Effect of Blood Pressure Just Before Release of the Vascular Clamps on the Renal Function of Kidney Transplantation Recipients: A Retrospective Study.
1Surgery, Tomishiro Central Hospital, Tomishiro-shi, Okinawa, Japan
2Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan
Meeting: 2017 American Transplant Congress
Abstract number: B134
Keywords: Kidney transplantation, Renal function
Session Information
Session Name: Poster Session B: Kidney Complications II
Session Type: Poster Session
Date: Sunday, April 30, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
OBJECTIVE: To assess the effect of blood pressure just before release of the vascular clamps on the renal function of kidney transplantation (KTx) recipients.
METHODS: We retrospectively evaluated 89 patients who underwent KTx at our institution between August 2011 and October 2016. All the participants were given adequate instructions verbally and provided written informed consent. We measured systolic blood pressure (SBP) using the arterial line just before release of the vascular clamps. To evaluate renal function, we measured the serum creatinine level and calculated the estimated glomerular filtration rate (eGFR) at 1 day and 1 year after KTx. The eGFR was calculated as follows: eGFR = 194 [times] Scr−1.094 [times] Age−0.287 (and [times]0.739 for women). Patients were classified into high and low blood pressure groups based on SBP of ≥140 and <140 mm Hg, respectively. We compared renal function between the high (n = 51) and low blood pressure groups (n = 38).
RESULTS: The patients' characteristics before KTx, including sex, age, hypertension, body mass index, SBP, serum creatinine level, and eGFR, did not differ significantly between the 2 groups. The eGFRs of the high blood pressure group in comparison with those of the low blood pressure group at 1 day, 2 days, 3 days, 1 week, 2 weeks, 1 month, 3 months, 6 months, and 1 year after KTx were as follows: 21.0 ± 12.7 vs. 17.0 ± 8.9 mL/(min[times]1.73 m2) (p = 0.049), 42.3 ± 23.9 vs. 33.7 ± 18.0 mL/(min[times]1.73 m2) (p = 0.034), 47.3 ± 22.5 vs. 38.9 ± 19.7 mL/(min[times]1.73 m2) (p = 0.036), 56.6 ± 22.0 vs. 50.0 ± 20.5 mL/(min[times]1.73 m2) (p = 0.076), 60.9 ± 21.6 vs. 56.2 ± 19.0 mL/(min[times]1.73 m2) (p = 0.145), 54.5 ± 18.1 vs. 54.7 ± 17.3 mL/(min[times]1.73 m2) (p = 0.519), 51.8 ± 16.8 vs. 55.5 ± 17.8 mL/(min[times]1.73 m2) (p = 0.828), 52.0 ± 18.2 vs. 53.8 ± 14.5 mL/(min[times]1.73 m2) (p = 0.676), and 53.3 ± 17.1 vs. 52.2 ± 11.7 mL/(min[times]1.73 m2) (p = 0.376), respectively (Figure 1).
CONCLUSIONS: Kidney function, especially eGFR, in the high blood pressure group was better than that in the low blood pressure group within 1 month of KTx.
CITATION INFORMATION: Tsujimura K, Ota M, Ishida H, Tanabe K. Effect of Blood Pressure Just Before Release of the Vascular Clamps on the Renal Function of Kidney Transplantation Recipients: A Retrospective Study. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Tsujimura K, Ota M, Ishida H, Tanabe K. Effect of Blood Pressure Just Before Release of the Vascular Clamps on the Renal Function of Kidney Transplantation Recipients: A Retrospective Study. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/effect-of-blood-pressure-just-before-release-of-the-vascular-clamps-on-the-renal-function-of-kidney-transplantation-recipients-a-retrospective-study/. Accessed November 21, 2024.« Back to 2017 American Transplant Congress