Angioplasty versus Stent in the Treatment of Transplant Renal Artery Stenosis.
1Transplant Nephrology, UC Davis Medical Center, Sacramento, CA
2Radiology, UC Davis Medical Center, Sacramento, CA
3Biostatistics, UC Davis School of Medicine, Davis, CA
Meeting: 2017 American Transplant Congress
Abstract number: B138
Keywords: Angiography, Hypertension, Kidney transplantation, Vascular disease
Session Information
Session Name: Poster Session B: Kidney Complications II
Session Type: Poster Session
Date: Sunday, April 30, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Objective: To compare restenosis rates and treatment efficacy between percutaneous transluminal angioplasty and stent placement in the treatment of transplant renal artery stenosis.
Methods: We conducted a retrospective single-center cohort study of patients who underwent angiography for transplant renal artery stenosis between 1/1/2006 and 9/20/2016. We compared the rates of restenosis in those patients who received angioplasty alone versus those who received a stent. Secondary outcomes included serum creatinine and blood pressure after intervention.
Results: 80 patients received angiography and were found to have stenosis of the transplanted renal artery. 57 patients received angioplasty and 23 received stenting. Of the 40 patients who had follow-up restenosis determination, 15 of 28 (54%) developed restenosis in the angioplasty group while 2 of 12 (17%) developed restenosis in the stented group (p=0.03) when restenosis was determined by ultrasound or repeat angiography. Repeat angiography occurred in 8 patients (29%) who were angioplastied and 3 patients (25%) who were stented (p=0.8). The stented group had significantly lower residual stenosis post-intervention (27.9% compared to 2.5%, p<0.001). Serum creatinine and blood pressures were not significantly different between the two groups at 30, 90 or 360 days post intervention, though there was a trend toward lower serum creatinine and blood pressures in the stented group (Figure).
Conclusion: Stenting of transplant renal artery stenosis results in less residual stenosis compared with angioplasty alone and may lead to lower rates of restenosis. Clinical implications of restenosis need further definition, but since optimal treatment of transplant renal artery stenosis is unknown, our study supports the need for further clinical studies.
CITATION INFORMATION: Chen L.-X, Fananapazir G, Bang H, Gandhi M, Alnimri M, Gallay B, De Mattos A. Angioplasty versus Stent in the Treatment of Transplant Renal Artery Stenosis. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Chen L-X, Fananapazir G, Bang H, Gandhi M, Alnimri M, Gallay B, Mattos ADe. Angioplasty versus Stent in the Treatment of Transplant Renal Artery Stenosis. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/angioplasty-versus-stent-in-the-treatment-of-transplant-renal-artery-stenosis/. Accessed May 11, 2025.« Back to 2017 American Transplant Congress