: 3:15pm-4:00pm

 Presentation Time: 3:30pm-4:00pm

Location: Virtual

*Purpose: Donor-derived infections can lead to significant morbidity and mortality in organ transplant recipients. There is variability by center on treatment of positive donor cultures and insufficient data on associated outcomes. In this study, we examined how positive donor cultures are treated in recipients of deceased donor renal transplants and the impact on graft and patient survival.

*Methods: A retrospective chart review of all renal transplant recipients with positive blood, urine, or perfusion fluid donor cultures was performed from January 1, 2017 to December 31, 2018. Patients were excluded if they were <18 years of age, there was insufficient documentation in the medical record, or they had a simultaneous organ transplant (n=9).

*Results: There were 40 renal transplant recipients with positive donor cultures in the cohort. The mean age was 50.6, with 58% male recipients. Twenty-nine patients (73%) received an infectious diseases (ID) consult to recommend antimicrobial therapy. There were 10 donors with positive blood cultures (25%), 17 donors with positive perfusion fluid cultures (42.5%), and 15 donors with positive urine cultures (37.5%). Twenty-six recipients received effective therapy targeting the donor culture (65%). The mean duration of effective treatment for positive donor cultures was 14.8 days and the mean length of stay for all recipients was 6.6 days. Presence of an ID consult was associated with significantly more effective treatment for donor cultures (p=0.001), however effective treatment was not associated with a decrease in clinical outcomes such as graft loss, mortality, Clostridium difficileinfection, or re-admission rates within 6 months of transplant.

*Conclusions: At our institution, most renal transplant patients with positive donor cultures receive effective antimicrobials to target these pathogens and most receive an ID consult. More data is needed to determine the optimal route and duration of therapy. The rate of complications for our patients was low, perhaps due to most patients receiving effective therapy.

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Santarossa M, Muran C, Sanchez S, Heinrich L, Yoo J, Albarillo F, Akkina S, Clark N, Reid G. Impact of Organ Donor Infections on Kidney Transplant Recipient Outcomes [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/impact-of-organ-donor-infections-on-kidney-transplant-recipient-outcomes/. Accessed May 11, 2025.

« Back to 2020 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences