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Current Practice and Center-Level Variation in Simultaneous Liver-Kidney Listing.

X. Luo, A. Massie, J. Garonzik-Wang, R. Choudhury, A. Shaffer, S. Zhou, D. Segev.

Johns Hopkins, Baltimore, MD

Meeting: 2017 American Transplant Congress

Abstract number: 425

Keywords: Kidney/liver transplantation, Waiting lists

Session Information

Session Name: Concurrent Session: Kidney Issues in Liver Transplantation

Session Type: Concurrent Session

Date: Tuesday, May 2, 2017

Session Time: 2:30pm-4:00pm

 Presentation Time: 2:30pm-2:42pm

Location: E451b

The OPTN has proposed medical eligibility criteria to determine which transplant candidates are appropriate for SLK vs liver-alone transplantation. We investigated center variation of SLK listing, in light of the criteria.

Methods: We used SRTR data to study 14,419 liver transplant candidates after Share-35, who met the SLK criteria. We calculated the proportion of candidates at each center who listed for SLK within 6 months of eligibility. Multi-level Poisson regression was used to estimate the center-specific probability of SLK listing, adjusting for characteristics.

Results: Among eligible patients, 25.6% were listed for SLK within 6-months. However, the proportion of SLK listing ranged from 0%-100% across centers (Figure 1). African American race (2.24x), male gender (1.37x), higher MELD (among MELD<25) (1.61x), prior transplant history (1.61x), diabetes (1.52x), and hypertension (1.71x) were associated with a greater chance of SLK listing. Conversely, older age (0.74x), higher MELD (among MELD≥25) (0.82x), and exception-status (0.56x) were associated with a less chance of SLK listing (Table). Even after adjustment, the probability ranged from 2.5%-99.9% across centers (Figure 2).

Conclusions: Due to the center variation in listing, SLK eligible candidates may be severely disadvantaged in access to SLK based on center listing practices.

Relative chance of SLK listing
Age per 10 yr 0.710.740.76
Male 1.281.371.47
African-American 2.042.242.46
MELD per 5 points (MELD<25) 1.511.611.72
MELD per 5 points (MELD≥25) 0.79 0.82 0.86
Exception status 0.49 0.56 0.64
eGFR per 5 0.510.520.53
Prior transplant 1.451.611.78
Diabetes 1.421.521.63
Hypertension 1.591.711.83

CITATION INFORMATION: Luo X, Massie A, Garonzik-Wang J, Choudhury R, Shaffer A, Zhou S, Segev D. Current Practice and Center-Level Variation in Simultaneous Liver-Kidney Listing. Am J Transplant. 2017;17 (suppl 3).

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To cite this abstract in AMA style:

Luo X, Massie A, Garonzik-Wang J, Choudhury R, Shaffer A, Zhou S, Segev D. Current Practice and Center-Level Variation in Simultaneous Liver-Kidney Listing. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/current-practice-and-center-level-variation-in-simultaneous-liver-kidney-listing/. Accessed May 9, 2025.

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