*Purpose: Inherited hypoparathyroidism can lead to life threatening episodes of hypocalcaemia as well as to end stage renal failure at a young age. We are reporting about the first case of simultaneous Living donor Parathyroid and Kidney transplantation in a child as a curative approach for that.

*Methods: An 11 year-old girl suffered from hypoparathyroidism and from end stage renal failure as a consequence to an autosomal dominant mutation in the calcium sensing receptor with Bartter type V (exon 7 c.2528C>A). She was on heamodialysis via a right tunnelled line as well as on continuous PTH infusion via a subcutaneous pump. She simultaneously received a kidney and the right upper pole parathyroid gland from her 43 year old father. The cold ischemia times were 5h and 7h, respectively.

*Results: The kidney graft showed primary function with a Creatinine of 55 umol/L on postoperative day 3. Similarly, calcium infusions were stopped on the same day due to hypercalcaemia. Her intrinsic PTH at the time was 3 ng/L and the rate of synthetic PTH infusion via the pump was reduced on day 6 post transplantation. On day 8, after a further decrease of the PTH infusion, she remained normocalcaemic and had an intrinsic PTH level of 21ng/L and 28ng/L on day 8 and 9 respectively.

*Conclusions: Our case demonstrates that obtaining a kidney and a parathyroid gland simultaneously is safe and feasible and has the potential to cure primary hypoparathyroidism and renal failure. For patients already receiving immunosuppression for renal transplantation, there is little additional risk involved. A handful of similar cases were reported previously but none in the paediatric population.

« Back to 2020 American Transplant Congress