*Purpose: Not many studies have reported the donor exclusion rates and reason for their decline in US. We aim to report the breakdown of donor exclusion rates and notable increase of non biological donors in the recent years at our Center

*Methods: Total of 382 liver donors were evaluated at our center between Jan 2014 to October 2018. Everyone underwent extensive multidisciplinary evaluation process. Selection criteria for the eligible donors were consistent, compliant and met with our center’s protocol, requirements and criteria for liver biopsy, BMI, GWRW and other medical, surgical, psycho social criteria

*Results: Out of 382 donors, 208 (54.4%) of them were approved and underwent hepatectomies. 138 (36.1%) were declined. 36( 9.2%) were either approved for evaluation or donation or committee or insurance approval, at the time of this study. Out of the 138 donors who were declined, 72 of the donors (52.1%) were excluded due to donor related reasons including medical, and non medical. The non medical reasons included donor choice and fiscal approval. 50 (36.2%) of them were denied due to medical, surgical, behavioral and psycho social causes. 66 (47.8%) of the donors were excluded due to recipient related issues including recipient receiving cadaveric transplant, recipient choice, deterioration of their condition. We also noted a trend toward more non biological donors undergoing evaluation with 176 (46.07%) being biological and 167 (43.7%) non biological, likely due to efforts focused on education and awareness at our Center

*Conclusions: The final exclusion at our center for the liver donors were 36.1%. Out of the excluded donors, 52.1% and 47.8% of them were due to donor and recipient related issues respectively. We report that, there is a trend toward more non biological donors in the recent years due to the efforts focused on the education

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