ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

GFR Outcomes for Recipients and Donors with IgA, FSGS, Alports and Thin Basement Membrane Disease: A Comparison of Living Related to Unrelated Donors

D. Keys, S. Jackson, S. Riad, R. Spong, V. Vakil, A. Matas, P. Nachman

University of Minnesota, Minneapolis, MN

Meeting: 2019 American Transplant Congress

Abstract number: B128

Keywords: Donation, Glomerular filtration rate (GFR), Kidney transplantation, Renal function

Session Information

Session Name: Poster Session B: Kidney Donor Selection / Management Issues

Session Type: Poster Session

Date: Sunday, June 2, 2019

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

*Purpose: Prior studies have shown an increase rate of graft loss in patients that receive living donor kidney transplants from relatives in IgA, FSGS, and other potentially genetic kidney diseases. Also, there is data that shows an increase risk of ESRD in donors that donate to a relative (Wainright, AJT, 2018). As such, we sought to compare the eGFR of both donors and recipients, of living related vs unrelated donors in recipients with IgA, FSGS, Alports and TBM disease.

*Methods: 377 living donor transplants with recipients with IgA, FSGS, Alports and TBM disease. Of these, 260 were related and 117 were unrelated. We then looked at eGFR of the donors and recipients post transplant/donation. The eGFR was determined by CKD-Epi Cr.

*Results: The characteristics of the donors are listed in Table 1. The eGFR pattern of living related vs unrelated donors after transplant is shown in Figure 1. There is no significant difference in change in GFR post donation in related vs unrelated donors. In addition, for related vs unrelated donors, there was no significant difference in the development of post donation hypertension or proteinuria (Figure 2). Finally, in recipients with ESRD due to IgA, FSGS, Alports, and TBM disease, there was no difference in post transplant eGFR comparing recipients of related vs unrelated live donors.

*Conclusions: For living donors, donating to recipients with ESRD due to IgA, FSGS, Alports and TBM disease, there was no difference in post donation eGFR between related vs unrelated donors or in the incidence of post donation hypertension or proteinuria. For the recipients, the trajectory of eGFR did not differ in related donors compared with unrelated donors.

 border=

 border=

 border=

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

To cite this abstract in AMA style:

Keys D, Jackson S, Riad S, Spong R, Vakil V, Matas A, Nachman P. GFR Outcomes for Recipients and Donors with IgA, FSGS, Alports and Thin Basement Membrane Disease: A Comparison of Living Related to Unrelated Donors [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/gfr-outcomes-for-recipients-and-donors-with-iga-fsgs-alports-and-thin-basement-membrane-disease-a-comparison-of-living-related-to-unrelated-donors/. Accessed June 2, 2025.

« Back to 2019 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences