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Factors Associated With Rehospitalization and High Cost Among Health Plan Members Receiving Kidney Transplants

E. Lee,1 Y. Zhou,2 B. Suehs,2 B. Franks,1 B. Kassman,1 J. Spalding,1 G. Thal.1

1Astellas Scientific and Medical Affairs, Northbrook, IL
2Comprehensive Health Insights, Humana, Louisville, KY.

Meeting: 2015 American Transplant Congress

Abstract number: A238

Keywords: Kidney transplantation

Session Information

Session Name: Poster Session A: Non Organ Specific, Economics, Public Policy, Allocation, Ethics

Session Type: Poster Session

Date: Saturday, May 2, 2015

Session Time: 5:30pm-7:30pm

 Presentation Time: 5:30pm-7:30pm

Location: Exhibit Hall E

Purpose

Aims were to develop a claims-based algorithm to identify kidney transplant cases and to examine clinical and economic outcomes among health plan members undergoing kidney transplantation.

Methods

This study was a retrospective analysis of administrative claims data from a large managed care organization. Kidney transplant cases were identified using a claims-based algorithm consisting of ICD-9-CM, CPT, and DRG codes associated with medical claims from Jan 1 2007 to Dec 31 2012. Patient and plan characteristics were measured during a 12-month period preceding the index transplant hospitalization. Outcomes including transplant-related length of stay (TR-LOS), rehospitalization (RH), and healthcare costs were measured during a 12-month period after the index hospitalization. Factors associated with RH and high cost (defined as the top tertile of cases by total post-transplant cost) were identified.

Results

A total of 745 kidney transplant cases were identified using the claims-based algorithm. Of these cases, 98.4% (n=733) were validated against internal health plan transplant data. After applying continuous enrollment criteria, 316 members were included in the analysis. Kidney transplant members were primarily male (58.2%, n=184) and mean (SD) age was 58.5 (12.7) years. Mean (SD) length of stay for the transplant hospitalization was 8.6 (5.6) days. Twelve-month all-cause RH was observed for 67.7% (n=214) of members. Mean (SD) number of RHs was 2.3 (4.2) overall. In bivariate analyses, higher Elixhauser score (P=0.004), longer TR-LOS (P=0.004), graft failure (P<0.001), and retransplantation (P<0.001) were associated with RH. The most commonly observed diagnosis associated with RH were complication of transplanted kidney (n = 92, 43.0%), acute renal failure (n=47, 22.0%), and fever (n=41, 19.2%). Median pre-transplant, transplant admission, and post-discharge healthcare costs were $63,595, $58,166, and $46,535, respectively. In bivariate analysis, younger age (P=0.039), higher Elixhauser score (P=0.001), longer TR-LOS (P<0.001), RH (P<0.001), graft failure (P<0.001), and retransplantation (P<0.001) were associated with high costs.

Conclusion

Administrative claims data may be useful for health plans to identify kidney transplantation cases, measure health-related outcomes including RH and healthcare costs, and identify potential drivers of cost.

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To cite this abstract in AMA style:

Lee E, Zhou Y, Suehs B, Franks B, Kassman B, Spalding J, Thal G. Factors Associated With Rehospitalization and High Cost Among Health Plan Members Receiving Kidney Transplants [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/factors-associated-with-rehospitalization-and-high-cost-among-health-plan-members-receiving-kidney-transplants/. Accessed May 17, 2025.

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