*Purpose: As the National kidney shortage continues to rise, efforts to expand the donor pool by utilizing living kidneys from stone-forming donors have become widely accepted in the United States. We analyzed the living donor database to compare kidney donor outcomes with nephrolithiasis to matched controls without nephrolithiasis.

*Methods: At our center, kidney donor candidates with history of two stones or less in the past five years are allowed to donate. We identified kidney donors with a history of nephrolithiasis and matched them 1:5 with controls. We matched for pre-donation age, BMI, eGFR (using CKD EPI equation), sex, donation year, history of hypertension, systolic and diastolic blood pressures, blood glucose, relation to the recipient, smoking history, and education status. Kaplan-Meier curves were generated to compare the incidence of post-donation hypertension, cardiovascular events, diabetes and mortality.

*Results: Two-hundred and ninety-three donors were analyzed. Fifty-five donors were identified with a history of nephrolithiasis before donation and were compared to two hundred and thirty-eight donors without nephrolithiasis. Incidence of hypertension, diabetes, cardiovascular events and mortality did not vary between donors according to their stone-forming history (Figure 1). There were no ESRD cases in either donor group. Post donation length of stay was not different between stone former and non-stone former donors.

*Conclusions: Our data suggest no increased risk of post-donation hypertension, diabetes, cardiovascular events or mortality in stone former as compared to non-stone former donors. Further multi-center analyses may be needed to validate our observations.

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