*Purpose: The Kidney Team at Home program is an educational intervention aimed at patients with chronic kidney disease to assist them in their choice for kidney replacement therapy. Previous studies have shown that the intervention results in an increase in knowledge and communication on kidney replacement therapy, and eventually in an increase in the number of living donor kidney transplantations. The present study assesses the cost-effectiveness of the intervention compared to standard care.

*Methods: A dynamic probabilistic Markov model was used to estimate the monetary and health benefits of the intervention in the Netherlands over 10 years. Data on costs and health-related quality of life were derived from the literature. Transition probabilities, prevalence and incidence rates were calculated using a large national database. An optimistic and a pessimistic implementation scenario were compared to a base case scenario with only standard care.

*Results: In both the optimistic and pessimistic scenario, the intervention is cost-effective and dominant compared to standard-care: savings were €108,681,985 and €51,770,060 and the benefits were 1382 and 695 QALYs respectively.

*Conclusions: The Kidney Team at Home intervention has been shown to be cost-effective compared to the standard care. This is caused by the superior health effects and the reduction of costs associated with transplantation, and the relatively small incremental costs of the intervention. Successful nationwide implementation of the intervention could lead to an increase in the demand for transplantation and to a reduced need for dialysis facilities in the Netherlands.

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