COVID-19+ Kidney Transplant in US Veterans: An Opportunity to Increase Transplant Rates
Surgery, Columbia Vagelos College of Medicine and Surgery, New York, NY
Meeting: 2022 American Transplant Congress
Abstract number: 755
Keywords: Cadaveric organs, COVID-19, Infection, Kidney transplantation
Topic: Clinical Science » Kidney » 32 - Kidney Deceased Donor Selection
Session Information
Session Name: Kidney Deceased Donor Selection
Session Type: Poster Abstract
Date: Saturday, June 4, 2022
Session Time: 5:30pm-7:00pm
Presentation Time: 5:30pm-7:00pm
Location: Hynes Halls C & D
*Purpose: US veterans are less likely to be transplanted. This disparity is related to donor shortage. This study seeks to increase access to transplant of US veterans to transplants using covid+ organs. This provides high quality organs to underserved population, reduce discards and is safe. Report of safety of this strategy. Early reports demonstrates safety in using these organs.
*Methods: Case presentation of two veterans transplanted with covid+ organs. Recipient and donor characteristics highlighted including vaccine status, antibody level (IgG) against Sars-CoV-2 prior to and following transplant. Organ function is reported and complications. Induction agent using non-depleting agent recorded. Informed consent obtained for covid+ organ. Infectious disease consultation. IgG antibody level check prior to transplant, and post transplant.
*Results: Two cases reported. Both had no complications related to covid. Excellent donors with KDPI <30. Cycle threshold 16 and above. Sequence 193 and 225. EPTS >85. Simulect and steroids used in both cases. Cold time short >16 hours. Both brain dead donors. LOS 7 and 8 days. PRA 0%. Donor blood group A and O. DGF in one recipient which recovered after 2 weeks see figure. The recipients had initially high antibody level which declined post transplant by 50%. See fig.
*Conclusions: Using Sars-CoV-2 donors is safe and provides a source of potential high quality organs in US Veterans who are generally underserved using informed consent. Full vaccination in recipient is a prerequisite.
Donor | Age | KDPI | Wt | Cycle thresh | Seq# | Blood grp. | CIT |
A | 26 | 23 | 68 | 20/40 | 193 | A | 11h 16 |
B | 18 | 34 | 123 | 16/40 | 225 | O | 15h 52 |
Recipient | Age | EPTS | Induct. | Vaccine status | LOS | PRA | Complications |
A | 65 | 92 | Sim/
steroid
|
2
Cov. PNA
|
7 | 0 | None |
B | 59 | 85 | Sim/
steroid
|
3 series | 8 | 0 | DGF |
To cite this abstract in AMA style:
Whittaker VE. COVID-19+ Kidney Transplant in US Veterans: An Opportunity to Increase Transplant Rates [abstract]. Am J Transplant. 2022; 22 (suppl 3). https://atcmeetingabstracts.com/abstract/covid-19-kidney-transplant-in-us-veterans-an-opportunity-to-increase-transplant-rates/. Accessed November 21, 2024.« Back to 2022 American Transplant Congress