ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Dual Kidney Transplantation Reduces Organ Wastage and Increases the Number of Kidney Transplants Available to Elderly Candidates

W. Bry, V. Peddi, H. Mahanty, A. Hassoun, S. Katznelson, P. Patel, L. Bohannon, L. Lu, N. Neidlinger, K. Ueda, R. Osorio

Department of Transplantation, California Pacific Medical Center, San Francisco, CA

Meeting: 2013 American Transplant Congress

Abstract number: D1544

Changes in national kidney allocation are anticipated to begin in 2014. The proposed system redefines ECD kidneys, resulting in a reduction in both the quantity and quality of ECD kidneys being offered. This is predicted to reduce the number of kidney transplants in elderly candidates. Currently, as many as 40% of ECD kidneys are discarded. Many of these could be utilized as dual kidney transplants. Reducing the number of discarded kidneys through dual transplantation could address the anticipated dropoff in ECD transplants. We report on our experience with 19 dual kidney transplants over the past four years.

Since March of 2008, we have performed 19 dual kidney transplants. All kidneys were turned down by local programs for transplantation singly. All kidneys were cold stored with UW solution. 16 of 19 transplants had immediate function.

Donor Characteristics
  Donor Age Donor KDPI* Donor Hypertension Donor Diabetes Stroke Admittting Creatinine % Glomerulo sclerosis
Mean 64.7 .89       1.0 16%
Range 51-73 .64-1.0 13 of 19 3 of 19 15 of 19 .44-1.53 0%-42%
* KDPI- Kidney Donor Profile Index

Recipients were treated with Thymoglobulin induction (3 mg/kg unsensitized; 6 mg/kg sensitized) followed by triple drug immunosuppression with Prograf, Cellcept and Prednisone. Average length of stay was 6 days.

Recipient Characteristics and Outcomes
  Recipient Age PRA>70% Followup Patient Survival Graft Survival Surgical Complications* Current Creatinine
Mean 64 6 of 19 21 months 94% 89% 4 of 19 1.08
Range 34-81   2-56 months       0.66-1.83
* 1 ureteral; 2 infectious; 1 vascular: 3 of 4 resolved

Patient and graft survival and graft function compare favorably to ECD kidneys transplanted singly, despite utilizing donors with higher KDPI's. One patient lost his transplant from gross noncompliance; this was the only case in which rejection was diagnosed. Another transplant failed from deep space wound infection; the patient died on dialysis two years later from heart disease and lymphoma.

Dual kidney transplantation is a viable option to reduce the impact of allocation changes that are predicted to reduce access to transplantation for elderly candidates.

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Bry W, Peddi V, Mahanty H, Hassoun A, Katznelson S, Patel P, Bohannon L, Lu L, Neidlinger N, Ueda K, Osorio R. Dual Kidney Transplantation Reduces Organ Wastage and Increases the Number of Kidney Transplants Available to Elderly Candidates [abstract]. Am J Transplant. 2013; 13 (suppl 5). https://atcmeetingabstracts.com/abstract/dual-kidney-transplantation-reduces-organ-wastage-and-increases-the-number-of-kidney-transplants-available-to-elderly-candidates/. Accessed May 14, 2025.

« Back to 2013 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences