*Purpose: Uterus transplantation (UTx) is a novel treatment modality for women with absolute uterine factor infertility. The majority of uterine transplants performed in the world are from living donation. We report here our experience with 7 uterine transplants performed with cadaveric donors.

*Methods: Key recipient inclusion criteria for this IRB approved study were: a diagnosis of uterine factor infertility, a BMI < 30 kg/m², ages 18 to 45 and embryos produced between the ages 21 to 39. Key donor criteria were: a healthy uterus and acceptable serologies. Donor hospital located within a radius of 250 miles of our transplant center and a history of previous term pregnancies were prioritized.

*Results: A total of 7 UTx from brain dead donors have been performed since 2016. Indication was Mayer-Rokitansky-Küster-Hauser syndrome in all cases. The median operative time was 7 hrs 46 min (6:49-8:52) and median cold ischemia time was 5 hrs 29 min (4:14-5:48). The median hospital stay was 7(6-14) days. One of the transplants resulted in the delivery of a healthy baby, a second patient is pregnant (second trimester) and one is scheduled for embryo transfer. Two recipients are 4 months after transplant with a viable graft. Two of these six patients experienced bouts of severe rejection successfully treated without graft loss. Interestingly, one rejected graft hosted the full term pregnancy. All patients are alive, 2 grafts were lost (Table 1- complications).

*Conclusions: Our results suggest that deceased donor uterus transplantation is an effective strategy for the treatment of uterine factor infertility avoiding the potential morbidity and mortality related to living donor surgeries.

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