*Purpose: The Stanford Integrated Psycosocial Assessment for Transplant (SIPAT) score predicts outcome after heart transplantation (HTx). Compliance with medications and clinic visits are important leading up to transplant to ensure good outcomes. We have been using the SIPAT score to assess our patients for HTx. We now report our single center experience to determine the value of this assessment.

*Methods: Between 2003 and 2020, we assessed 214 HTx candidates undergoing evaluation. All patients received a SIPAT score. Correlation between SIPAT scores and 1-year survival, 1-year freedom from any treated rejection (ATR), cardiac allograft vasculopathy (CAV: stenosis ≥30%), and non-fatal major adverse cardiac events (NF-MACE: myocardial infarction, new congestive heart failure, percutaneous coronary intervention, implantable cardioverter defibrillator/pacemaker implant, stroke) were assessed using receiver operator characteristic (ROC) curves.

*Results: The area under the ROC curves for 1-year survival and 1-year freedom from ATR and NF-MACE were less than 0.5, suggesting that SIPAT score would perform worse as a classifier for these outcomes than a random classifier. The area under the curve for 1-year freedom from CAV was 0.617, suggesting that SIPAT score is a poor classifier in predicting CAV in patients.

*Conclusions: A high pre-HTx SIPAT score by itself does not appear to be a sole indicator of poor post-transplant outcome. It should be used in combination with other societal and medical factors to determine heart transplant candidacy.

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