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Increased Costs, Cold Ischemia Time, and Sharing Associated with Removing DSA and OPTN Region from Kidney Allocation: A Single-Center Analysis

R. Forbes1, A. Dreher1, E. Zavala2, L. A. Hickman1, L. Smith3, J. Lawson1, D. Shaffer1, B. P. Concepcion1

1Vanderbilt University Medical Center, Nashville, TN, 2Transplant Center, Vanderbilt University Medical Center, Nashville, TN, 3Vanderbilt Transplant Center, Nashville, TN

Meeting: 2022 American Transplant Congress

Abstract number: 1336

Keywords: Allocation, Economics, Kidney transplantation, Outcome

Topic: Clinical Science » Public Policy » 21 - Non-Organ Specific: Public Policy & Allocation

Session Information

Session Name: Non-Organ Specific: Public Policy & Allocation

Session Type: Poster Abstract

Date: Monday, June 6, 2022

Session Time: 7:00pm-8:00pm

 Presentation Time: 7:00pm-8:00pm

Location: Hynes Halls C & D

*Purpose: On March 15, 2021, Donation Service Area (DSA) and OPTN Region were removed from kidney allocation and replaced with a 250 nautical mile (NM) fixed circle around the donor hospital with proximity points in an effort to remove geography as a barrier to transplantation. Although monitoring reports show increased transplants, decreased discards, and broader sharing, we wanted to determine if there were associated costs or outcomes at the transplant center level.

*Methods: This retrospective, single center study includes all adult, deceased donor kidney transplants that occurred 6 months prior to and 6 months after March 15, 2021 at our center. Clinical and cost variables were collected and cohorts were compared as pre-policy change (9/15/2020-3/14/2021) and post-policy change (3/15/2021-09/14/2021) using Wilcoxon Rank Sum or chi-squared tests for categorical variables.

*Results: A total of 222 patients were included in our analyses (105 pre- and 117 post-). There was no difference in age, gender, race, blood type, dialysis vintage, cPRA, KDPI, HLA-mismatch, or length of hospital stay. There was a significant increase in broader sharing on both a regional and national level with reduction in local organs transplanted (p<0.001). There were increased cold ischemia times (15.5 vs. 17.4 hours, p<0.03). A 5.2% increase in costs post-policy change for direct patient care also occurred (p<0.05).

*Conclusions: The intended goals of broader sharing with the elimination of DSA and OPTN Region are being realized. With more regional and national sharing concerns have been raised about increases in cold ischemia times which may affect outcomes and increasing costs for the overall system as organs travel further distances. We present center-level data that costs have been higher post-policy change. It will be important to continue to monitor and present granular data with continuous distribution for kidney allocation.

Pre- and Post-250NM policy change: Factors Impacted
Pre Post p-value
CIT (h) 15.5 17.4 0.02
% COST INCREASE – 5.2 0.04
SHARING <0.001
Local 88 37
Regional 4 20
National 13 60
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To cite this abstract in AMA style:

Forbes R, Dreher A, Zavala E, Hickman LA, Smith L, Lawson J, Shaffer D, Concepcion BP. Increased Costs, Cold Ischemia Time, and Sharing Associated with Removing DSA and OPTN Region from Kidney Allocation: A Single-Center Analysis [abstract]. Am J Transplant. 2022; 22 (suppl 3). https://atcmeetingabstracts.com/abstract/increased-costs-cold-ischemia-time-and-sharing-associated-with-removing-dsa-and-optn-region-from-kidney-allocation-a-single-center-analysis/. Accessed May 18, 2025.

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