*Purpose: To compare outcomes of the initial series of patients who underwent single port (SP) robotic kidney transplantation (KTP) with the standard open KTP.

*Methods: Using our institutional review board (IRB) approved databases, we compared a prospective cohort of 12 consecutive patients who underwent SP robotic KTP from Oct 2019 to Oct 2021 with a retrospective cohort of 12 matched patients who had open KTP. Patients were matched for donor type, the kidney donor profile index (KDPI) in deceased donors, recipient age, and history of diabetes. The comparison of normal data and percentages was performed using the T-test and the “N-1” Chi-squared test respectively.

*Results: Baseline and perioperative data of both groups are presented in the table 1. No patients in SP arm were converted to open surgery. There were no intra- or postoperative complications ≥ Clavien grade 2 in either group. The mean (SD) inpatient morphine milligram equivalents (MME) score was 44.91 (40.15) and 149.16 (119.70) in SP and open groups respectively (P = 0.0091). 6-, and 12-month graft and patient survival were 100% in both arms. There was no significant difference in mean creatinine level at 1, 6, and 12 months between groups.

*Conclusions: Single port robotic kidney transplantation is associated with similar safety and allograft function compared to open kidney transplantation with the added benefit of less postoperative narcotics requirement. Larger series are required in this setting.

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